Search Results - "Andrews, Jared M"
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RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex
Published in Cell reports (Cambridge) (22-10-2019)“…Early B cell development is regulated by stage-specific transcription factors. PU.1, an ETS-family transcription factor, is essential for coordination of early…”
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Effects of valproic acid and dexamethasone administration on early bio-markers and gene expression profile in acute kidney ischemia-reperfusion injury in the rat
Published in PloS one (13-05-2015)“…Renal ischemia-reperfusion (IR) causes acute kidney injury (AKI) with high mortality and morbidity. The objective of this investigation was to ameliorate…”
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3
A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
Published in eLife (31-03-2017)“…Macrophages produce genotoxic agents, such as reactive oxygen and nitrogen species, that kill invading pathogens. Here we show that these agents activate the…”
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4
The role of neurosurgery in advancing pediatric CNS tumor care worldwide
Published in Brain & spine (01-01-2023)“…There is substantial inequity in survival outcomes for pediatric brain tumor patients residing in high-income countries (HICs) compared to low- and…”
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Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers
Published in EBioMedicine (01-09-2021)“…The most common B-cell cancers, chronic lymphocytic leukemia/lymphoma (CLL), follicular and diffuse large B-cell (FL, DLBCL) lymphomas, have distinct clinical…”
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Genotify: Fast, lightweight gene lookup and summarization
Published in Journal of open source software (01-01-2018)Get full text
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7
Epigenetic dynamics in normal and malignant B cells: die a hero or live to become a villain
Published in Current opinion in immunology (01-04-2019)“…•B cell development requires coordinated, sequential changes in epigenome landscapes.•3-D nuclear re-organization is essential for B cell…”
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Oncohistones and disrupted development in pediatric-type diffuse high-grade glioma
Published in Cancer and metastasis reviews (01-06-2023)“…Recurrent, clonal somatic mutations in histone H3 are molecular hallmarks that distinguish the genetic mechanisms underlying pediatric and adult high-grade…”
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Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM
Published in Nucleic acids research (20-09-2021)“…Abstract Epigenetic changes, such as aberrant DNA methylation, contribute to cancer clonal expansion and disease progression. However, identifying…”
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Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription
Published in Cell reports (Cambridge) (12-10-2021)“…Human respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections in the pediatric, elderly, and immunocompromised individuals…”
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Establishing Absolute Lymphocyte Count Thresholds for Further Review of Peripheral Blood Lymphocytosis to Judiciously Screen for Monoclonal B-Cell Populations in Older Adults
Published in American journal of clinical pathology (09-09-2019)“…Abstract Objectives Lymphocytosis may represent either a lymphoproliferative disorder (LPD) or a reactive process. The absolute lymphocyte count (ALC)…”
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Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
Published in EBioMedicine (01-08-2019)“…Treatment for Cutaneous T Cell Lymphoma (CTCL) is generally not curative. Therefore, selecting therapy that is effective and tolerable is critical to clinical…”
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A Seminested PCR Method for the Diagnosis of Invasive Fungal Infections in Combat Injured
Published in Open forum infectious diseases (01-06-2024)“…Among combat injured, invasive fungal infections (IFIs) result in significant morbidity. Cultures and histopathology are the primary diagnostic methods for…”
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14
Fat Intravasation from Intraosseous Flush and Infusion Procedures
Published in Prehospital emergency care (03-07-2015)“…Abstract Study hypothesis. The primary study objective was to delineate the procedural aspects of intraosseous (IO) infusions responsible for fat intravasation…”
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Using peripheral smear review, age and absolute lymphocyte count as predictors of abnormal peripheral blood lymphocytoses diagnosed by flow cytometry
Published in Leukemia & lymphoma (01-01-2008)“…Absolute lymphocytosis in the elderly raises the possibility of malignancy and generally warrants further investigation. To better correlate clinical variables…”
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A Semi-nested PCR Method for the Diagnosis of Invasive Fungal Infections in Combat Injured
Published in Open forum infectious diseases (13-02-2024)Get full text
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1021. Semi-nested Molecular Method for the Diagnosis of Invasive Fungal Infections in Combat Injured
Published in Open forum infectious diseases (27-11-2023)Get full text
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Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphomaResearch in context
Published in EBioMedicine (01-08-2019)“…Background: Treatment for Cutaneous T Cell Lymphoma (CTCL) is generally not curative. Therefore, selecting therapy that is effective and tolerable is critical…”
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Intraosseous hibernoma or unusual location of brown fat?
Published in Journal of hematopathology (01-09-2013)“…The hibernoma is a rare benign tumor of brown fat. It is most commonly found subcutaneously in the thigh, shoulder, and back of middle-aged adults…”
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Effects of Valproic Acid and Dexamethasone Administration on Early Bio-Markers and Gene Expression Profile in Acute Kidney Ischemia-Reperfusion Injury in the Rat: e0126622
Published in PloS one (01-05-2015)“…Renal ischemia-reperfusion (IR) causes acute kidney injury (AKI) with high mortality and morbidity. The objective of this investigation was to ameliorate…”
Get full text
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