Search Results - "Andrade de Mello, Ramon"
-
1
The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer
Published in PloS one (06-09-2013)“…Polymorphic variants in the 5p15, 6p12, 6p21, and 15q25 loci were demonstrated to potentially contribute to lung cancer carcinogenesis. Therefore, this study…”
Get full text
Journal Article -
2
PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: updated survival data
Published in Immunotherapy (01-05-2017)“…The treatment of non-small-cell lung cancer has changed after the development of the immune checkpoint inhibitors. Although the most studied biomarker is PD-L1…”
Get full text
Journal Article -
3
The role of PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: a network meta-analysis
Published in Immunotherapy (01-04-2016)“…Tumor programmed death ligand one (PD-L1) expression has been studied in several trials in non-small-cell lung cancer. We assessed the potential role of PD-L1…”
Get full text
Journal Article -
4
Current and future trends in neoadjuvant immunotherapy for the treatment of triple-negative breast cancer
Published in Immunotherapy (01-03-2024)“…Triple-negative breast cancer (TNBC) comprises 15-20% of all breast cancers (BC). Lacking targeted therapy options, TNBC becomes the focal point of clinical…”
Get more information
Journal Article -
5
Potential role of immunotherapy in advanced non-small-cell lung cancer
Published in OncoTargets and therapy (01-01-2017)“…Immuno checkpoint inhibitors have ushered in a new era with respect to the treatment of advanced non-small-cell lung cancer. Many patients are not suitable for…”
Get full text
Journal Article -
6
Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a retrospective study in a single comprehensive European cancer institution
Published in PloS one (06-02-2014)“…The use of cetuximab in combination with platinum (P) plus 5-fluorouracil (F) has previously been demonstrated to be effective in the treatment of metastatic…”
Get full text
Journal Article -
7
Insights into angiogenesis in non-small cell lung cancer: molecular mechanisms, polymorphic genes, and targeted therapies
Published in Recent patents on anti-cancer drug discovery (01-01-2012)“…Lung cancer is a highly prevalent disease worldwide. Currently, there are more than 150 million patients with lung cancer in the world, with more than 1…”
Get more information
Journal Article -
8
Targeting HER family in HER2-positive metastatic breast cancer: potential biomarkers and novel targeted therapies
Published in Pharmacogenomics (01-03-2015)“…HER2-targeted therapies have radically changed the prognosis of HER2-positive breast cancer over the last few years. However, resistance to these therapies has…”
Get full text
Journal Article -
9
Are there, or shall we discover, biomarkers to guide PD-1 inhibition?
Published in Immunotherapy (01-06-2016)“…Despite the recent success of PD-1/PD-L1-directed immunotherapy in a number of different malignancies, there are currently no effective biomarkers available to…”
Get full text
Journal Article -
10
Treatment Sequencing Strategies in Lung Cancer
Published in Zhongguo fei ai za zhi (20-05-2022)“…The advances in the lung cancer screening methods and therapeutics, together with awareness towards deleterious habits, such as smoking, is increasing the…”
Get full text
Journal Article -
11
Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies
Published in World journal of clinical oncology (10-11-2011)“…Lung cancer is currently the leading cause of cancer death in Western nations. Non-small cell lung cancer (NSCLC) represents 80% of all lung cancers, and…”
Get full text
Journal Article -
12
Current advances in targeted therapies for metastatic gastric cancer: improving patient care
Published in Future Oncology (01-03-2016)“…In this article, we review the literature on the current advances in targeted therapies for metastatic gastric cancer aimed at improving patient care. We…”
Get full text
Journal Article Book Review -
13
Renal failure due to primary amyloidosis: a case report and literature review
Published in São Paulo medical journal (01-05-2011)“…Primary amyloidosis, also known as AL amyloidosis, is commonly caused by clonal expansion of plasma cells in the bone marrow, thereby segregating light chains…”
Get full text
Journal Article -
14
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer
Published in The Journal of clinical investigation (01-01-2019)“…Replicative immortality is a hallmark of cancer cells governed by telomere maintenance. Approximately 90% of human cancers maintain their telomeres by…”
Get full text
Journal Article -
15
CRISPR-based strategies in infectious disease diagnosis and therapy
Published in Infection (01-06-2021)“…Purpose CRISPR gene-editing technology has the potential to transform the diagnosis and treatment of infectious diseases, but most clinicians are unaware of…”
Get full text
Journal Article -
16
Back to EGF+61 genetic polymorphisms and lung cancer risk: looking to the future
Published in São Paulo medical journal (01-01-2012)Get full text
Journal Article -
17
Loci identified through genome-wide association studies and lung cancer risk: is there anything more?
Published in São Paulo medical journal (01-01-2013)Get full text
Journal Article -
18
Update in Immunotherapy for Advanced Non-Small Cell Lung Cancer: Optimizing Treatment Sequencing and Identifying the Best Choices
Published in Cancers (01-09-2023)“…The introduction of immunotherapy has brought about a paradigm shift in the management of advanced non-small cell lung cancer (NSCLC). It has not only…”
Get full text
Journal Article -
19
Summary of international recommendations in 23 languages for patients with cancer during the COVID-19 pandemic
Published in The lancet oncology (01-06-2020)“…[...]we have translated the summary of the comprehensive recommendations into 22 languages (Arabic, Bulgarian, Catalan, Chinese, Croatian, Czech, Dutch,…”
Get full text
Journal Article -
20
The impact of telemedicine on cancer care: real-world experience from a Peruvian institute during the COVID-19 pandemic
Published in Future oncology (London, England) (01-10-2022)“…The COVID-19 pandemic caused discontinuities in cancer care (CC) in most countries. Here, the authors describe the real-world impacts of implementing a…”
Get full text
Journal Article