Search Results - "Andrew, Aneesha A"

CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells by Kluesner, Mitchell G., Lahr, Walker S., Lonetree, Cara-lin, Smeester, Branden A., Qiu, Xiaohong, Slipek, Nicholas J., Claudio Vázquez, Patricia N., Pitzen, Samuel P., Pomeroy, Emily J., Vignes, Madison J., Lee, Samantha C., Bingea, Samuel P., Andrew, Aneesha A., Webber, Beau R., Moriarity, Branden S.

“…CRISPR-Cas9 cytidine and adenosine base editors (CBEs and ABEs) can disrupt genes without introducing double-stranded breaks by inactivating splice sites…”
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Correction of Fanconi Anemia Mutations Using Digital Genome Engineering by Sipe, Christopher J, Kluesner, Mitchell G, Bingea, Samuel P, Lahr, Walker S, Andrew, Aneesha A, Wang, Minjing, DeFeo, Anthony P, Hinkel, Timothy L, Laoharawee, Kanut, Wagner, John E, MacMillan, Margaret L, Vercellotti, Gregory M, Tolar, Jakub, Osborn, Mark J, McIvor, R Scott, Webber, Beau R, Moriarity, Branden S

“…Fanconi anemia (FA) is a rare genetic disease in which genes essential for DNA repair are mutated. Both the interstrand crosslink (ICL) and double-strand break…”
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