Search Results - "Andreas, Friedl"

Syndecan-1-Induced ECM Fiber Alignment Requires Integrin αvβ3 and Syndecan-1 Ectodomain and Heparan Sulfate Chains by Yang, Ning, Friedl, Andreas

“…Expression of the cell surface proteoglycan syndecan-1 (Sdc1) is frequently induced in stromal fibroblasts of invasive breast carcinomas. We have recently…”
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Syndecan-1 in Breast Cancer Stroma Fibroblasts Regulates Extracellular Matrix Fiber Organization and Carcinoma Cell Motility by Yang, Ning, Mosher, Rachel, Seo, Songwon, Beebe, David, Friedl, Andreas

“…Stromal fibroblasts of breast carcinomas frequently express the cell surface proteoglycan syndecan-1 (Sdc1). In human breast carcinoma samples, stromal Sdc1…”
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Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models by Sung, Kyung Eun, Su, Xiaojing, Berthier, Erwin, Pehlke, Carolyn, Friedl, Andreas, Beebe, David J

“…The utilization of 3D, physiologically relevant in vitro cancer models to investigate complex interactions between tumor and stroma has been increasing. Prior…”
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Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases by Chute, Colleen, Yang, Xinhai, Meyer, Kristy, Yang, Ning, O'Neil, Keelin, Kasza, Ildiko, Eliceiri, Kevin, Alexander, Caroline, Friedl, Andreas

“…Syndecan-1 (Sdc1), a cell surface heparan sulfate proteoglycan normally expressed primarily by epithelia and plasma cells, is aberrantly induced in stromal…”
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Glypican 1 Stimulates S Phase Entry and DNA Replication in Human Glioma Cells and Normal Astrocytes by Qiao, Dianhua, Meyer, Kristy, Friedl, Andreas

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Neutrophil gelatinase-associated lipocalin (NGAL) is a predictor of poor prognosis in human primary breast cancer by Bauer, Maret, Eickhoff, Jens C., Gould, Michael N., Mundhenke, Christoph, Maass, Nicolai, Friedl, Andreas

“…Neutrophil gelatinase-associated lipocalin (NGAL) is a small, secreted glycoprotein with proposed functions in cell proliferation, survival and morphogenesis…”
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Signal Transducers and Activators of Transcription Mediate Fibroblast Growth Factor―Induced Vascular Endothelial Morphogenesis by XINHAI YANG, DIANHUA QIAO, MEYER, Kristy, FRIEDL, Andreas

“…The fibroblast growth factors (FGF) play diverse roles in development, wound healing, and angiogenesis. The intracellular signal transduction pathways, which…”
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Insurance demand and social comparison: An experimental analysis by Friedl, Andreas, de Miranda, Katharina Lima, Schmidt, Ulrich

“…This paper analyzes whether social comparison can explain the low take-up of disaster insurance usually reported in field studies. We argue that risks in the…”
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Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices by Sung, Kyung Eun, Su, Gui, Pehlke, Carolyn, Trier, Steven M, Eliceiri, Kevin W, Keely, Patricia J, Friedl, Andreas, Beebe, David J

“…Abstract Interest in constructing a reliable 3-dimensional (3D) collagen culture platform in microfabricated systems is increasing as researchers strive to…”
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Shedding of Syndecan-1 by Stromal Fibroblasts Stimulates Human Breast Cancer Cell Proliferation via FGF2 Activation by Su, Gui, Blaine, Stacy A., Qiao, Dianhua, Friedl, Andreas

“…The cell surface heparan sulfate proteoglycan syndecan-1 is induced in stromal fibroblasts of breast carcinomas and participates in a reciprocal feedback loop,…”
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Functional screen of paracrine signals in breast carcinoma fibroblasts by Su, Gui, Sung, Kyung E, Beebe, David J, Friedl, Andreas

“…Stromal fibroblasts actively participate in normal mammary gland homeostasis and in breast carcinoma growth and progression by secreting paracrine factors;…”
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Membrane type 1 matrix metalloproteinase-mediated stromal syndecan-1 shedding stimulates breast carcinoma cell proliferation by Su, Gui, Blaine, Stacy A, Qiao, Dianhua, Friedl, Andreas

“…Mounting evidence implicates stromal fibroblasts in breast carcinoma progression. We have recently shown in three-dimensional coculture experiments that human…”
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HSulf-1 inhibits angiogenesis and tumorigenesis in vivo by NARITA, Keishi, STAUB, Julie, CHIEN, Jeremy, MEYER, Kristy, BAUER, Maret, FRIEDL, Andreas, RAMAKRISHNAN, Sundaram, SHRIDHAR, Viji

“…We previously identified HSulf-1 as a down-regulated gene in several tumor types including ovarian, breast, and hepatocellular carcinomas. Loss of HSulf-1,…”
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The transcription factor REST is lost in aggressive breast cancer by Wagoner, Matthew P, Gunsalus, Kearney T W, Schoenike, Barry, Richardson, Andrea L, Friedl, Andreas, Roopra, Avtar

“…The function of the tumor suppressor RE1 silencing transcription factor (REST) is lost in colon and small cell lung cancers and is known to induce…”
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Angiogenesis Induced by Signal Transducer and Activator of Transcription 5A (STAT5A) Is Dependent on Autocrine Activity of Proliferin by Yang, Xinhai, Qiao, Dianhua, Meyer, Kristy, Pier, Thomas, Keles, Sunduz, Friedl, Andreas

“…Multiple secreted factors induce the formation of new blood vessels (angiogenesis). The signal transduction events that orchestrate the numerous cellular…”
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Induction of syndecan-1 expression in stromal fibroblasts promotes proliferation of human breast cancer cells by MAEDA, Takashi, ALEXANDER, Caroline M, FRIEDL, Andreas

“…Infiltrating carcinomas characteristically elicit a reactive stromal response, and accumulating evidence indicates that tumor stroma fibroblasts reciprocally…”
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Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells by Qiao, Dianhua, Yang, Xinhai, Meyer, Kristy, Friedl, Andreas

“…Glypican-1 (GPC1), a member of the mammalian glypican family of heparan sulfate proteoglycans, is highly expressed in glioma blood vessel endothelial cells…”
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Syndecan-1 and syndecan-4 are overexpressed in an estrogen receptor-negative, highly proliferative breast carcinoma subtype by BABA, Füsun, SWARTZ, Kathryn, VAN BUREN, Regina, EICKHOFF, Jens, YONG ZHANG, WOLBERG, William, FRIEDL, Andreas

“…Members of the syndecan and glypican families of cell surface heparan sulfate proteoglycans (HSPGs) are modulators of growth factor signaling and cell…”
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Phase I Trial of a Monoclonal Antibody Specific for αvβ3 Integrin (MEDI-522) in Patients with Advanced Malignancies, Including an Assessment of Effect on Tumor Perfusion by MCNEEL, Douglas G, EICKHOFF, Jens, JIANLIANG ZHANG, HAMMERSHAIMB, Luz, ZWIEBEL, James A, WILDING, George, LEE, Fred T, KING, David M, ALBERTI, Dona, THOMAS, James P, FRIEDL, Andreas, KOLESAR, Jill, MARNOCHA, Rebecca, VOLKMAN, Jennifer

“…At present, a variety of agents targeting tumor angiogenesis are under clinical investigation as new therapies for patients with cancer. Overexpression of the…”
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Phase I Pharmacokinetic and Pharmacodynamic Study of Recombinant Human Endostatin in Patients With Advanced Solid Tumors by THOMAS, James P, ARZOOMANIAN, Rhoda Z, FOGLER, William, SCHILLER, Joan H, WILDING, George, ALBERTI, Dona, MARNOCHA, Rebecca, LEE, Fred, FRIEDL, Andreas, TUTSCH, Kendra, DRESEN, Amy, GEIGER, Peter, PLUDA, James

“…Endostatin is the first endogenous angiogenesis inhibitor to enter clinical trials. Laboratory investigations with endostatin have indicated broad antitumor…”
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