Search Results - "Andreas Woerner"

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA by Woerner, Andreas C., Frottin, Frédéric, Hornburg, Daniel, Feng, Li R., Meissner, Felix, Patra, Maria, Tatzelt, Jörg, Mann, Matthias, Winklhofer, Konstanze F., Hartl, F. Ulrich, Hipp, Mark S.

“…Amyloid-like protein aggregation is associated with neurodegeneration and other pathologies. The nature of the toxic aggregate species and their mechanism of…”
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Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions by Olzscha, Heidi, Schermann, Sonya M., Woerner, Andreas C., Pinkert, Stefan, Hecht, Michael H., Tartaglia, Gian G., Vendruscolo, Michele, Hayer-Hartl, Manajit, Hartl, F. Ulrich, Vabulas, R. Martin

“…Protein aggregation is linked with neurodegeneration and numerous other diseases by mechanisms that are not well understood. Here, we have analyzed the…”
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A protein quality control pathway regulated by linear ubiquitination by van Well, Eva M, Bader, Verian, Patra, Maria, Sánchez‐Vicente, Ana, Meschede, Jens, Furthmann, Nikolas, Schnack, Cathrin, Blusch, Alina, Longworth, Joseph, Petrasch‐Parwez, Elisabeth, Mori, Kohji, Arzberger, Thomas, Trümbach, Dietrich, Angersbach, Lena, Showkat, Cathrin, Sehr, Dominik A, Berlemann, Lena A, Goldmann, Petra, Clement, Albrecht M, Behl, Christian, Woerner, Andreas C, Saft, Carsten, Wurst, Wolfgang, Haass, Christian, Ellrichmann, Gisa, Gold, Ralf, Dittmar, Gunnar, Hipp, Mark S, Hartl, F Ulrich, Tatzelt, Jörg, Winklhofer, Konstanze F

“…Neurodegenerative diseases are characterized by the accumulation of misfolded proteins in the brain. Insights into protein quality control mechanisms to…”
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The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication by Resenberger, Ulrike K, Harmeier, Anja, Woerner, Andreas C, Goodman, Jessica L, Müller, Veronika, Krishnan, Rajaraman, Vabulas, R Martin, Kretzschmar, Hans A, Lindquist, Susan, Hartl, F Ulrich, Multhaup, Gerd, Winklhofer, Konstanze F, Tatzelt, Jörg

“…Formation of aberrant protein conformers is a common pathological denominator of different neurodegenerative disorders, such as Alzheimer's disease or prion…”
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Estimating the prevalence of paediatric chronic pain in Switzerland: an online survey among paediatricians by Koechlin, Helen, Locher, Cosima, Carlander, Maria, Kossowsky, Joe, Woerner, Andreas, Dratva, Julia

“…BACKGROUND: Chronic pain is a frequent complaint in children and adolescents, with great international variation in prevalence. Paediatricians are usually the…”
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Biologic disease modifying antirheumatic drugs and Janus kinase inhibitors in paediatric rheumatology - what we know and what we do not know from randomized controlled trials by Welzel, Tatjana, Winskill, Carolyn, Zhang, Nancy, Woerner, Andreas, Pfister, Marc

“…Biologic disease modifying antirheumatic drugs (bDMARDs) and Janus Kinase (JAK) inhibitors are prescribed in adult and paediatric rheumatology. Due to…”
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His75−Asp97 Cluster in Green Proteorhodopsin by Hempelmann, Franziska, Hölper, Soraya, Verhoefen, Mirka-Kristin, Woerner, Andreas C, Köhler, Thomas, Fiedler, Sarah-Anna, Pfleger, Nicole, Wachtveitl, Josef, Glaubitz, Clemens

“…The proteorhodopsin (PR) family found in bacteria near the ocean’s surface consists of hundreds of PR variants color-tuned to their environment. PR contains a…”
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Correction to: Biologic disease modifying antirheumatic drugs and Janus kinase inhibitors in paediatric rheumatology – what we know and what we do not know from randomized controlled trials by Welzel, Tatjana, Winskill, Carolyn, Zhang, Nancy, Woerner, Andreas, Pfister, Marc

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Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland by Schlapbach, Luregn J, Andre, Maya C, Grazioli, Serge, Schöbi, Nina, Ritz, Nicole, Aebi, Christoph, Agyeman, Philipp, Albisetti, Manuela, Bailey, Douggl G N, Berger, Christoph, Blanchard-Rohner, Géraldine, Bressieux-Degueldre, Sabrina, Hofer, Michael, L'Huillier, Arnaud G, Marston, Mark, Meyer Sauteur, Patrick M, Pachlopnik Schmid, Jana, Perez, Marie-Helene, Rogdo, Bjarte, Trück, Johannes, Woerner, Andreas, Wütz, Daniela, Zimmermann, Petra, Levin, Michael, Whittaker, Elizabeth, Rimensberger, Peter C

“…Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome…”
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Real-Life Indications of Interleukin-1 Blocking Agents in Hereditary Recurrent Fevers: Data From the JIRcohort and a Literature Review by Vinit, Caroline, Georgin-Lavialle, Sophie, Theodoropoulou, Aikaterini, Barbier, Catherine, Belot, Alexandre, Mejbri, Manel, Pillet, Pascal, Pachlopnik, Jana, Poignant, Sylvaine, Rebelle, Charlotte, Woerner, Andreas, Koné-Paut, Isabelle, Hentgen, Véronique

“…Interleukin (IL)-1 inhibitors represent the main treatment in patients with colchicine-resistant/intolerant familial Mediterranean fever (crFMF), mevalonate…”
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Prospective study to characterize adalimumab exposure in pediatric patients with rheumatic diseases by Welzel, Tatjana, Golhen, Klervi, Atkinson, Andrew, Gotta, Verena, Ternant, David, Kuemmerle-Deschner, Jasmin B, Michler, Christine, Koch, Gilbert, van den Anker, Johannes N, Pfister, Marc, Woerner, Andreas

“…In pediatric rheumatic diseases (PRD), adalimumab is dosed using fixed weight-based bands irrespective of methotrexate co-treatment, disease activity (DA) or…”
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Voltage- and pH-Dependent Changes in Vectoriality of Photocurrents Mediated by Wild-type and Mutant Proteorhodopsins upon Expression in Xenopus Oocytes by Lörinczi, Éva, Verhoefen, Mirka-Kristin, Wachtveitl, Josef, Woerner, Andreas C., Glaubitz, Clemens, Engelhard, Martin, Bamberg, Ernst, Friedrich, Thomas

“…Proteorhodopsin (PR), a light-driven proton pump from marine proteobacteria, exhibits photocycle characteristics similar to bacteriorhodopsin (BR) at neutral…”
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Current practice of transitional care for adolescents and young adults in Swiss paediatric and adult rheumatology centres by Berben, Lut, Sigg, Nora, Daly, Mary Louise, Bachmann, Stefan, Baer, Walter, Berthet, Gérald, Bolt, Isabel, Dan, Diana, Enderlin Steiger, Susanna, Fröhlich, Johannes, Hasler, Paul, Hofer, Michaël, Huemer, Christian, Kaiser, Daniela, Marcoli, Natalie, Palmer Sarott, Seraina, Rottländer, Yella, Schmid, Gernot, Soennichsen, Christa, Strahm Furler, Laura, Vanoni, Federica, Wildi, Lukas, Daikeler, Thomas, Woerner, Andreas

“…About half of all children with rheumatic diseases need continuous medical care during adolescence and adulthood. A good transition into adult rheumatology is…”
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Characterisation of Schiff base and chromophore in green proteorhodopsin by solid-state NMR by Pfleger, Nicole, Lorch, Mark, Woerner, Andreas C, Shastri, Sarika, Glaubitz, Clemens

“…The proteorhodopsin family consists of hundreds of homologous retinal containing membrane proteins found in bacteria in the photic zone of the oceans. They are…”
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Vaccination completeness in children with rheumatic diseases: A longitudinal, observational multicenter cohort study in Switzerland by Welzel, Tatjana, Kuemmerle-Deschner, Jasmin, Sluka, Constantin, Carlomagno, Raffaella, Cannizzaro Schneider, Elvira, Kaiser, Daniela, Hofer, Michael, Hentgen, Veronique, Woerner, Andreas

“…Introduction Children with pediatric inflammatory rheumatic diseases (PRD) have an increased infection risk. Vaccinations are effective to avoid…”
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Photoisomerization in Proteorhodopsin Mutant D97N by Lenz, Martin O., Woerner, Andreas C., Glaubitz, Clemens, Wachtveitl, Josef

“…The first steps of the photocycle of the D97N mutant of proteorhodopsin (PR) have been investigated by means of ultrafast transient absorption spectroscopy. A…”
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X-Linked Lymphoproliferative Disease Mimicking Multisystem Inflammatory Syndrome in Children—A Case Report by Prader, Seraina, Ritz, Nicole, Baleydier, Frédéric, Andre, Maya C., Stähli, Noémie, Schmid, Kevin, Schmid, Hanna, Woerner, Andreas, Diesch, Tamara, Meyer Sauteur, Patrick M., Trück, Johannes, Gebistorf, Fabienne, Opitz, Lennart, Killian, Michael P., Marchetti, Tommaso, Vavassori, Stefano, Blanchard-Rohner, Géraldine, Mc Lin, Valerie, Grazioli, Serge, Pachlopnik Schmid, Jana

“…Most children with a SARS-CoV-2 infection are asymptomatic or exhibit mild symptoms. However, a small number of children develop features of substantial…”
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Immune response to influenza vaccination in children treated with methotrexate or/and tumor necrosis factor-α inhibitors by Woerner, Andreas, Sauvain, Marie-Josèphe, Aebi, Christoph, Otth, Margrit, Bolt, Isabel B.

“…In children treated with immunosuppressive medication such as methotrexate and tumor necrosis factor-alpha (TNF-α) inhibitors, additional immunizations are…”
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Infections in Children Treated With Biological Agents by WOERNER, Andreas, RITZ, Nicole

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Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis by Schulert, Grant S., Minoia, Francesca, Bohnsack, John, Cron, Randy Q., Hashad, Soah, KonÉ‐Paut, Isabelle, Kostik, Mikhail, Lovell, Daniel, Maritsi, Despoina, Nigrovic, Peter A., Pal, Priyankar, Ravelli, Angelo, Shimizu, Masaki, Stanevicha, Valda, Vastert, Sebastiaan, Woerner, Andreas, Benedetti, Fabrizio, Grom, Alexei A.

“…Objective To assess performance of the 2016 macrophage activation syndrome (MAS) classification criteria for patients with systemic juvenile idiopathic…”
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