Search Results - "Andreas, Schneeweiss"

Atezolizumab and nab-Paclitaxel in Advanced Triple-Negative Breast Cancer: Biomarker Evaluation of the IMpassion130 Study by Emens, Leisha A, Molinero, Luciana, Loi, Sherene, Rugo, Hope S, Schneeweiss, Andreas, Diéras, Véronique, Iwata, Hiroji, Barrios, Carlos H, Nechaeva, Marina, Nguyen-Duc, Anh, Chui, Stephen Y, Husain, Amreen, Winer, Eric P, Adams, Sylvia, Schmid, Peter

“…Abstract Background Understanding the impact of the tumor immune microenvironment and BRCA1/2-related DNA repair deficiencies on the clinical activity of…”
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Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: A randomized controlled trial by Schmidt, Martina E., Wiskemann, Joachim, Armbrust, Petra, Schneeweiss, Andreas, Ulrich, Cornelia M., Steindorf, Karen

“…Multiple exercise interventions have shown beneficial effects on fatigue and quality of life (QoL) in cancer patients, but various psychosocial interventions…”
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A plasma metabolite panel as biomarkers for early primary breast cancer detection by Yuan, Baowen, Schafferer, Simon, Tang, Qiuqiong, Scheffler, Matthias, Nees, Juliane, Heil, Jörg, Schott, Sarah, Golatta, Michael, Wallwiener, Markus, Sohn, Christof, Koal, Therese, Wolf, Barbara, Schneeweiß, Andreas, Burwinkel, Barbara

“…In recent years, metabolites have attracted substantial attention as promising novel biomarkers of various diseases. However, breast cancer plasma metabolite…”
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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study by Swain, Sandra M, Dr, Kim, Sung-Bae, MD, Cortés, Javier, MD, Ro, Jungsil, MD, Semiglazov, Vladimir, MD, Campone, Mario, MD, Ciruelos, Eva, MD, Ferrero, Jean-Marc, MD, Schneeweiss, Andreas, MD, Knott, Adam, PhD, Clark, Emma, MSc, Ross, Graham, FFPM, Benyunes, Mark C, MD, Baselga, José, MD

“…Summary Background CLEOPATRA is a phase 3 study to compare the efficacy and safety of pertuzumab, trastuzumab, and docetaxel with placebo, trastuzumab, and…”
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Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs by Pein, Maren, Insua-Rodríguez, Jacob, Hongu, Tsunaki, Riedel, Angela, Meier, Jasmin, Wiedmann, Lena, Decker, Kristin, Essers, Marieke A. G., Sinn, Hans-Peter, Spaich, Saskia, Sütterlin, Marc, Schneeweiss, Andreas, Trumpp, Andreas, Oskarsson, Thordur

“…Metastatic colonization relies on interactions between disseminated cancer cells and the microenvironment in secondary organs. Here, we show that disseminated…”
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Circulating Tumor Cells Predict Survival in Early Average-to-High Risk Breast Cancer Patients by RACK, Brigitte, SCHINDLBECK, Christian, FEHM, Tanja, SCHNEEWEISS, Andreas, LICHTENEGGER, Werner, BECKMANN, Matthias W, FRIESE, Klaus, PANTEL, Klaus, JANNI, Wolfgang, JÜCKSTOCK, Julia, ANDERGASSEN, Ulrich, HEPP, Philip, ZWINGERS, Thomas, FRIEDL, Thomas W. P, LORENZ, Ralf, TESCH, Hans, FASCHING, Peter A

“…Circulating tumor cells (CTCs) have been shown to predict reduced survival outcomes in metastatic breast cancer. CTCs were analyzed in 2026 patients with early…”
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Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial by Stevic, Ines, Müller, Volkmar, Weber, Karsten, Fasching, Peter A, Karn, Thomas, Marmé, Frederic, Schem, Christian, Stickeler, Elmar, Denkert, Carsten, van Mackelenbergh, Marion, Salat, Christoph, Schneeweiss, Andreas, Pantel, Klaus, Loibl, Sibylle, Untch, Michael, Schwarzenbach, Heidi

“…The focus of this study is to identify particular microRNA (miRNA) signatures in exosomes derived from plasma of 435 human epidermal growth factor receptor 2…”
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Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial by von Minckwitz, Gunter, Prof, Schneeweiss, Andreas, Prof, Loibl, Sibylle, Prof, Salat, Christoph, MD, Denkert, Carsten, Prof, Rezai, Mahdi, Prof, Blohmer, Jens U, Prof, Jackisch, Christian, Prof, Paepke, Stefan, MD, Gerber, Bernd, Prof, Zahm, Dirk M, MD, Kümmel, Sherko, MD, Eidtmann, Holger, MD, Klare, Peter, MD, Huober, Jens, Prof, Costa, Serban, Prof, Tesch, Hans, Prof, Hanusch, Claus, MD, Hilfrich, Jörn, Prof, Khandan, Fariba, MD, Fasching, Peter A, Prof, Sinn, Bruno V, MD, Engels, Knut, MD, Mehta, Keyur, MBA, Nekljudova, Valentina, PhD, Untch, Michael, Prof

“…Summary Background Preclinical data suggest that triple-negative breast cancers are sensitive to interstrand crosslinking agents, and that synergy may exist…”
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Circulating microRNAs in plasma as early detection markers for breast cancer by Cuk, Katarina, Zucknick, Manuela, Heil, Jörg, Madhavan, Dharanija, Schott, Sarah, Turchinovich, Andrey, Arlt, Dorit, Rath, Michelle, Sohn, Christof, Benner, Axel, Junkermann, Hans, Schneeweiss, Andreas, Burwinkel, Barbara

“…In recent years, circulating miRNAs have attracted a great deal of attention as promising novel markers for various diseases. Here, we investigated their…”
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Nab-paclitaxel versus solvent-based paclitaxel in neoadjuvant chemotherapy for early breast cancer (GeparSepto—GBG 69): a randomised, phase 3 trial by Untch, Michael, Prof, Jackisch, Christian, Prof, Schneeweiss, Andreas, Prof, Conrad, Bettina, MD, Aktas, Bahriye, MD, Denkert, Carsten, Prof, Eidtmann, Holger, MD, Wiebringhaus, Hermann, MD, Kümmel, Sherko, MD, Hilfrich, Jörn, Prof, Warm, Mathias, Prof, Paepke, Stefan, MD, Just, Marianne, MD, Hanusch, Claus, MD, Hackmann, John, MD, Blohmer, Jens-Uwe, Prof, Clemens, Michael, Prof, Darb-Esfahani, Silvia, MD, Schmitt, Wolfgang Daniel, MD, Dan Costa, Serban, Prof, Gerber, Bernd, Prof, Engels, Knut, MD, Nekljudova, Valentina, PhD, Loibl, Sibylle, Prof, von Minckwitz, Gunter, Prof

“…Summary Background In metastatic breast cancer, nab-paclitaxel has been shown to significantly increase progression-free survival compared with solvent-based…”
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Response-Guided Neoadjuvant Chemotherapy for Breast Cancer by VON MINCKWITZ, Gunter, BLOHMER, Jens Uwe, JACKISCH, Christian, KAUFMANN, Manfred, KÜMMEL, Sherko, PAEPKE, Stefan, SCHNEEWEISS, Andreas, UNTCH, Michael, ZAHM, Dirk Michael, MEHTA, Keyur, LOIBL, Sibylle, DAN COSTA, Serban, DENKERT, Carsten, EIDTMANN, Holger, EIERMANN, Wolfgang, GERBER, Bernd, HANUSCH, Claus, HILFRICH, Jörn, HUOBER, Jens

“…We investigated disease-free survival (DFS) and overall survival (OS) after response-guided neoadjuvant chemotherapy in patients with early breast cancer. We…”
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Muscle strength in breast cancer patients receiving different treatment regimes by Klassen, Oliver, Schmidt, Martina E., Ulrich, Cornelia M., Schneeweiss, Andreas, Potthoff, Karin, Steindorf, Karen, Wiskemann, Joachim

“…Background Muscle dysfunction and sarcopenia have been associated with poor performance status, an increased mortality risk, and greater side effects in…”
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Phase III Study of Bevacizumab Plus Docetaxel Compared With Placebo Plus Docetaxel for the First-Line Treatment of Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer by MILES, David W, CHAN, Arlene, HARBECK, Nadia, STEGER, Guenther G, SCHNEEWEISS, Andreas, WARDLEY, Andrew M, CHLISTALLA, Andreas, ROMIEU, Gilles, DIRIX, Luc Y, CORTES, Javier, PIVOT, Xavier, TOMCZAK, Piotr, DELOZIER, Thierry, JOO HYUK SOHN, PROVENCHER, Louise, PUGLISI, Fabio

“…The efficacy and safety of combining bevacizumab (7.5 and 15 mg/kg) with docetaxel as first-line therapy for human epidermal growth factor receptor 2 (HER2)…”
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Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer by MADHAVAN, Dharanija, ZUCKNICK, Manuela, BENNER, Axel, RIETHDORF, Sabine, TRUMPP, Andreas, SOHN, Christof, PANTEL, Klaus, SCHNEEWEISS, Andreas, BURWINKEL, Barbara, WALLWIENER, Markus, CUK, Katarina, MODUGNO, Caroline, SCHARPFF, Martina, SCHOTT, Sarah, HEIL, Jörg, TURCHINOVICH, Andrey, RONGXI YANG

“…The use of circulating tumor cells (CTC) as a prognostic marker in metastatic breast cancer (MBC) has been well established. However, their efficacy and…”
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Randomized Phase II Study of the Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Cetuximab With Cisplatin Versus Cisplatin Alone in Patients With Metastatic Triple-Negative Breast Cancer by BASELGA, José, GOMEZ, Patricia, GOEMINNE, Jean-Charles, GRAAS, Marie-Pascale, KENNEDY, M. John, CIRUELOS GIL, Eva Maria, SCHNEEWEISS, Andreas, ZUBEL, Angela, GROOS, Jutta, MELEZINKOVA, Helena, AWADA, Ahmad, GREIL, Richard, BRAGA, Sofia, CLIMENT, Miguel A, WARDLEY, Andrew M, KAUFMAN, Bella, STEMMER, Salomon M, PEGO, António, CHAN, Arlene

“…Epidermal growth factor receptor is overexpressed in metastatic triple-negative breast cancers (mTNBCs), an aggressive subtype of breast cancer. Our randomized…”
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Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis by Madhavan, Dharanija, Wallwiener, Markus, Bents, Karin, Zucknick, Manuela, Nees, Juliane, Schott, Sarah, Cuk, Katarina, Riethdorf, Sabine, Trumpp, Andreas, Pantel, Klaus, Sohn, Christof, Schneeweiss, Andreas, Surowy, Harald, Burwinkel, Barbara

“…Circulating or cell-free DNA (cfDNA) has been evaluated as a biomarker in many cancers including breast cancer. In particular, integrity of cfDNA has been…”
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Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study by Hennigs, André, Riedel, Fabian, Gondos, Adam, Sinn, Peter, Schirmacher, Peter, Marmé, Frederik, Jäger, Dirk, Kauczor, Hans-Ulrich, Stieber, Anne, Lindel, Katja, Debus, Jürgen, Golatta, Michael, Schütz, Florian, Sohn, Christof, Heil, Jörg, Schneeweiss, Andreas

“…In Germany, most breast cancer patients are treated in specialized breast cancer units (BCU), which are certified, and routinely monitored. Herein, we evaluate…”
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Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis by Insua‐Rodríguez, Jacob, Pein, Maren, Hongu, Tsunaki, Meier, Jasmin, Descot, Arnaud, Lowy, Camille M, De Braekeleer, Etienne, Sinn, Hans‐Peter, Spaich, Saskia, Sütterlin, Marc, Schneeweiss, Andreas, Oskarsson, Thordur

“…Metastatic progression remains a major burden for cancer patients and is associated with eventual resistance to prevailing therapies such as chemotherapy…”
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Plasma microRNA panel for minimally invasive detection of breast cancer by Cuk, Katarina, Zucknick, Manuela, Madhavan, Dharanija, Schott, Sarah, Golatta, Michael, Heil, Jörg, Marmé, Frederik, Turchinovich, Andrey, Sinn, Peter, Sohn, Christof, Junkermann, Hans, Schneeweiss, Andreas, Burwinkel, Barbara

“…Over the last few years, circulating microRNAs (miRNAs) have emerged as promising novel and minimally invasive markers for various diseases, including cancer…”
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Metronomic cyclophosphamide treatment in metastasized breast cancer patients: immunological effects and clinical outcome by Ge, Yingzi, Domschke, Christoph, Stoiber, Natalija, Schott, Sarah, Heil, Joerg, Rom, Joachim, Blumenstein, Maria, Thum, Janina, Sohn, Christof, Schneeweiss, Andreas, Beckhove, Philipp, Schuetz, Florian

“…Severe immune suppression is frequent in late-stage tumor patients and promotes tumor immune evasion and subsequent tumor progression. Regulatory T cells…”
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