Search Results - "Andreu, Nuria"

Noninvasive biophotonic imaging for studies of infectious disease by Andreu, Nuria, Zelmer, Andrea, Wiles, Siouxsie

“…According to World Health Organization estimates, infectious organisms are responsible for approximately one in four deaths worldwide. Animal models play an…”
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Translation of a Leaderless Reporter Is Robust During Exponential Growth and Well Sustained During Stress Conditions in Mycobacterium tuberculosis by Grabowska, Anna D, Andreu, Nuria, Cortes, Teresa

“…expresses a large number of leaderless mRNA transcripts; these lack the 5' leader region, which usually contains the Shine-Dalgarno sequence required for…”
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An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome by Gomez-Gonzalez, Paula J., Andreu, Nuria, Phelan, Jody E., de Sessions, Paola Florez, Glynn, Judith R., Crampin, Amelia C., Campino, Susana, Butcher, Philip D., Hibberd, Martin L., Clark, Taane G.

“…Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis ( Mtb) , is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and…”
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Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease by Phelan, Jody, Gomez-Gonzalez, Paula Josefina, Andreu, Nuria, Omae, Yosuke, Toyo-Oka, Licht, Yanai, Hideki, Miyahara, Reiko, Nedsuwan, Supalert, de Sessions, Paola Florez, Campino, Susana, Sallah, Neneh, Parkhill, Julian, Smittipat, Nat, Palittapongarnpim, Prasit, Mushiroda, Taisei, Kubo, Michiaki, Tokunaga, Katsushi, Mahasirimongkol, Surakameth, Hibberd, Martin L., Clark, Taane G.

“…The genetics underlying tuberculosis (TB) pathophysiology are poorly understood. Human genome-wide association studies have failed so far to reveal…”
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Optimisation of bioluminescent reporters for use with mycobacteria by Andreu, Nuria, Zelmer, Andrea, Fletcher, Taryn, Elkington, Paul T, Ward, Theresa H, Ripoll, Jorge, Parish, Tanya, Bancroft, Gregory J, Schaible, Ulrich, Robertson, Brian D, Wiles, Siouxsie

“…Mycobacterium tuberculosis, the causative agent of tuberculosis, still represents a major public health threat in many countries. Bioluminescence, the…”
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Citizen science charts two major "stomatotypes" in the oral microbiome of adolescents and reveals links with habits and drinking water composition by Willis, Jesse R, González-Torres, Pedro, Pittis, Alexandros A, Bejarano, Luis A, Cozzuto, Luca, Andreu-Somavilla, Nuria, Alloza-Trabado, Miriam, Valentín, Antonia, Ksiezopolska, Ewa, Company, Carlos, Onywera, Harris, Montfort, Magda, Hermoso, Antonio, Iraola-Guzmán, Susana, Saus, Ester, Labeeuw, Annick, Carolis, Carlo, Hecht, Jochen, Ponomarenko, Julia, Gabaldón, Toni

“…The oral cavity comprises a rich and diverse microbiome, which plays important roles in health and disease. Previous studies have mostly focused on adult…”
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Rapid in vivo assessment of drug efficacy against Mycobacterium tuberculosis using an improved firefly luciferase by Andreu, Nuria, Zelmer, Andrea, Sampson, Samantha L, Ikeh, Melanie, Bancroft, Gregory J, Schaible, Ulrich E, Wiles, Siouxsie, Robertson, Brian D

“…In vivo experimentation is costly and time-consuming, and presents a major bottleneck in anti-tuberculosis drug development. Conventional methods rely on the…”
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Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors by Willis, Jesse R., Saus, Ester, Iraola-Guzmán, Susana, Ksiezopolska, Ewa, Cozzuto, Luca, Bejarano, Luis A., Andreu-Somavilla, Nuria, Alloza-Trabado, Miriam, Blanco, Andrea, Puig-Sola, Anna, Broglio, Elisabetta, Carolis, Carlo, Ponomarenko, Julia, Hecht, Jochen, Gabaldón, Toni

“…The relevance of the human oral microbiome to our understanding of human health has grown in recent years as microbiome studies continue to develop. Given the…”
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Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1 by Dierssen, Mara, Arqué, Gloria, McDonald, Jerome, Andreu, Nuria, Martínez-Cué, Carmen, Flórez, Jesús, Fillat, Cristina

“…DSCR1/ RCAN1 is a chromosome 21 gene found to be overexpressed in the brains of Down syndrome (DS) and postulated as a good candidate to contribute to mental…”
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Oncolytic adenoviruses armed with thymidine kinase can be traced by PET imaging and show potent antitumoural effects by ganciclovir dosing by Abate-Daga, Daniel, Andreu, Nuria, Camacho-Sánchez, Juan, Alemany, Ramon, Herance, Raúl, Millán, Olga, Fillat, Cristina

“…Replication-competent adenoviruses armed with thymidine kinase (TK) combine the concepts of virotherapy and suicide gene therapy. Moreover TK-activity can be…”
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Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges by Bofill-De Ros, Xavier, Santos, Mónica, Vila-Casadesús, Maria, Villanueva, Eneko, Andreu, Nuria, Dierssen, Mara, Fillat, Cristina

“…Down syndrome (DS) or trisomy 21 is the result of a genetic dosage imbalance that translates in a broad clinical spectrum. A major challenge in the study of DS…”
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Engagement of right temporal cortex during processing of linguistic context by Kircher, Tilo T.J, Brammer, Mick, Tous Andreu, Nuria, Williams, Steven C.R, McGuire, Philip K

“…Language processing involves the interplay of areas in both cerebral hemispheres. Whereas the left temporal lobe is necessary for most language tasks, the…”
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Oral microbiome in down syndrome and its implications on oral health by Willis, Jesse R., Iraola-Guzmán, Susana, Saus, Ester, Ksiezopolska, Ewa, Cozzuto, Luca, Bejarano, Luis A., Andreu-Somavilla, Nuria, Alloza-Trabado, Miriam, Puig-Sola, Anna, Blanco, Andrea, Broglio, Elisabetta, Carolis, Carlo, Hecht, Jochen, Ponomarenko, Julia, Gabaldón, Toni

“…Introduction: The oral cavity harbors an abundant and diverse microbial community (i.e. the microbiome), whose composition and roles in health and disease have…”
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Citizen-science based study of the oral microbiome in Cystic fibrosis and matched controls reveals major differences in diversity and abundance of bacterial and fungal species by Willis, Jesse R., Saus, Ester, Iraola-Guzmán, Susana, Cabello-Yeves, Elena, Ksiezopolska, Ewa, Cozzuto, Luca, Bejarano, Luis A., Andreu-Somavilla, Nuria, Alloza-Trabado, Miriam, Blanco, Andrea, Puig-Sola, Anna, Broglio, Elisabetta, Carolis, Carlo, Ponomarenko, Julia, Hecht, Jochen, Gabaldón, Toni

“…Introduction: Cystic fibrosis (CF) is an autosomal genetic disease, associated with the production of excessively thick mucosa and with life-threatening…”
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Triclosan-induced genes Rv1686c-Rv1687c and Rv3161c are not involved in triclosan resistance in Mycobacterium tuberculosis by Gomez, Andromeda, Andreu, Núria, Ferrer-Navarro, Mario, Yero, Daniel, Gibert, Isidre

“…A key issue towards developing new chemotherapeutic approaches to fight Mycobacterium tuberculosis is to understand the mechanisms underlying drug resistance…”
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A novel Wiskott-Aldrich syndrome protein (WASP) complex mutation identified in a WAS patient results in an aberrant product at the C-terminus from two transcripts with unusual polyA signals by Andreu, Nuria, García-Rodríguez, Maricruz, Volpini, Victor, Frecha, Cecilia, Molina, Ignacio J, Fontan, Gumersindo, Fillat, Cristina

“…Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder characterized by immunodeficiency, thrombocytopenia and eczema. A broad spectrum of mutations…”
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El uso de Emoticonos como elemento de Comunicación. (EMO-TIC) by Andreu Ato, Nuria, Díez González, María Carmen

“…En los últimos años, la comunicación digital o vía ordenador (CVO) ha modificado en gran medida los mecanismos comunicativos, pues la comunicación…”
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Cell population heterogeneity in Mycobacterium tuberculosis H37Rv by Andreu, Núria, Gibert, Isidre

“…Summary The laboratory strain H37Rv represents one of the most commonly used strains in the study of Mycobacterium tuberculosis . Despite the apparent…”
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Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis by Andreu, Nuria, Phelan, Jody, de Sessions, Paola F., Cliff, Jacqueline M., Clark, Taane G., Hibberd, Martin L.

“…Macrophages play an essential role in the early immune response to Mycobacterium tuberculosis and are the cell type preferentially infected in vivo . Primary…”
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Targeting Dyrk1A with AAVshRNA Attenuates Motor Alterations in TgDyrk1A, a Mouse Model of Down Syndrome by Ortiz-Abalia, Jon, Sahún, Ignasi, Altafaj, Xavier, Andreu, Núria, Estivill, Xavier, Dierssen, Mara, Fillat, Cristina

“…Genetic-dissection studies carried out with Down syndrome (DS) murine models point to the critical contribution of Dyrk1A overexpression to the motor…”
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