Search Results - "André, B."

Targeting replication stress in cancer therapy by da Costa, Alexandre André B. A., Chowdhury, Dipanjan, Shapiro, Geoffrey I., D’Andrea, Alan D., Konstantinopoulos, Panagiotis A.

“…Replication stress is a major cause of genomic instability and a crucial vulnerability of cancer cells. This vulnerability can be therapeutically targeted by…”
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Asymmetric Synthesis of Fluoro, Fluoromethyl, Difluoromethyl, and Trifluoromethylcyclopropanes by Pons, Amandine, Delion, Laetitia, Poisson, Thomas, Charette, André B, Jubault, Philippe

“…Conspectus Fluorine-containing cyclopropanes are a subclass of cyclopropane derivatives that have generated considerable interest in medicinal chemistry for…”
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Diastereoselective Borocyclopropanation of Allylic Ethers Using a Boromethylzinc Carbenoid by Benoit, Guillaume, Charette, André B

“…A borocyclopropanation of (E)- and (Z)-allylic ethers and styrene derivatives via the Simmons–Smith reaction using a novel boromethylzinc carbenoid is…”
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Recent Progress Toward the Synthesis of Trifluoromethyl‐ and Difluoromethyl‐Substituted Cyclopropanes by Bos, Maxence, Poisson, Thomas, Pannecoucke, Xavier, Charette, André B., Jubault, Philippe

“…This Minireview describes recent advances toward the synthesis of trifluoromethyl‐ and difluoromethyl‐substituted cyclopropanes. Synthetic methodologies using…”
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Synthesis of Fluoro‐, Monofluoromethyl‐, Difluoromethyl‐, and Trifluoromethyl‐Substituted Three‐Membered Rings by Decaens, Jonathan, Couve‐Bonnaire, Samuel, Charette, André B., Poisson, Thomas, Jubault, Philippe

“…This Minireview describes recent advances toward the synthesis of fluoro‐, monofluoromethyl‐, difluoromethyl‐, and trifluoromethyl‐substituted three‐membered…”
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Developments in the treatment of Fabry disease by Veen, Sanne J., Hollak, Carla E. M., Kuilenburg, André B. P., Langeveld, Mirjam

“…Enzyme replacement therapy (ERT) with recombinant α‐galactosidase A (r‐αGAL A) for the treatment of Fabry disease has been available for over 15 years…”
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The influence of peri-implant keratinized mucosa on brushing discomfort and peri-implant tissue health by Souza, André B., Tormena, Mariana, Matarazzo, Flávia, Araújo, Maurício G.

“…Objective The aim of this study was to compare the level of brushing discomfort (BD) during oral hygiene and peri‐implant clinical variables between patients…”
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Lessons Learned from HERA: the First Alport Syndrome Therapeutic Clinical Trial by Weinstock, B André

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Potassium tert-Butoxide Promoted Intramolecular Arylation via a Radical Pathway by Roman, Daniela Sustac, Takahashi, Yoko, Charette, André B

“…Potassium tert-butoxide mediated intramolecular cyclization of aryl ethers, amines, and amides was efficiently performed under microwave irradiation to provide…”
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Controlled and Chemoselective Reduction of Secondary Amides by Pelletier, Guillaume, Bechara, William S, Charette, André B

“…This communication describes a metal-free methodology involving an efficient and controlled reduction of secondary amides to imines, aldehydes, and amines in…”
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The role of land‐use history in driving successional pathways and its implications for the restoration of tropical forests by Jakovac, Catarina C., Junqueira, André B., Crouzeilles, Renato, Peña‐Claros, Marielos, Mesquita, Rita C. G., Bongers, Frans

“…ABSTRACT Secondary forests are increasingly important components of human‐modified landscapes in the tropics. Successional pathways, however, can vary…”
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Influence of the keratinized mucosa on the stability of peri‐implant tissues and brushing discomfort: A 4‐year follow‐up study by Perussolo, Jeniffer, Souza, André B., Matarazzo, Flávia, Oliveira, Ricardo P., Araújo, Mauricio G.

“…Objective The purpose of the present prospective follow‐up study was to evaluate the long‐term influence of the peri‐implant keratinized mucosa (KM) on…”
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Triflic Anhydride Mediated Synthesis of Imidazo[1,5‑a]azines by Pelletier, Guillaume, Charette, André B

“…Imidazo[1,5-a]azines are synthesized in moderate to excellent yields using a mild cyclodehydration/aromatization reaction triggered by the use of triflic…”
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C–H Functionalization of Cyclopropanes: A Practical Approach Employing a Picolinamide Auxiliary by Roman, Daniela Sustac, Charette, André B

“…A Pd-catalyzed, picolinamide-enabled, and efficient C–H arylation of cyclopropanes is described. The reaction can be promoted by either a silver additive or…”
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Effects of climate change and anthropogenic pressures in the water quality of a coastal lagoon (Ria Formosa, Portugal) by Rodrigues, Marta, Rosa, Alexandra, Cravo, Alexandra, Jacob, José, Fortunato, André B.

“…Understanding how climatic and anthropogenic drivers will influence coastal lagoons is fundamental to guarantee their preservation and sustainability. The Ria…”
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Physical activity and exercise on diabetic foot related outcomes: A systematic review by Matos, Monica, Mendes, Romeu, Silva, André B., Sousa, Nelson

“…Diabetic foot is one of the most common complications of diabetes. It has the potential risk of pathologic consequences including infection, ulceration and…”
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Retrospective study of long-term outcomes of enzyme replacement therapy in Fabry disease: Analysis of prognostic factors by Arends, Maarten, Biegstraaten, Marieke, Hughes, Derralynn A, Mehta, Atul, Elliott, Perry M, Oder, Daniel, Watkinson, Oliver T, Vaz, Frédéric M, van Kuilenburg, André B P, Wanner, Christoph, Hollak, Carla E M

“…Despite enzyme replacement therapy, disease progression is observed in patients with Fabry disease. Identification of factors that predict disease progression…”
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Asymmetric Synthesis of (−)-Cannabidiol (CBD), (−)‑Δ9‑Tetrahydrocannabinol (Δ9‑THC) and Their cis Analogs Using an Enantioselective Organocatalyzed Diels–Alder Reaction by Pauvert, Yann, Charette, André B.

“…Herein we describe an asymmetric synthesis of the pharmacologically relevant natural (−)-trans-CBD and psychoactive (−)-trans-Δ9-THC, as well as their…”
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Instability and Spontaneous Reconstruction of Few-Monolayer Thick GaN Graphitic Structures by Kolobov, A. V, Fons, P, Tominaga, J, Hyot, B, André, B

“…Two-dimensional (2D) semiconductors are a very hot topic in solid state science and technology. In addition to van der Waals solids that can be easily formed…”
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Difluorocarbene Addition to Alkenes and Alkynes in Continuous Flow by Rullière, Pauline, Cyr, Patrick, Charette, André B

“…The first in-flow difluorocarbene generation and addition to alkenes and alkynes is reported. The application of continuous flow technology allowed for the…”
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