Search Results - "Andrews, J Owen"

A first order phase transition mechanism underlies protein aggregation in mammalian cells by Narayanan, Arjun, Meriin, Anatoli, Andrews, J Owen, Spille, Jan-Hendrik, Sherman, Michael Y, Cisse, Ibrahim I

“…The formation of misfolded protein aggregates is a hallmark of neurodegenerative diseases. The aggregate formation process exhibits an initial lag phase when…”
Get full text

RNA Polymerase II cluster dynamics predict mRNA output in living cells by Cho, Won-Ki, Jayanth, Namrata, English, Brian P, Inoue, Takuma, Andrews, J Owen, Conway, William, Grimm, Jonathan B, Spille, Jan-Hendrik, Lavis, Luke D, Lionnet, Timothée, Cisse, Ibrahim I

“…Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate…”
Get full text

RNA-Mediated Feedback Control of Transcriptional Condensates by Henninger, Jonathan E., Oksuz, Ozgur, Shrinivas, Krishna, Sagi, Ido, LeRoy, Gary, Zheng, Ming M., Andrews, J. Owen, Zamudio, Alicia V., Lazaris, Charalampos, Hannett, Nancy M., Lee, Tong Ihn, Sharp, Phillip A., Cissé, Ibrahim I., Chakraborty, Arup K., Young, Richard A.

“…Regulation of biological processes typically incorporates mechanisms that initiate and terminate the process and, where understood, these mechanisms often…”
Get full text