Search Results - "Andricopulo, A.D."
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Effects of organic solvents on the enzyme activity of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase in calorimetric assays
Published in Analytical biochemistry (01-11-2007)“…In drug discovery programs, dimethyl sulfoxide (DMSO) is a standard solvent widely used in biochemical assays. Despite the extensive use and study of enzymes…”
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2
Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents
Published in Bioorganic & medicinal chemistry letters (15-04-2006)“…Uncompetitive inhibition of Plasmodium falciparum thioredoxin reductase by nitrophenyl derivatives. Plasmodium falciparum thioredoxin reductase (PfTrxR: NADPH…”
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The role of molecular interaction fields on enantioselective and nonselective separation of chiral sulfoxides
Published in Journal of Chromatography A (14-07-2006)“…The separation of a series of 23 asymmetric sulfoxides, including the three proton pump inhibitors (PPI) omeprazole, lansoprazole and pantoprazole was…”
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4
Calorimetry and structure–activity relationships for a series of antimicrobial hydrazides
Published in Thermochimica acta (30-07-2004)“…This paper presents some recent developments on the use of quantitative structure–activity relationships (QSAR) based on biological calorimetry. The…”
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Structure–activity relationships for the analgesic activity of gallic acid derivatives
Published in Farmaco (Società chimica italiana : 1989) (01-11-2000)“…Values of ID 50 for a collection of structurally-related gallic acid derivatives have been employed to create a predictive quantitative structure–activity…”
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