Search Results - "Andre, Eunice"
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Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction
Published in Anesthesiology (Philadelphia) (01-06-2010)“…Volatile anesthetics such as isoflurane and halothane have been in clinical use for many years and represent the group of drugs most commonly used to maintain…”
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2
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs
Published in Journal of applied physiology (1985) (01-08-2006)“…1 Center of Excellence for the Study of Inflammation, University of Ferrara, Ferrara; 2 Department of Critical Care Medicine and Surgery, University of…”
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4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
Published in Proceedings of the National Academy of Sciences - PNAS (14-08-2007)“…TRPA1 is an excitatory ion channel expressed by a subpopulation of primary afferent somatosensory neurons that contain substance P and calcitonin gene-related…”
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4
Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-2008)“…Prostaglandins (PG) are known to induce pain perception indirectly by sensitizing nociceptors. Accordingly, the analgesic action of nonsteroidal…”
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5
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system
Published in Brain (London, England : 1878) (01-02-2012)“…The California bay laurel or Umbellularia californica (Hook. & Arn.) Nutt., is known as the 'headache tree' because the inhalation of its vapours can cause…”
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Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents
Published in The Journal of clinical investigation (01-07-2008)“…Cigarette smoke (CS) inhalation causes an early inflammatory response in rodent airways by stimulating capsaicin-sensitive sensory neurons that express…”
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7
Role of TRPA1 in the pharmacological effect triggered by the topical application of trans-anethole in mice
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2024)“…Purpose : This study investigated the pharmacological effects of topical trans-anethole, a natural compound found in anise, star anise, and fennel essential…”
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Topical Application of Cinnamaldehyde Promotes Faster Healing of Skin Wounds Infected with Pseudomonas aeruginosa
Published in Molecules (Basel, Switzerland) (25-04-2019)“…Wound healing can be delayed following colonization and infection with the common bacterium . While multiple therapies are used for their treatment, these are…”
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miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4
Published in Journal of investigative dermatology (01-01-2023)“…Growing evidence indicates that transient receptor potential (TRP) channels contribute to different forms of pruritus. However, the endogenous mediators that…”
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10
Role of nitric oxide, bradykinin B 2 receptor, and TRPV1 in the airway alterations caused by simvastatin in rats
Published in European journal of pharmacology (05-12-2021)“…Dry cough has been reported in patients receiving statin therapy. However, the underlying mechanism or other possible alterations in the airways induced by…”
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The role of TRPA1 and TRPV4 channels in bronchoconstriction and plasma extravasation in airways of rats treated with captopril
Published in Pulmonary pharmacology & therapeutics (01-12-2020)“…Angiotensin-converting enzyme inhibitors (ACEis) may cause adverse airway events, such as cough and angioedema, due to a reduction in bradykinin breakdown and…”
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12
Anti-proliferative and anti-inflammatory effects of the application of baclofen cream, a GABAB receptor agonist, on skin inflammation in mice
Published in European journal of pharmacology (15-09-2023)“…Previous studies have demonstrated the role of γ-aminobutyric acid type B (GABAB) receptors in skin-related conditions and pain. However, most studies have…”
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The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain
Published in European journal of pharmacology (15-01-2015)“…Sympathetic fibres maintain some forms of neuropathic pain, but the underlying mechanisms are poorly understood. Therefore, this study investigated the…”
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Repeated doses of captopril induce airway hyperresponsiveness by modulating the TRPV1 receptor in rats
Published in Pulmonary pharmacology & therapeutics (01-09-2024)“…Although TRPV1 receptors play an essential role in the adverse effects on the airways following captopril treatment, there is no available evidence of their…”
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Neuronal and non-neuronal transient receptor potential ankyrin 1 mediates UVB radiation-induced skin inflammation in mice
Published in Life sciences (1973) (01-12-2020)“…Neuronal and non-neuronal TRPA1 channel plays an active role in the pathogenesis of several skin inflammatory diseases. Although a recent study identified the…”
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Role of TRPA1 receptors in skin inflammation induced by volatile chemical irritants in mice
Published in European journal of pharmacology (05-09-2019)“…Contact dermatitis is a very common inflammatory reaction in the skin, causing not only aesthetic problems but also loss functionality at work. The molecular…”
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17
Oxidative and nitrosative stresses in cerebral malaria: can we target them to avoid a bad prognosis?
Published in Journal of antimicrobial chemotherapy (01-06-2020)“…There is currently a global effort to reduce malaria morbidity and mortality. However, malaria still results in the deaths of thousands of people every year…”
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Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents
Published in The FASEB journal (01-12-2010)“…Acetaminophen [N-acetyl-p-aminophenol (APAP)] is the most common antipyretic/analgesic medicine worldwide. If APAP is overdosed, its metabolite,…”
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Dopamine D 1 and D 2 receptors mediate neuropeptide S-induced antinociception in the mouse formalin test
Published in European journal of pharmacology (15-09-2019)“…Neuropeptide S (NPS) is the endogenous ligand of a G-protein coupled receptor named NPS receptor. The NPS system controls several biological functions,…”
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The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant‐ and anxiolytic‐like actions in mice
Published in British journal of pharmacology (01-09-2014)“…Background and Purpose Transient receptor potential vanilloid 1 (TRPV1) and TRP ankyrin 1 (TRPA1) are involved in many biological processes, including…”
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