Search Results - "Andriacchi, Thomas"

Muscle and joint function in human locomotion by Pandy, Marcus G, Andriacchi, Thomas P

“…This review describes how computational modeling can be combined with noninvasive gait measurements to describe and explain muscle and joint function in human…”
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The Nature of In Vivo Mechanical Signals That Influence Cartilage Health and Progression to Knee Osteoarthritis by Andriacchi, Thomas P., Favre, Julien

“…Knee osteoarthritis is a disease that can be initiated along multiple pathways that ultimately leads to pain, loss of function and breakdown of the articular…”
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The role of ambulatory mechanics in the initiation and progression of knee osteoarthritis by Andriacchi, Thomas P, Mündermann, Annegret

“…PURPOSE OF REVIEWThis review examines recent in-vivo studies of ambulation and discusses the fundamental role of mechanics of ambulation in the initiation and…”
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Gait Mechanics Influence Healthy Cartilage Morphology and Osteoarthritis of the Knee by Andriacchi, Thomas P, Koo, Seungbum, Scanlan, Sean F

“…The response of healthy and diseased cartilage of the knee to the mechanics of walking is examined, with the goal of providing insight into the relationship…”
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Valgus alignment and lateral compartment knee osteoarthritis: a biomechanical paradox or new insight into knee osteoarthritis? by Andriacchi, Thomas P

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Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4 by Sohn, Dong Hyun, Sokolove, Jeremy, Sharpe, Orr, Erhart, Jennifer C, Chandra, Piyanka E, Lahey, Lauren J, Lindstrom, Tamsin M, Hwang, Inyong, Boyer, Katherine A, Andriacchi, Thomas P, Robinson, William H

“…Osteoarthritis (OA) is a degenerative disease characterized by cartilage breakdown in the synovial joints. The presence of low-grade inflammation in OA joints…”
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The Nature of Age-Related Differences in Knee Function during Walking: Implication for the Development of Knee Osteoarthritis by Boyer, Katherine A, Andriacchi, Thomas P

“…Changes in knee kinematics have been identified in the early stages of osteoarthritis (OA). However, there is a paucity of information on the nature of…”
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New insight in the relationship between regional patterns of knee cartilage thickness, osteoarthritis disease severity, and gait mechanics by Erhart-Hledik, Jennifer C, Favre, Julien, Andriacchi, Thomas P

“…Abstract To test if the relationship between knee kinetics during walking and regional patterns of cartilage thickness is influenced by disease severity we…”
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Dance between biology, mechanics, and structure: A systems-based approach to developing osteoarthritis prevention strategies by Chu, Constance R., Andriacchi, Thomas P.

“…ABSTRACT Osteoarthritis (OA) is a leading cause of human suffering and disability for which disease‐modifying treatments are lacking. OA occurs through complex…”
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Valgus Plus Internal Rotation Moments Increase Anterior Cruciate Ligament Strain More Than Either Alone by SHIN, Choongsoo S, CHAUDHARI, Ajit M, ANDRIACCHI, Thomas P

“…To test the influence of combined knee valgus and internal tibial rotation moment on anterior cruciate ligament (ACL) strain during single-leg landing. We…”
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General scheme to reduce the knee adduction moment by modifying a combination of gait variables by Favre, Julien, Erhart-Hledik, Jennifer C., Chehab, Eric F., Andriacchi, Thomas P.

“…ABSTRACT Reducing the knee adduction moment (KAM) is a promising treatment for medial compartment knee osteoarthritis (OA). Although several gait modifications…”
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The role of inflammation in the initiation of osteoarthritis after meniscal damage by Edd, Shannon N, Giori, Nicholas J, Andriacchi, Thomas P

“…Abstract Meniscal damage and meniscectomy lead to subsequent osteoarthritis (OA) of the knee joint through multiple and diverse mechanisms, yet the interaction…”
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Three-dimensional knee moments of ACL reconstructed and control subjects during gait, stair ascent, and stair descent by Zabala, Michael E, Favre, Julien, Scanlan, Sean F, Donahue, Joseph, Andriacchi, Thomas P

“…Abstract Changes in knee mechanics following anterior cruciate ligament reconstruction (ACLR) have been implicated as a contributor to the development of…”
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A Systems View of Risk Factors for Knee Osteoarthritis Reveals Insights into the Pathogenesis of the Disease by Andriacchi, Thomas P., Favre, Julien, Erhart-Hledik, J. C., Chu, Constance R.

“…Early detection of osteoarthritis (OA) remains a critical yet unsolved multifaceted problem. To address the multifaceted nature of OA a systems model was…”
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The evolution of methods for the capture of human movement leading to markerless motion capture for biomechanical applications by Mündermann, Lars, Corazza, Stefano, Andriacchi, Thomas P

“…Over the centuries the evolution of methods for the capture of human movement has been motivated by the need for new information on the characteristics of…”
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Modification of Knee Flexion Angle Has Patient-Specific Effects on Anterior Cruciate Ligament Injury Risk Factors During Jump Landing by Favre, Julien, Clancy, Caitlin, Dowling, Ariel V., Andriacchi, Thomas P.

“…Background: The incidence of anterior cruciate ligament (ACL) injuries may be decreased through the use of intervention programs that focus on increasing the…”
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The relationship between peak knee extension at heel-strike of walking and the location of thickest femoral cartilage in ACL reconstructed and healthy contralateral knees by Scanlan, Sean F, Favre, Julien, Andriacchi, Thomas P

“…Abstract Reports that knee cartilage health is sensitive to kinematic changes, combined with reports of extension loss following ACL reconstruction,…”
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The knee joint center of rotation is predominantly on the lateral side during normal walking by Koo, Seungbum, Andriacchi, Thomas P

“…Abstract The purpose of this study was to test the hypothesis of whether the center of rotation (COR) in the transverse plane of the knee is in the medial side…”
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The effect of isolated valgus moments on ACL strain during single-leg landing: A simulation study by Shin, Choongsoo S, Chaudhari, Ajit M, Andriacchi, Thomas P

“…Abstract Valgus moments on the knee joint during single-leg landing have been suggested as a risk factor for anterior cruciate ligament (ACL) injury. The…”
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Interactions between kinematics and loading during walking for the normal and ACL deficient knee by Andriacchi, Thomas P., Dyrby, Chris O.

“…The relationships between extrinsic forces acting at the knee and knee kinematics were examined with the purpose of identifying specific phases of the walking…”
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