Search Results - "Andre, E."

Nano-Enabled COVID-19 Vaccines: Meeting the Challenges of Durable Antibody Plus Cellular Immunity and Immune Escape by Nel, André E, Miller, Jeff F

“…At the time of preparing this Perspective, large-scale vaccination for COVID-19 is in progress, aiming to bring the pandemic under control through…”
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Assessing and Mitigating the Hazard Potential of Two-Dimensional Materials by Guiney, Linda M, Wang, Xiang, Xia, Tian, Nel, André E, Hersam, Mark C

“…The family of two-dimensional (2D) materials is comprised of a continually expanding palette of unique compositions and properties with potential applications…”
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Multifunctional Lipid Bilayer Nanocarriers for Cancer Immunotherapy in Heterogeneous Tumor Microenvironments, Combining Immunogenic Cell Death Stimuli with Immune Modulatory Drugs by Nel, André E, Mei, Kuo-Ching, Liao, Yu-Pei, Liu, Xiangsheng

“…In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a critical role in determining tumor expansion, antitumor immunity,…”
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Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water by Brown, André E.X, Litvinov, Rustem I, Discher, Dennis E, Purohit, Prashant K, Weisel, John W

“…Blood clots and thrombi consist primarily of a mesh of branched fibers made of the protein fibrin. We propose a molecular basis for the marked extensibility…”
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Use of nano engineered approaches to overcome the stromal barrier in pancreatic cancer by Meng, Huan, Nel, Andre E.

“…While chemotherapy is the only approved non-surgical option for the majority of pancreatic cancer patients, it rarely results in a cure. The failure to respond…”
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Zebrafish: An In Vivo Model for Nano EHS Studies by Lin, Sijie, Zhao, Yan, Nel, André E., Lin, Shuo

“…To assure a responsible and sustainable growth of nanotechnology, the environmental health and safety (EHS) aspect of engineered nanomaterials and nano‐related…”
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The genome of the recently domesticated crop plant sugar beet (Beta vulgaris) by Dohm, Juliane C., Minoche, André E., Holtgräwe, Daniela, Capella-Gutiérrez, Salvador, Zakrzewski, Falk, Tafer, Hakim, Rupp, Oliver, Sörensen, Thomas Rosleff, Stracke, Ralf, Reinhardt, Richard, Goesmann, Alexander, Kraft, Thomas, Schulz, Britta, Stadler, Peter F., Schmidt, Thomas, Gabaldón, Toni, Lehrach, Hans, Weisshaar, Bernd, Himmelbauer, Heinz

“…A full genome sequence is presented of sugar beet Beta vulgaris , the first plant belonging to Caryophyllales to have its genome sequenced; spinach was…”
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Management strategy evaluation: best practices by Punt, André E, Butterworth, Doug S, de Moor, Carryn L, De Oliveira, José A A, Haddon, Malcolm

“…Management strategy evaluation (MSE) involves using simulation to compare the relative effectiveness for achieving management objectives of different…”
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Evaluating methods for setting catch limits in data-limited fisheries by Carruthers, Thomas R., Punt, André E., Walters, Carl J., MacCall, Alec, McAllister, Murdoch K., Dick, Edward J., Cope, Jason

“…•We undertake an MSE of data-limited methods for setting catch limits.•Methods that dynamically account for current abundance or depletion performed…”
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The Genetic Heterogeneity among Different Mouse Strains Impacts the Lung Injury Potential of Multiwalled Carbon Nanotubes by Wang, Xiang, Liao, Yu‐Pei, Telesca, Donatello, Chang, Chong Hyun, Xia, Tian, Nel, André E.

“…Genetic variation constitutes an important variable impacting the susceptibility to inhalable toxic substances and air pollutants, as reflected by…”
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The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles by Li, Ning, Xia, Tian, Nel, Andre E.

“…Ambient particulate matter (PM) is an environmental factor that has been associated with increased respiratory morbidity and mortality. The major effect of…”
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Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression by Lu, Jianqin, Liu, Xiangsheng, Liao, Yu-Pei, Salazar, Felix, Sun, Bingbing, Jiang, Wen, Chang, Chong Hyun, Jiang, Jinhong, Wang, Xiang, Wu, Anna M., Meng, Huan, Nel, Andre E.

“…While chemotherapy delivery by nanocarriers has modestly improved the survival prospects of pancreatic ductal adenocarcinoma (PDAC), additional engagement of…”
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The breeding strategy of female jumbo squid Dosidicus gigas: energy acquisition and allocation by Chen, Xinjun, Han, Fei, Zhu, Kai, Punt, André E., Lin, Dongming

“…Reproductive investment generally involves a trade-off between somatic growth and energy allocation for reproduction. Previous studies have inferred that jumbo…”
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Custom-Designed Nanomaterial Libraries for Testing Metal Oxide Toxicity by Pokhrel, Suman, Nel, André E, Mädler, Lutz

“…Advances in aerosol technology over the past 10 years have enabled the generation and design of ultrafine nanoscale materials for many applications. A key new…”
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Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO‑1 Pathway by Lu, Jianqin, Liu, Xiangsheng, Liao, Yu-Pei, Wang, Xiang, Ahmed, Ayman, Jiang, Wen, Ji, Ying, Meng, Huan, Nel, Andre E

“…Immunotherapy provides the best approach to reduce the high mortality of metastatic breast cancer (BC). We demonstrate a chemo-immunotherapy approach, which…”
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Classification NanoSAR Development for Cytotoxicity of Metal Oxide Nanoparticles by Liu, Rong, Rallo, Robert, George, Saji, Ji, Zhaoxia, Nair, Sumitra, Nel, André E., Cohen, Yoram

“…A classification‐based cytotoxicity nanostructure–activity relationship (nanoSAR) is presented based on a set of nine metal oxide nanoparticles to which…”
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Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress by Araujo, Jesus A, Nel, Andre E

“…Air Pollution has been associated with significant adverse health effects leading to increased morbidity and mortality. Cumulative epidemiological and…”
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Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice by Meng, Huan, Wang, Meiying, Liu, Huiyu, Liu, Xiangsheng, Situ, Allen, Wu, Bobby, Ji, Zhaoxia, Chang, Chong Hyun, Nel, Andre E

“…Recently, a commercial albumin-bound paclitaxel (PTX) nanocarrier (Abraxane) was approved as the first new drug for pancreatic ductal adenocarcinoma in almost…”
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Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line by Meng, Huan, Liong, Monty, Xia, Tian, Li, Zongxi, Ji, Zhaoxia, Zink, Jeffrey I, Nel, Andre E

“…Overexpression of drug efflux transporters such as P-glycoprotein (Pgp) protein is one of the major mechanisms for multiple drug resistance (MDR) in cancer…”
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Inorganic and Bioinorganic Solvent Exchange Mechanisms by Helm, Lothar, Merbach, André E

“…The simplest reaction on a metal ion in aqueous or nonaqueous solution is the exchange of a solvent molecule between the first and second coordination shells…”
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