Search Results - "Andrew, Lubomira"
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The bivalent factor H binding protein meningococcal serogroup B vaccine elicits bactericidal antibodies against representative non-serogroup B meningococci
Published in Vaccine (29-10-2018)“…•FHbp expression is not restricted to serogroup B strains of N. meningitidis.•Protection against non-MenB strains by antibodies elicited by the MenB-FHbp…”
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Factor H binding protein (FHbp): An evaluation of genotypic diversity across Neisseria meningitidis serogroups
Published in Human vaccines & immunotherapeutics (31-12-2024)“…serogroups A, B, C, W, X, and Y cause invasive meningococcal disease (IMD) worldwide. Factor H binding protein (FHbp), a key meningococcal virulence factor, is…”
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Challenges for the evaluation of Staphylococcus aureus protein based vaccines: Monitoring antigenic diversity
Published in Human vaccines (01-01-2011)“…Clumping factors A (ClfA) and B (ClfB) are Staphylococcus aureus virulence proteins that are displayed on the cell surface of the organism and have potential…”
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Preclinical Immunogenicity and Efficacy of Optimized O25b O-Antigen Glycoconjugates To Prevent MDR ST131 E. coli Infections
Published in Infection and immunity (21-04-2022)“…Multivalent O-antigen polysaccharide glycoconjugate vaccines are under development to prevent invasive infections caused by pathogenic . Sequence type 131…”
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Bactericidal activity of sera from adolescents vaccinated with bivalent rLP2086 against meningococcal serogroup B outbreak strains from France
Published in Vaccine (13-03-2017)“…Highlights • French MnB outbreak strains were characterized by WGS and FHbp surface expression. • Bactericidal activity of sera from bivalent rLP2086 vaccinees…”
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Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease
Published in Vaccine (23-08-2010)“…Abstract Factor H binding proteins (fHBP), are bacterial surface proteins currently undergoing human clinical trials as candidate serogroup B Neisseria…”
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Sequence Diversity of the Factor H Binding Protein Vaccine Candidate in Epidemiologically Relevant Strains of Serogroup B Neisseria meningitidis
Published in The Journal of infectious diseases (01-08-2009)“…Background Recombinant forms of Neisseria meningitidis human factor H binding protein (fHBP) are undergoing clinical trials in candidate vaccines against…”
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Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States
Published in Vaccine (24-06-2011)“…Abstract Neisseria meningitidis (Nm) serogroups B, C and Y are the major causes of meningococcal diseases in the United States. NmB accounts for ∼1/3 of the…”
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Comparison of Phenotypic and Genotypic Approaches to Capsule Typing of Neisseria meningitidis by Use of Invasive and Carriage Isolate Collections
Published in Journal of clinical microbiology (01-01-2016)“…Neisseria meningitidis serogroup B (MnB) is a leading cause of bacterial meningitis; however, MnB is most commonly associated with asymptomatic carriage in the…”
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Development of a sequence-based in silico OspA typing method for Borrelia burgdorferi sensu lato
Published in Microbial genomics (01-05-2024)“…Lyme disease (LD), caused by spirochete bacteria of the genus , remains the most common vector-borne disease in the northern hemisphere. outer surface protein…”
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A Multi-country Evaluation of Neisseria meningitidis Serogroup B Factor H―Binding Proteins and Implications for Vaccine Coverage in Different Age Groups
Published in The Pediatric infectious disease journal (01-10-2013)“…Recombinant vaccines containing factor H-binding protein (fHBP) have been developed for the purpose of protection from invasive meningococcal serogroup B…”
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Distinct evolutionary patterns of Neisseria meningitidis serogroup B disease outbreaks at two universities in the USA
Published in Microbial genomics (01-04-2018)“…Neisseria meningitidis serogroup B (MnB) was responsible for two independent meningococcal disease outbreaks at universities in the USA during 2013. The first…”
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Prevalence and genetic diversity of candidate vaccine antigens among invasiveNeisseria meningitidisisolates in the United States
Published in Vaccine (24-06-2011)“…Neisseria meningitidis(Nm) serogroups B, C and Y are the major causes of meningococcal diseases in the United States. NmB accounts for ~1/3 of the disease but…”
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