Search Results - "Andrews, Jack P. M."

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses by Andrews, Jack P. M., Joshi, Shruti S., Tzolos, Evangelos, Syed, Maaz B., Cuthbert, Hayley, Crica, Livia E., Lozano, Neus, Okwelogu, Emmanuel, Raftis, Jennifer B., Bruce, Lorraine, Poland, Craig A., Duffin, Rodger, Fokkens, Paul H. B., Boere, A. John F., Leseman, Daan L. A. C., Megson, Ian L., Whitfield, Phil D., Ziegler, Kerstin, Tammireddy, Seshu, Hadjidemetriou, Marilena, Bussy, Cyrill, Cassee, Flemming R., Newby, David E., Kostarelos, Kostas, Miller, Mark R.

“…Graphene oxide nanomaterials are being developed for wide-ranging applications but are associated with potential safety concerns for human health. We conducted…”
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Ex vivo 18F-fluoride uptake and hydroxyapatite deposition in human coronary atherosclerosis by Moss, Alastair J., Sim, Alisia M., Adamson, Philip D., Seidman, Michael A., Andrews, Jack P. M., Doris, Mhairi K., Shah, Anoop S. V., BouHaidar, Ralph, Alcaide-Corral, Carlos J., Williams, Michelle C., Leipsic, Jonathon A., Dweck, Marc R., MacRae, Vicky E., Newby, David E., Tavares, Adriana A. S., Sellers, Stephanie L.

“…Early microcalcification is a feature of coronary plaques with an increased propensity to rupture and to cause acute coronary syndromes. In this ex vivo…”
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18F-fluoride PET/MR in cardiac amyloid: A comparison study with aortic stenosis and age- and sex-matched controls by Andrews, Jack P.M., Trivieri, Maria Giovanni, Everett, Russell, Spath, Nicholas, MacNaught, Gillian, Moss, Alastair J., Doris, Mhairi K., Pawade, Tania, van Beek, Edwin J.R., Lucatelli, Christophe, Newby, David E., Robson, Philip, Fayad, Zahi A., Dweck, Marc R.

“…Cardiac MR is widely used to diagnose cardiac amyloid, but cannot differentiate AL and ATTR subtypes: an important distinction given their differing treatments…”
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Cardiovascular 18F-fluoride positron emission tomography-magnetic resonance imaging: A comparison study by Andrews, Jack P.M., MacNaught, Gillian, Moss, Alastair J., Doris, Mhairi K., Pawade, Tania, Adamson, Philip D., van Beek, Edwin J.R., Lucatelli, Christophe, Lassen, Martin L., Robson, Philip M., Fayad, Zahi A., Kwiecinski, Jacek, Slomka, Piotr J., Berman, Daniel S., Newby, David E., Dweck, Marc R.

“…18F-Fluoride uptake denotes calcification activity in aortic stenosis and atherosclerosis. While PET/MR has several advantages over PET/CT, attenuation…”
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Implementation of an early rule-out pathway for myocardial infarction using a high-sensitivity cardiac troponin T assay by Sandeman, Dennis, Syed, Maaz B J, Kimenai, Dorien M, Lee, Kuan Ken, Anand, Atul, Joshi, Shruti S, Dinnel, Lorraine, Wenham, Philip R, Campbell, Ken, Jarvie, Mary, Galloway, Donna, Anderson, Mhairi, Roy, Bappa, Andrews, Jack P M, Strachan, Fiona E, Ferry, Amy V, Chapman, Andrew R, Elsby, Sarah, Francis, Mark, Cargill, Robert, Shah, Anoop S V, Mills, Nicholas L

“…ObjectivesPatients with suspected acute coronary syndrome and high-sensitivity cardiac troponin (hs-cTn) concentrations below the limit of detection at…”
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Early detection of valvular calcification by Andrews, Jack P. M., Dweck, Marc R.

“…The early stages of the formation of calcific nodules in the aortic valve can be detected by two-photon excited fluorescence microscopy…”
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New methods to image unstable atherosclerotic plaques by Andrews, Jack P.M., Fayad, Zahi A., Dweck, Marc R.

“…Atherosclerotic plaque rupture is the primary mechanism responsible for myocardial infarction and stroke, the top two killers worldwide. Despite being…”
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Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis by Suchacki, Karla J., Tavares, Adriana A. S., Mattiucci, Domenico, Scheller, Erica L., Papanastasiou, Giorgos, Gray, Calum, Sinton, Matthew C., Ramage, Lynne E., McDougald, Wendy A., Lovdel, Andrea, Sulston, Richard J., Thomas, Benjamin J., Nicholson, Bonnie M., Drake, Amanda J., Alcaide-Corral, Carlos J., Said, Diana, Poloni, Antonella, Cinti, Saverio, Macpherson, Gavin J., Dweck, Marc R., Andrews, Jack P. M., Williams, Michelle C., Wallace, Robert J., van Beek, Edwin J. R., MacDougald, Ormond A., Morton, Nicholas M., Stimson, Roland H., Cawthorn, William P.

“…Bone marrow adipose tissue (BMAT) comprises >10% of total adipose mass, yet unlike white or brown adipose tissues (WAT or BAT) its metabolic functions remain…”
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Effect of Denosumab or Alendronic Acid on the Progression of Aortic Stenosis: A Double-Blind Randomized Controlled Trial by Pawade, Tania A., Doris, Mhairi K., Bing, Rong, White, Audrey C., Forsyth, Laura, Evans, Emily, Graham, Catriona, Williams, Michelle C., van Beek, Edwin J.R., Fletcher, Alison, Adamson, Philip D., Andrews, Jack P.M., Cartlidge, Timothy R.G., Jenkins, William S.A., Syed, Maaz, Fujisawa, Takeshi, Lucatelli, Christophe, Fraser, William, Ralston, Stuart H., Boon, Nicholas, Prendergast, Bernard, Newby, David E., Dweck, Marc R.

“…Valvular calcification is central to the pathogenesis and progression of aortic stenosis, with preclinical and observational studies suggesting that bone…”
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Preclinical dosimetry models and the prediction of clinical doses of novel positron emission tomography radiotracers by Garrow, Adam A., Andrews, Jack P. M., Gonzalez, Zaniah N., Corral, Carlos A., Portal, Christophe, Morgan, Timaeus E. F., Walton, Tashfeen, Wilson, Ian, Newby, David E., Lucatelli, Christophe, Tavares, Adriana A. S.

“…Dosimetry models using preclinical positron emission tomography (PET) data are commonly employed to predict the clinical radiological safety of novel…”
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18F-GP1 Positron Emission Tomography and Bioprosthetic Aortic Valve Thrombus by Bing, Rong, Deutsch, Marcus-André, Sellers, Stephanie L., Corral, Carlos Alcaide, Andrews, Jack P.M., van Beek, Edwin J.R., Bleiziffer, Sabine, Burchert, Wolfgang, Clark, Tim, Dey, Damini, Friedrichs, Kai, Gummert, Jan F., Koglin, Norman, Leipsic, Jonathon A., Lindner, Oliver, MacAskill, Mark G., Milting, Hendrik, Pessotto, Renzo, Preuss, Rainer, Raftis, Jennifer B., Rudolph, Tanja K., Rudolph, Volker, Slomka, Piotr, Stephens, Andrew W., Tavares, Adriana, Tzolos, Evangelos, Weir, Nick, White, Audrey C., Williams, Michelle C., Zabel, Reinhard, Dweck, Marc R., Hugenberg, Verena, Newby, David E.

“…Bioprosthetic valve thrombosis may have implications for valve function and durability. Using a novel glycoprotein IIb/IIIa receptor radiotracer 18F-GP1, we…”
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Ticagrelor to Reduce Myocardial Injury in Patients With High-Risk Coronary Artery Plaque by Moss, Alastair J., Dweck, Marc R., Doris, Mhairi K., Andrews, Jack P.M., Bing, Rong, Forsythe, Rachael O., Cartlidge, Timothy R., Pawade, Tania A., Daghem, Marwa, Raftis, Jennifer B., Williams, Michelle C., van Beek, Edwin J.R., Forsyth, Laura, Lewis, Steff C., Lee, Robert J., Shah, Anoop S.V., Mills, Nicholas L., Newby, David E., Adamson, Philip D.

“…The goal of this study was to determine whether ticagrelor reduces high-sensitivity troponin I concentrations in patients with established coronary artery…”
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In Vivo Thrombosis Imaging in Patients Recovering from COVID-19 and Pulmonary Embolism by Bing, Rong, Andrews, Jack P M, Williams, Michelle C, van Beek, Edwin J R, Lucatelli, Christophe, MacNaught, Gillian, Clark, Tim, Koglin, Norman, Stephens, Andrew W, MacAskill, Mark G, Tavares, Adriana A S, Dhaliwal, Kevin, Dorward, David A, Lucas, Christopher D, Dweck, Marc R, Newby, David E

“…F-GP1 is a novel radiotracer that binds to the platelet glycoprotein IIb/IIIa receptor and can image in vivo venous and arterial thrombi, including deep vein…”
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Molecular Coronary Plaque Imaging Using 18F-Fluoride by Moss, Alastair J, Doris, Mhairi K, Andrews, Jack P M, Bing, Rong, Daghem, Marwa, van Beek, Edwin J R, syth, Laura, Shah, Anoop S V, Williams, Michelle C, Sellers, Stephanie, Leipsic, Jonathon, Dweck, Marc R, Parker, Richard A, Newby, David E, Adamson, Philip D

“…BACKGROUNDCoronary 18F-fluoride positron emission tomography identifies ruptured and high-risk atherosclerotic plaque. The optimal method to identify, to…”
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Progressive breathlessness following transcatheter aortic valve replacement by Andrews, Jack P M, Cruden, Nicholas L, Moss, Alastair J

“…: An 84-year-old man presented urgently to the cardiology clinic with rapid onset exertional dyspnoea while walking on the flat. Five months previously, he…”
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Non-invasive in vivo imaging of acute thrombosis: development of a novel factor XIIIa radiotracer by Andrews, Jack P M, Portal, Christophe, Walton, Tashfeen, Macaskill, Mark G, Hadoke, Patrick W F, Alcaide Corral, Carlos, Lucatelli, Christophe, Wilson, Simon, Wilson, Ian, MacNaught, Gillian, Dweck, Marc R, Newby, David E, Tavares, Adriana A S

“…Abstract Aims Cardiovascular thrombosis is responsible a quarter of deaths annually worldwide. Current imaging methods for cardiovascular thrombosis focus on…”
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Aortic valve stenosis-multimodality assessment with PET/CT and PET/MRI by Tzolos, Evangelos, Andrews, Jack Pm, Dweck, Marc R

“…Aortic valve disease is the most common form of heart valve disease in developed countries and a growing healthcare burden with an ageing population…”
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Disease Activity in Mitral Annular Calcification: A Multimodality Study by Massera, Daniele, Trivieri, Maria G., Andrews, Jack P.M., Sartori, Samantha, Abgral, Ronan, Chapman, Andrew R., Jenkins, William S.A., Vesey, Alex T., Doris, Mhairi K., Pawade, Tania A., Zheng, Kang H., Kizer, Jorge R., Newby, David E., Dweck, Marc R.

“…Background: Mitral annular calcification (MAC) is associated with cardiovascular events and mitral valve dysfunction. However, the underlying pathophysiology…”
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Coronary 18F-Fluoride Uptake and Progression of Coronary Artery Calcification by Doris, Mhairi K., Meah, Mohammed N., Moss, Alastair J., Andrews, Jack P.M., Bing, Rong, Gillen, Rebecca, Weir, Nick, Syed, Maaz, Daghem, Marwa, Shah, Anoop, Williams, Michelle C., van Beek, Edwin J.R., Forsyth, Laura, Dey, Damini, Slomka, Piotr J., Dweck, Marc R., Newby, David E., Adamson, Philip D.

“…Supplemental Digital Content is available in the text…”
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Coronary 18 F-Fluoride Uptake and Progression of Coronary Artery Calcification by Doris, Mhairi K, Meah, Mohammed N, Moss, Alastair J, Andrews, Jack P M, Bing, Rong, Gillen, Rebecca, Weir, Nick, Syed, Maaz, Daghem, Marwa, Shah, Anoop, Williams, Michelle C, van Beek, Edwin J R, Forsyth, Laura, Dey, Damini, Slomka, Piotr J, Dweck, Marc R, Newby, David E, Adamson, Philip D

“…Background Positron emission tomography (PET) using F-sodium fluoride ( F-fluoride) to detect microcalcification may provide insight into disease activity in…”
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