Search Results - "Andreyeva, Tatyana"
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Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function
Published in PloS one (01-01-2023)“…C-C motif chemokine receptor-like 2 (CCRL2) is a non-signaling 7 transmembrane receptor that binds chemotactic ligands to shape leukocyte recruitment to sites…”
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Journal Article -
2
A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6 + T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation
Published in The Journal of pharmacology and experimental therapeutics (01-07-2023)“…Blocking chemokine receptor C-C chemoattractant cytokine (chemokine) receptor (CCR) 6-dependent T cell migration has therapeutic promise in inflammatory…”
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Journal Article -
3
IL-21 receptor is critical for the development of memory B cell responses
Published in The Journal of immunology (1950) (15-01-2011)“…Development of long-term humoral immunity, characterized by the formation of long-lived plasma cells (PCs) in the bone marrow and memory B cells, is a critical…”
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Journal Article -
4
Rab11 GTPase-Regulated Membrane Trafficking Is Crucial for Tip-Focused Pollen Tube Growth in Tobacco
Published in The Plant cell (01-09-2005)“…Pollen tube growth is a polarized growth process whereby the tip-growing tubes elongate within the female reproductive tissues to deliver sperm cells to the…”
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Journal Article -
5
MyD88 Is Required for the Formation of Long-Term Humoral Immunity to Virus Infection
Published in Journal of Immunology (15-04-2007)“…Development of long-term humoral immunity is a major goal of vaccination, but the mechanisms involved in the formation of long-term Ab responses are still…”
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Journal Article -
6
In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus
Published in mAbs (01-05-2010)“…Using phage display, we generated a panel of optimized neutralizing antibodies against the human and mouse receptors for interleukin 21 (IL-21), a cytokine…”
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Journal Article -
7
Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2
Published in PloS one (20-01-2023)“…C-C motif chemokine receptor-like 2 (CCRL2) is a non-signaling 7 transmembrane receptor that binds chemotactic ligands to shape leukocyte recruitment to sites…”
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Journal Article -
8
The Interleukin‐1 Receptor–Associated Kinase 4 Inhibitor PF‐06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2021)“…Objective To investigate the role of PF‐06650833, a highly potent and selective small‐molecule inhibitor of interleukin‐1–associated kinase 4 (IRAK4), in…”
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Journal Article -
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Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis
Published in The Journal of immunology (1950) (01-11-2013)“…Autoantibody production and immune complex deposition within the kidney promote renal disease in patients with lupus nephritis. Thus, therapeutics that inhibit…”
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Journal Article -
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Quantitative Analysis of Target Coverage and Germinal Center Response by a CXCL13 Neutralizing Antibody in a T-Dependent Mouse Immunization Model
Published in Pharmaceutical research (01-03-2014)“…ABSTRACT Purpose Study the impact of CXCL13 neutralization on germinal center (GC) response in vivo , and build quantitative relationship between target…”
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Journal Article -
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IL-21R is critical for the development of memory responses (150.9)
Published in The Journal of immunology (1950) (01-04-2011)“…Abstract The development of long-term humoral immunity, characterized by the formation of high affinity memory B cells and long-lived plasma cells in the bone…”
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Journal Article -
12
IL-21R is required for the systemic accumulation of activated B and T lymphocytes in MRL lpr mice (117.9)
Published in The Journal of immunology (1950) (01-04-2011)“…Abstract IL-21 is a pleiotropic cytokine that can influence the activation, differentiation and expansion of B and T cells. Lupus prone MRL/MpJ-Faslpr/lpr/J…”
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Journal Article -
13
Regulation of pollen tube growth by Rac-like GTPases
Published in Journal of experimental botany (01-01-2003)“…Plant Rac-like GTPases have been classified phylogenetically into two major groups—class I and class II. Several pollen-expressed class I Rac-like GTPases have…”
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Journal Article Conference Proceeding -
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Role of IL‐21R in the pathogenesis of murine models of SLE
Published in The FASEB journal (01-03-2008)“…Abstract only IL‐21 is a pleiotropic type I cytokine that is secreted by activated CD4 T cells. IL21 has been found to induce apoptosis in resting B cells but…”
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Journal Article -
15
Rab11 GTPase-Regulated Membrane Trafficking Is Crucial for Tip-Focused Pollen Tube Growth in TobaccoW
Published in The Plant cell (01-09-2005)“…Pollen tube growth is a polarized growth process whereby the tip-growing tubes elongate within the female reproductive tissues to deliver sperm cells to the…”
Get full text
Journal Article -
16
110 Role of IL21R in the pathogenesis of murine models of SLE
Published in Cytokine (Philadelphia, Pa.) (01-09-2008)Get full text
Journal Article -
17
Regulation of pollen tube growth by Rac‐like GTPases
Published in Journal of experimental botany (01-01-2003)“…Plant Rac‐like GTPases have been classified phylogenetically into two major groups—class I and class II. Several pollen‐expressed class I Rac‐like GTPases have…”
Get full text
Journal Article