Search Results - "Andreas M. Zeiher"

Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19) by Puntmann, Valentina O, Carerj, M Ludovica, Wieters, Imke, Fahim, Masia, Arendt, Christophe, Hoffmann, Jedrzej, Shchendrygina, Anastasia, Escher, Felicitas, Vasa-Nicotera, Mariuca, Zeiher, Andreas M, Vehreschild, Maria, Nagel, Eike

“…Coronavirus disease 2019 (COVID-19) continues to cause considerable morbidity and mortality worldwide. Case reports of hospitalized patients suggest that…”
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Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts by Nicin, Luka, Abplanalp, Wesley Tyler, Mellentin, Hannah, Kattih, Badder, Tombor, Lukas, John, David, Schmitto, Jan D, Heineke, Jörg, Emrich, Fabian, Arsalan, Mani, Holubec, Tomas, Walther, Thomas, Zeiher, Andreas M, Dimmeler, Stefanie

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Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure by Abplanalp, Wesley Tyler, Cremer, Sebastian, John, David, Hoffmann, Jedrzej, Schuhmacher, Bianca, Merten, Maximillian, Rieger, Michael A., Vasa-Nicotera, Mariuca, Zeiher, Andreas M., Dimmeler, Stefanie

“…Clonal hematopoiesis driven by mutations of DNMT3A (DNA methyltransferase 3a) is associated with increased incidence of cardiovascular disease and poor…”
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Identification and Characterization of Hypoxia-Regulated Endothelial Circular RNA by Boeckel, Jes-Niels, Jaé, Nicolas, Heumüller, Andreas W, Chen, Wei, Boon, Reinier A, Stellos, Konstantinos, Zeiher, Andreas M, John, David, Uchida, Shizuka, Dimmeler, Stefanie

“…RATIONALE:Circular RNAs (circRNAs) are noncoding RNAs generated by back splicing. Back splicing has been considered a rare event, but recent studies suggest…”
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SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes by Bojkova, Denisa, Wagner, Julian U G, Shumliakivska, Mariana, Aslan, Galip S, Saleem, Umber, Hansen, Arne, Luxán, Guillermo, Günther, Stefan, Pham, Minh Duc, Krishnan, Jaya, Harter, Patrick N, Ermel, Utz H, Frangakis, Achilleas S, Milting, Hendrik, Zeiher, Andreas M, Klingel, Karin, Cinatl, Jindrich, Dendorfer, Andreas, Eschenhagen, Thomas, Tschöpe, Carsten, Ciesek, Sandra, Dimmeler, Stefanie

“…Abstract Aims Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has emerged as a global pandemic…”
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Clonal haematopoiesis in chronic ischaemic heart failure: prognostic role of clone size for DNMT3A- and TET2-driver gene mutations by Assmus, Birgit, Cremer, Sebastian, Kirschbaum, Klara, Culmann, David, Kiefer, Katharina, Dorsheimer, Lena, Rasper, Tina, Abou-El-Ardat, Khalil, Herrmann, Eva, Berkowitsch, Alexander, Hoffmann, Jedrzej, Seeger, Florian, Mas-Peiro, Silvia, Rieger, Michael A, Dimmeler, Stefanie, Zeiher, Andreas M

“…Abstract Aims Somatic mutations of the epigenetic regulators DNMT3A and TET2 causing clonal expansion of haematopoietic cells (clonal haematopoiesis; CH) were…”
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Role of Dicer and Drosha for Endothelial MicroRNA Expression and Angiogenesis by Kuehbacher, Angelika, Urbich, Carmen, Zeiher, Andreas M, Dimmeler, Stefanie

“…MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by binding to the cellular transcript leading to translational repression or…”
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Laminar Shear Stress Inhibits Endothelial Cell Metabolism via KLF2-Mediated Repression of PFKFB3 by Doddaballapur, Anuradha, Michalik, Katharina M, Manavski, Yosif, Lucas, Tina, Houtkooper, Riekelt H, You, Xintian, Chen, Wei, Zeiher, Andreas M, Potente, Michael, Dimmeler, Stefanie, Boon, Reinier A

“…OBJECTIVE—Cellular metabolism was recently shown to regulate endothelial cell phenotype profoundly. Whether the atheroprotective biomechanical stimulus…”
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Inhibition of MicroRNA-92a Protects Against Ischemia/Reperfusion Injury in a Large-Animal Model by Hinkel, Rabea, Penzkofer, Daniela, Zühlke, Stefanie, Fischer, Ariane, Husada, Wira, Xu, Quan-Fu, Baloch, Elisabeth, van Rooij, Eva, Zeiher, Andreas M., Kupatt, Christian, Dimmeler, Stefanie

“…BACKGROUND—MicroRNAs (miRs) are small noncoding RNAs that posttranscriptionally control gene expression. Small-animal studies suggest that miRs might offer…”
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Characterization of levels and cellular transfer of circulating lipoprotein-bound microRNAs by Wagner, Jasmin, Riwanto, Meliana, Besler, Christian, Knau, Andrea, Fichtlscherer, Stephan, Röxe, Tino, Zeiher, Andreas M, Landmesser, Ulf, Dimmeler, Stefanie

“…MicroRNAs are important intracellular regulators of gene expression, but also circulate in the blood being protected by extracellular vesicles, proteins, or…”
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Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs by Hergenreider, Eduard, Heydt, Susanne, Tréguer, Karine, Boettger, Thomas, Horrevoets, Anton J. G., Zeiher, Andreas M., Scheffer, Margot P., Frangakis, Achilleas S., Yin, Xiaoke, Mayr, Manuel, Braun, Thomas, Urbich, Carmen, Boon, Reinier A., Dimmeler, Stefanie

“…The shear-responsive transcription factor Krüppel-like factor 2 (KLF2) is a critical regulator of endothelial gene expression patterns induced by…”
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Cell-Based Therapy of Myocardial Infarction by Dimmeler, Stefanie, Burchfield, Jana, Zeiher, Andreas M

“…Cell-based therapy is a promising option for treatment of ischemic diseases. Several cell types have experimentally been shown to increase the functional…”
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Transcoronary Concentration Gradients of Circulating MicroRNAs by DE ROSA, Salvatore, FICHTLSCHERER, Stephan, LEHMANN, Ralf, ASSMUS, Birgit, DIMMELER, Stefanie, ZEIHER, Andreas M

“…Circulating levels of microRNA (miR) have been proposed as biomarkers for cardiovascular disease. To identify the heart as a potential source for miRs released…”
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MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice by Bonauer, Angelika, Carmona, Guillaume, Iwasaki, Masayoshi, Mione, Marina, Koyanagi, Masamichi, Fischer, Ariane, Burchfield, Jana, Fox, Henrik, Doebele, Carmen, Ohtani, Kisho, Chavakis, Emmanouil, Potente, Michael, Tjwa, Marc, Urbich, Carmen, Zeiher, Andreas M, Dimmeler, Stefanie

“…MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression by binding to target messenger RNAs (mRNAs), leading to translational repression or…”
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Oxidative stress and epigenetic regulation in ageing and age-related diseases by Cencioni, Chiara, Spallotta, Francesco, Martelli, Fabio, Valente, Sergio, Mai, Antonello, Zeiher, Andreas M, Gaetano, Carlo

“…Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, elderly people are increasing. This trend is particularly…”
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Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization by Manavski, Yosif, Lucas, Tina, Glaser, Simone F, Dorsheimer, Lena, Günther, Stefan, Braun, Thomas, Rieger, Michael A, Zeiher, Andreas M, Boon, Reinier A, Dimmeler, Stefanie

“…RATIONALE:Vascularization is critical to maintain organ function. Although many molecular pathways were shown to control vessel growth, the genuine process of…”
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Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells by Doebele, Carmen, Bonauer, Angelika, Fischer, Ariane, Scholz, Alexander, Reiss, Yvonne, Urbich, Carmen, Hofmann, Wolf-Karsten, Zeiher, Andreas M., Dimmeler, Stefanie

“…MicroRNAs are endogenously expressed small noncoding RNAs that regulate gene expression on the posttranscriptional level. The miR-17-92 cluster (encoding…”
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MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation by Boon, Reinier A, Seeger, Timon, Heydt, Susanne, Fischer, Ariane, Hergenreider, Eduard, Horrevoets, Anton J.G, Vinciguerra, Manlio, Rosenthal, Nadia, Sciacca, Sergio, Pilato, Michele, van Heijningen, Paula, Essers, Jeroen, Brandes, Ralf P, Zeiher, Andreas M, Dimmeler, Stefanie

“…RATIONALE:Aging represents a major risk factor for coronary artery disease and aortic aneurysm formation. MicroRNAs (miRs) have emerged as key regulators of…”
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MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A by Urbich, Carmen, Kaluza, David, Frömel, Timo, Knau, Andrea, Bennewitz, Katrin, Boon, Reinier A., Bonauer, Angelika, Doebele, Carmen, Boeckel, Jes-Niels, Hergenreider, Eduard, Zeiher, Andreas M., Kroll, Jens, Fleming, Ingrid, Dimmeler, Stefanie

“…MicroRNAs (miRs) are small RNAs that regulate gene expression at the posttranscriptional level. miR-27 is expressed in endothelial cells, but the specific…”
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Quantification of circulating endothelial progenitor cells using the modified ISHAGE protocol by Schmidt-Lucke, Caroline, Fichtlscherer, Stephan, Aicher, Alexandra, Tschöpe, Carsten, Schultheiss, Heinz-Peter, Zeiher, Andreas M, Dimmeler, Stefanie

“…Circulating endothelial progenitor cells (EPC), involved in endothelial regeneration, neovascularisation, and determination of prognosis in cardiovascular…”
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