Search Results - "Andrews, Tallulah S."

M3Drop: dropout-based feature selection for scRNASeq by Andrews, Tallulah S, Hemberg, Martin

“…Most genomes contain thousands of genes, but for most functional responses, only a subset of those genes are relevant. To facilitate many single-cell RNASeq…”
Get full text

Tutorial: guidelines for the computational analysis of single-cell RNA sequencing data by Andrews, Tallulah S., Kiselev, Vladimir Yu, McCarthy, Davis, Hemberg, Martin

“…Single-cell RNA sequencing (scRNA-seq) is a popular and powerful technology that allows you to profile the whole transcriptome of a large number of individual…”
Get full text

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance by Kale, Justin, Kutuk, Ozgur, Brito, Glauber Costa, Andrews, Tallulah S, Leber, Brian, Letai, Anthony, Andrews, David W

“…Akt is a pro‐survival kinase frequently activated in human cancers and is associated with more aggressive tumors that resist therapy. Here, we connect Akt…”
Get full text

Single‐Cell, Single‐Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity by Andrews, Tallulah S., Atif, Jawairia, Liu, Jeff C., Perciani, Catia T., Ma, Xue‐Zhong, Thoeni, Cornelia, Slyper, Michal, Eraslan, Gökcen, Segerstolpe, Asa, Manuel, Justin, Chung, Sai, Winter, Erin, Cirlan, Iulia, Khuu, Nicholas, Fischer, Sandra, Rozenblatt‐Rosen, Orit, Regev, Aviv, McGilvray, Ian D., Bader, Gary D., MacParland, Sonya A.

“…The critical functions of the human liver are coordinated through the interactions of hepatic parenchymal and non‐parenchymal cells. Recent advances in…”
Get full text

False signals induced by single-cell imputation [version 2; peer review: 4 approved] by Andrews, Tallulah S, Hemberg, Martin

“…Background: Single-cell RNA-seq is a powerful tool for measuring gene expression at the resolution of individual cells.  A challenge in the analysis of this…”
Get full text

Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cells by Kent, Gregory M., Atkins, Michael H., Lung, Bryan, Nikitina, Adele, Fernandes, Ian M., Kwan, Jamie J., Andrews, Tallulah S., MacParland, Sonya A., Keller, Gordon M., Gage, Blair K.

“…In mice, the first liver-resident macrophages, known as Kupffer cells (KCs), are thought to derive from yolk sac (YS) hematopoietic progenitors that are…”
Get full text

Challenges in unsupervised clustering of single-cell RNA-seq data by Kiselev, Vladimir Yu, Andrews, Tallulah S., Hemberg, Martin

“…Single-cell RNA sequencing (scRNA-seq) allows researchers to collect large catalogues detailing the transcriptomes of individual cells. Unsupervised clustering…”
Get full text

Identifying cell populations with scRNASeq by Andrews, Tallulah S., Hemberg, Martin

“…Single-cell RNASeq (scRNASeq) has emerged as a powerful method for quantifying the transcriptome of individual cells. However, the data from scRNASeq…”
Get full text

False signals induced by single-cell imputation [version 1; peer review: 4 approved with reservations] by Andrews, Tallulah S, Hemberg, Martin

“…Background: Single-cell RNASeq is a powerful tool for measuring gene expression at the resolution of individual cells.  A significant challenge in the analysis…”
Get full text

Tutorial: guidelines for annotating single-cell transcriptomic maps using automated and manual methods by Clarke, Zoe A., Andrews, Tallulah S., Atif, Jawairia, Pouyabahar, Delaram, Innes, Brendan T., MacParland, Sonya A., Bader, Gary D.

“…Single-cell transcriptomics can profile thousands of cells in a single experiment and identify novel cell types, states and dynamics in a wide variety of…”
Get full text

Untangling the web: The complex parenchymal-immune interface in endotoxemia by Andrews, Tallulah S., MacParland, Sonya A.

Get full text

A Spotlight on the Drivers of Inflammation in Acute Liver Failure by Andrews, Tallulah S., MacParland, Sonya A., Corey, Kathleen E., Malhi, Harmeet

Get full text

Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver by Andrews, Tallulah S., Nakib, Diana, Perciani, Catia T., Ma, Xue Zhong, Liu, Lewis, Winter, Erin, Camat, Damra, Chung, Sai W., Lumanto, Patricia, Manuel, Justin, Mangroo, Shantel, Hansen, Bettina, Arpinder, Bal, Thoeni, Cornelia, Sayed, Blayne, Feld, Jordan, Gehring, Adam, Gulamhusein, Aliya, Hirschfield, Gideon M., Ricciuto, Amanda, Bader, Gary D., McGilvray, Ian D., MacParland, Sonya

“…Primary sclerosing cholangitis (PSC) is an immune-mediated cholestatic liver disease for which there is an unmet need to understand the cellular composition of…”
Get full text

Publisher Correction: Challenges in unsupervised clustering of single-cell RNA-seq data by Kiselev, Vladimir Yu, Andrews, Tallulah S., Hemberg, Martin

“…During typesetting of this article, errors were inadvertently introduced to the hyperlinked URLs of some of the clustering tools in table 1 (Seurat, CIDR,…”
Get full text

GeneNet Toolbox for MATLAB: a flexible platform for the analysis of gene connectivity in biological networks by Taylor, Avigail, Steinberg, Julia, Andrews, Tallulah S, Webber, Caleb

“…We present GeneNet Toolbox for MATLAB (also available as a set of standalone applications for Linux). The toolbox, available as command-line or with a…”
Get full text