Search Results - "Andrews, W. W."

BCL-2 family proteins: changing partners in the dance towards death by Kale, Justin, Osterlund, Elizabeth J, Andrews, David W

“…The BCL-2 family of proteins controls cell death primarily by direct binding interactions that regulate mitochondrial outer membrane permeabilization (MOMP)…”
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Treatment for Mild Chronic Hypertension during Pregnancy by Tita, Alan T., Szychowski, Jeff M., Boggess, Kim, Dugoff, Lorraine, Sibai, Baha, Lawrence, Kirsten, Hughes, Brenna L., Bell, Joseph, Aagaard, Kjersti, Edwards, Rodney K., Gibson, Kelly, Haas, David M., Plante, Lauren, Metz, Torri, Casey, Brian, Esplin, Sean, Longo, Sherri, Hoffman, Matthew, Saade, George R., Hoppe, Kara K., Foroutan, Janelle, Tuuli, Methodius, Owens, Michelle Y., Simhan, Hyagriv N., Frey, Heather, Rosen, Todd, Palatnik, Anna, Baker, Susan, August, Phyllis, Reddy, Uma M., Kinzler, Wendy, Su, Emily, Krishna, Iris, Nguyen, Nicki, Norton, Mary E., Skupski, Daniel, El-Sayed, Yasser Y., Ogunyemi, Dotum, Galis, Zorina S., Harper, Lorie, Ambalavanan, Namasivayam, Geller, Nancy L., Oparil, Suzanne, Cutter, Gary R., Andrews, William W.

“…Pregnant women with mild chronic hypertension were randomly assigned to receive medication targeting a normal blood pressure (<140/90 mm Hg) or to receive no…”
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Mechanisms of action of Bcl-2 family proteins by Shamas-Din, Aisha, Kale, Justin, Leber, Brian, Andrews, David W

“…The Bcl-2 family of proteins controls a critical step in commitment to apoptosis by regulating permeabilization of the mitochondrial outer membrane (MOM). The…”
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Targeting Antibiotic Tolerance, Pathogen by Pathogen by Meylan, Sylvain, Andrews, Ian W., Collins, James J.

“…Antibiotic tolerance, the capacity of genetically susceptible bacteria to survive the lethal effects of antibiotic treatment, plays a critical and…”
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Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes by Castro-Gomes, Thiago, Corrotte, Matthias, Tam, Christina, Andrews, Norma W

“…Eukaryotic cells rapidly repair wounds on their plasma membrane. Resealing is Ca(2+)-dependent, and involves exocytosis of lysosomes followed by massive…”
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A Deep Learning Approach to Antibiotic Discovery by Stokes, Jonathan M., Yang, Kevin, Swanson, Kyle, Jin, Wengong, Cubillos-Ruiz, Andres, Donghia, Nina M., MacNair, Craig R., French, Shawn, Carfrae, Lindsey A., Bloom-Ackermann, Zohar, Tran, Victoria M., Chiappino-Pepe, Anush, Badran, Ahmed H., Andrews, Ian W., Chory, Emma J., Church, George M., Brown, Eric D., Jaakkola, Tommi S., Barzilay, Regina, Collins, James J.

“…Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to discover new antibiotics. To address this challenge, we trained a deep…”
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Bidirectional and efficient conversion between microwave and optical light by Andrews, R. W., Peterson, R. W., Purdy, T. P., Cicak, K., Simmonds, R. W., Regal, C. A., Lehnert, K. W.

“…Converting low-frequency electrical signals into much higher-frequency optical signals has enabled modern communication networks to leverage the strengths of…”
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Laser Cooling of a Micromechanical Membrane to the Quantum Backaction Limit by Peterson, R W, Purdy, T P, Kampel, N S, Andrews, R W, Yu, P-L, Lehnert, K W, Regal, C A

“…The radiation pressure of light can act to damp and cool the vibrational motion of a mechanical resonator, but even if the light field has no thermal…”
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BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response by Sarosiek, Kristopher A., Chi, Xiaoke, Bachman, John A., Sims, Joshua J., Montero, Joan, Patel, Luv, Flanagan, Annabelle, Andrews, David W., Sorger, Peter, Letai, Anthony

“…Apoptosis is a highly regulated form of cell death that controls normal homeostasis as well as the antitumor activity of many chemotherapeutic agents…”
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Is serotonin an upper or a downer? The evolution of the serotonergic system and its role in depression and the antidepressant response by Andrews, Paul W, Bharwani, Aadil, Lee, Kyuwon R, Fox, Molly, Thomson, Jr, J Anderson

“…The role of serotonin in depression and antidepressant treatment remains unresolved despite decades of research. In this paper, we make three major claims…”
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MYC protein interactors in gene transcription and cancer by Lourenco, Corey, Resetca, Diana, Redel, Cornelia, Lin, Peter, MacDonald, Alannah S., Ciaccio, Roberto, Kenney, Tristan M. G., Wei, Yong, Andrews, David W., Sunnerhagen, Maria, Arrowsmith, Cheryl H., Raught, Brian, Penn, Linda Z.

“…The transcription factor and oncoprotein MYC is a potent driver of many human cancers and can regulate numerous biological activities that contribute to…”
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INFERENCE BASED ON CONDITIONAL MOMENT INEQUALITIES by Andrews, Donald W. K., Shi, Xiaoxia

“…In this paper, we propose an instrumental variable approach to constructing confidence sets (CS's) for the true parameter in models defined by conditional…”
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Reduced Sensitivity to Charge Noise in Semiconductor Spin Qubits via Symmetric Operation by Reed, M D, Maune, B M, Andrews, R W, Borselli, M G, Eng, K, Jura, M P, Kiselev, A A, Ladd, T D, Merkel, S T, Milosavljevic, I, Pritchett, E J, Rakher, M T, Ross, R S, Schmitz, A E, Smith, A, Wright, J A, Gyure, M F, Hunter, A T

“…We demonstrate improved operation of exchange-coupled semiconductor quantum dots by substantially reducing the sensitivity of exchange operations to charge…”
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BH3-only proteins: Orchestrators of apoptosis by Shamas-Din, Aisha, Brahmbhatt, Hetal, Leber, Brian, Andrews, David W.

“…The BH3-only proteins of Bcl-2 family are essential initiators of apoptosis that propagate extrinsic and intrinsic cell death signals. The interaction of…”
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Detection of Lysosomal Exocytosis by Surface Exposure of Lamp1 Luminal Epitopes by Andrews, Norma W

“…Elevation in the cytosolic Ca concentration triggers exocytosis of lysosomes in many cell types. This chapter describes a method to detect lysosomal exocytosis…”
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Inference for Parameters Defined by Moment Inequalities Using Generalized Moment Selection by Andrews, Donald W. K., Soares, Gustavo

“…The topic of this paper is inference in models in which parameters are defined by moment inequalities and/or equalities. The parameters may or may not be…”
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Generic results for establishing the asymptotic size of confidence sets and tests by Andrews, Donald W.K., Cheng, Xu, Guggenberger, Patrik

“…This paper provides a set of results that can be used to establish the asymptotic size and/or similarity in a uniform sense of confidence sets and tests. The…”
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Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance by Kale, Justin, Kutuk, Ozgur, Brito, Glauber Costa, Andrews, Tallulah S, Leber, Brian, Letai, Anthony, Andrews, David W

“…Akt is a pro‐survival kinase frequently activated in human cancers and is associated with more aggressive tumors that resist therapy. Here, we connect Akt…”
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A reference library for assigning protein subcellular localizations by image-based machine learning by Schormann, Wiebke, Hariharan, Santosh, Andrews, David W

“…Confocal micrographs of EGFP fusion proteins localized at key cell organelles in murine and human cells were acquired for use as subcellular localization…”
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Lipid droplet-associated proteins (LDAPs) are required for the dynamic regulation of neutral lipid compartmentation in plant cells by Gidda, Satinder K, Park, Sunjung, Pyc, Michal, Yurchenko, Olga, Cai, Yingqi, Wu, Peng, Andrews, David W, Chapman, Kent D, Dyer, John M, Mullen, Robert T

“…Eukaryotic cells compartmentalize neutral lipids into organelles called lipid droplets (LDs), and while much is known about the role of LDs in storing…”
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