Search Results - "Andrews, PW"

Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue by Jevans, Benjamin, Cooper, Fay, Fatieieva, Yuliia, Gogolou, Antigoni, Kang, Yi-Ning, Restuadi, Restuadi, Moulding, Dale, Vanden Berghe, Pieter, Adameyko, Igor, Thapar, Nikhil, Andrews, Peter W, De Coppi, Paolo, Tsakiridis, Anestis, McCann, Conor J

“…Hirschsprung disease (HSCR) is a severe congenital disorder affecting 1:5000 live births. HSCR results from the failure of enteric nervous system (ENS)…”
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High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity by Borghese, Lodovica, Baker, Duncan, Närvä, Elisa, Harrison, Neil, Kitsberg, Danny, Cui, Wei, Maltby, Edna, Autio, Reija, Itskovitz-Eldor, Joseph, Hovatta, Outi, Benvenisty, Nissim, Kong, Lingjia, Rasool, Omid, Tuuri, Timo, Brüstle, Oliver, Dvorak, Petr, Rahkonen, Nelly, Andrews, Peter W, Lahesmaa, Riitta, Yli-Harja, Olli, Otonkoski, Timo, Moore, Harry D

“…Cultured human embryonic stem cells often acquire chromosomal abnormalities that could be detrimental in certain applications. Närvä et al . report the…”
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From teratocarcinomas to embryonic stem cells by Andrews, Peter W.

“…The recent derivation of human embryonic stem (ES) cell lines, together with results suggesting an unexpected degree of plasticity in later, seemingly more…”
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Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells by Andrews, Peter W, Draper, Jonathan S, Smith, Kath, Gokhale, Paul, Moore, Harry D, Maltby, Edna, Johnson, Julie, Meisner, Lorraine, Zwaka, Thomas P, Thomson, James A

“…We have observed karyotypic changes involving the gain of chromosome 17q in three independent human embryonic stem (hES) cell lines on five independent…”
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Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions by Hackland, James O.S., Frith, Tom J.R., Thompson, Oliver, Marin Navarro, Ana, Garcia-Castro, Martin I., Unger, Christian, Andrews, Peter W.

“…Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on…”
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LIF/STAT3 Signaling Fails to Maintain Self‐Renewal of Human Embryonic Stem Cells by Dahéron, Laurence, Opitz, Sarah L., Zaehres, Holm, Lensch, William M., Andrews, Peter W., Itskovitz‐Eldor, Joseph, Daley, George Q.

“…Murine embryonic stem (mES) cells remain undifferentiated in the presence of leukemia inhibitory factor (LIF), and activation of signal transducer and…”
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Gene Expression Patterns in Human Embryonic Stem Cells and Human Pluripotent Germ Cell Tumors by Sperger, Jamie M., Chen, Xin, Draper, Jonathan S., Antosiewicz, Jessica E., Chon, Chris H., Jones, Sunita B., Brooks, James D., Andrews, Peter W., Brown, Patrick O., Thomson, James A.

“…Remarkably little is known about the transcriptional profiles of human embryonic stem (ES) cells or the molecular mechanisms that underlie their pluripotency…”
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Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells by Enver, Tariq, Soneji, Shamit, Joshi, Chirag, Brown, John, Iborra, Francisco, Orntoft, Torben, Thykjaer, Thomas, Maltby, Edna, Smith, Kath, Dawud, Raed Abu, Jones, Mark, Matin, Maryam, Gokhale, Paul, Draper, Jonathan, Andrews, Peter W.

“…Human embryonic stem cell (HESC) lines vary in their characteristics and behaviour not only because they are derived from genetically outbred populations, but…”
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Toward a revised evolutionary adaptationist analysis of depression: the social navigation hypothesis by Watson, Paul J, Andrews, Paul W

“…Evolutionary biologists use Darwinian theory and functional design (“reverse engineering”) analyses, to develop and test hypotheses about the adaptive…”
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Specific Knockdown of Oct4 and beta 2-microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells by Matin, Maryam M, Walsh, James R, Gokhale, Paul J, Draper, Jonathan S, Bahrami, Ahmad R, Morton, Ian, Moore, Harry D, Andrews, Peter W

“…We have used RNA interference (RNAi) to downregulate beta 2-microglobulin and Oct4 in human embryonal carcinoma (hEC) cells and embryonic stem (hES) cells,…”
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Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin by Andrews, P W, Matin, M M, Bahrami, A R, Damjanov, I, Gokhale, P, Draper, J S

“…Embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and the malignant counterparts of embryonic stem (ES) cells derived from the inner cell…”
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Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells by Akopian, Veronika, Andrews, Peter W, Beil, Stephen, Benvenisty, Nissim, Brehm, Jennifer, Christie, Megan, Ford, Angela, Fox, Victoria, Gokhale, Paul J, Healy, Lyn, Holm, Frida, Hovatta, Outi, Knowles, Barbara B, Ludwig, Tenneille E, McKay, Ronald D. G, Miyazaki, Takamichi, Nakatsuji, Norio, Oh, Steve K. W, Pera, Martin F, Rossant, Janet, Stacey, Glyn N, Suemori, Hirofumi

“…There are many reports of defined culture systems for the propagation of human embryonic stem cells in the absence of feeder cell support, but no previous…”
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Preimplantation Human Embryos and Embryonic Stem Cells Show Comparable Expression of Stage‐Specific Embryonic Antigens by Henderson, J. K., Draper, J. S., Baillie, H. S., Fishel, S., Thomson, J. A., Moore, H., Andrews, P. W.

“…Cell‐surface antigens provide invaluable tools for the identification of cells and for the analysis of cell differentiation. In particular, stage‐specific…”
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Surface antigens of human embryonic stem cells: changes upon differentiation in culture by Draper, Jonathan S., Pigott, Christine, Thomson, James A., Andrews, Peter W.

“…We have analysed the surface antigen phenotype of a human embryonic stem (hES) cell line (H7) and the changes that occur upon differentiation induced by…”
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Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform by Stacey, Glyn N, Andrews, Peter W, Barbaric, Ivana, Boiers, Charlotta, Chandra, Amit, Cossu, Giulio, Csontos, Lynn, Frith, Thomas JR, Halliwell, Jason A, Hewitt, Zoe, McCall, Mark, Moore, Harry D, Parmar, Malin, Panico, M Beatrice, Pisupati, Venkat, Shichkin, Valentin P, Stacey, Alison R, Tedesco, Francesco S, Thompson, Oliver, Wagey, Ravenska

“…Human stem cells have the potential to transform medicine. However, hurdles remain to ensure that manufacturing processes produce safe and effective products…”
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Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development by SKOTHEIM, Rolf I, LIND, Guro E, LOTHE, Ragnhild A, MONNI, Outi, NESLAND, Jahn M, ABELER, Vera M, FOSSA, Sophie D, DUALE, Nur, BRUNBORG, Gunnar, KALLIONIEMI, Olli, ANDREWS, Peter W

“…Embryonal carcinoma is a histologic subgroup of testicular germ cell tumors (TGCTs), and its cells may follow differentiation lineages in a manner similar to…”
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Adaptationism--how to carry out an exaptationist program by Andrews, Paul W, Gangestad, Steven W, Matthews, Dan

“…Adaptationism is a research strategy that seeks to identify adaptations and the specific selective forces that drove their evolution in past environments…”
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Culture and characterization of human embryonic stem cells by Draper, Jonathan S, Moore, Harry D, Ruban, Ludmila N, Gokhale, Paul J, Andrews, Peter W

“…Human embryonic stem (ES) cells offer substantial opportunities for providing well-defined differentiated cells for drug discovery, toxicology, and…”
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Teratocarcinomas and human embryology: Pluripotent human EC cell lines by ANDREWS, PETER W.

“…The histogenesis of germ cell tumours (GCT) reflects the normal processes of gametogenesis, fertilisation and subsequent embryonic cell differentiation…”
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A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes by Hovatta, Outi, Jaconi, Marisa, Töhönen, Virpi, Béna, Frédérique, Gimelli, Stefania, Bosman, Alexis, Holm, Frida, Wyder, Stefan, Zdobnov, Evgeny M, Irion, Olivier, Andrews, Peter W, Antonarakis, Stylianos E, Zucchelli, Marco, Kere, Juha, Feki, Anis

“…The first Swiss human embryonic stem cell (hESC) line, CH-ES1, has shown features of a malignant cell line. It originated from the only single blastomere that…”
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