Search Results - "Andrade, Z A"

Schistosomiasis and liver fibrosis by ANDRADE, Z.A

“…Schistosoma mansoni infection invariably results in liver fibrosis of the host. This fibrosis may be represented by small focal areas of chronic inflammation…”
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Synthesis and thermal study of the prodrug of oxamniquine by ALMEIDA, A. E, FERREIRA, A. G, CRESPI, M. S, ANDRADE, Z. A, CHUNG, M.-C

“…Oxamniquine polymeric prodrug with potential antischistosomal activity was prepared using dextran T-70 as a carrier, which was analysed by HNMR, C NMR and IR…”
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Biomphalaria tenagophila / Schistosoma mansoni Interaction: Premises for a New Approach to Biological Control of Schistosomiasis by Coelho, P M Z, Carvalho, O S, Andrade, Z A, Martins-Sousa, R L, Rosa, F M, Barbosa, L, Pereira, C A J, Caldeira, R L, Jannotti-Passos, L K, Godard, A L B, Moreira, L A, Oliveira, G C, Franco, G R, Teles, H M S, Negrão-Corrêa, D

“…Biomphalaria tenagophila is very important for schistosomiasis transmission in Brazil. However its mechanisms of interaction with Schistosoma mansoni are still…”
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Decreased humoral and pathologic responses in undernourished mice infected with Schistosoma mansoni by OLIVEIRA, S. A, SILVA, L. M, BARBOSA, A. A, RIBEIRO-DOS-SANTOS, R, COUTINHO, E. M, ANDRADE, Z. A, SOARES, M. B. P

“…We previously demonstrated that mice subjected to a hypoproteinic diet showed milder chronic lesions on infection with Schistosoma mansoni than normally fed…”
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Expression of metalloproteinases (MMP-1, MMP-2, and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in schistosomal portal fibrosis by Gomez, D E, De Lorenzo, M S, Alonso, D F, Andrade, Z A

“…Focal extracellular matrix degradation morphologically identified in human portal pipestem fibrosis due to Schistosoma mansoni did not express…”
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Interstitial dendritic cells of the heart harbor Trypanosoma cruzi antigens in experimentally infected dogs: importance for the pathogenesis of chagasic myocarditis by Andrade, S G, Pimentel, A R, de Souza, M M, Andrade, Z A

“…Heart sections from 16 mongrel dogs, two normal controls and 14 infected with Trypanosoma cruzi, were submitted to immunohistochemical staining with either…”
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Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts by Medrado, Alena R.A.P., Pugliese, Lívia S., Reis, Sílvia Regina A., Andrade, Zilton A.

“…Background and Objective In re‐evaluating the effects of laser therapy in wound healing, the role of extracellular matrix elements and myofibroblasts, was…”
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The indeterminate phase of Chagas' disease: ultrastructural characterization of cardiac changes in the canine model by Andrade, Z A, Andrade, S G, Sadigursky, M, Wenthold, Jr, R J, Hilbert, S L, Ferrans, V J

“…The indeterminate phase of Chagas' disease is defined as the prolonged period of clinically silent infection that follows the phase of acute primary infection…”
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The Study of T‐Cell Activation in Peripheral Blood and Spleen of Hepatosplenic Patients Suggests an Exchange of Cells Between these Two Compartments in Advanced Human Schistosomiasis Mansoni Infection by TEIXEIRA‐CARVALHO, A., MARTINS‐FILHO, O. A., ANDRADE, Z. A., CUNHA‐MELLO, J. R., WILSON, R. A., CORRÊA‐OLIVEIRA, R.

“…A histopathological and immunophenotypic study was performed on the spleen of patients with hepatosplenic (HS) schistosomiasis mansoni. Morphological data…”
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Myocardial changes in acute Trypanosoma cruzi infection. Ultrastructural evidence of immune damage and the role of microangiopathy by Andrade, ZA, Andrade, SG, Correa, R, Sadigursky, M, Ferrans, VJ

“…Histological and ultrastructural studies of the hearts of dogs sacrificed 18 to 26 days after intraperitoneal inoculation with 4 x 10(5) blood forms of the 12…”
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Morphology of chronic collagen resorption. A study on the late stages of schistosomal granuloma involution by Andrade, ZA, Grimaud, JA

“…Hepatic periovular schistosomal granulomas produced in mice with 50 cercariae per 10 weeks of infection were seen to involute following curative treatment of…”
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Characterization of the murine model of schistosomal hepatic periportal fibrosis ('pipestem' fibrosis) by ANDRADE, Z. A, CHEEVER, A. W

“…During mild (one to two pairs of worms) and prolonged (23 weeks or more) mouse infections with Schistosoma mansoni, but not with S. japonicum, periovular…”
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Extracellular matrix degradation in parasitic diseases by Andrade, Z A

“…1. Fibrosis is an important manifestation of several parasitic diseases, but is not irreversible. A marked degree of extracellular matrix degradation can occur…”
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Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy by Andrade, ZA, Grimaud, JA

“…Mice with 64-day-old Schistosoma mansoni infection (+/- 27 worms, 8-12 pairs) were treated simultaneously with oxamniquine and hycanthone. The cure rate was…”
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Pathogenesis of schistosomal 'pipestem' fibrosis: a low-protein diet inhibits the development of 'pipestem' fibrosis in mice by COUTINHO, E. M., DE SOUZA, M. M., SILVA, L. M., CAVALCANTI, C. L., DE ARAUJO, R. E., BARBOSA Jr, A. A., CHEEVER, A. W., ANDRADE, Z. A.

“…Mice maintained on a low protein diet for 30 days and then infected with Schistosoma mansoni for 16 weeks completely failed to develop ‘pipestem fibrosis’ of…”
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Hepatic connective tissue changes in hepatosplenic schistosomiasis by Andrade, Z A, Peixoto, E, Guerret, S, Grimaud, J A

“…Destruction of intrahepatic portal vein branches with dispersion of smooth muscle cells into the periportal fibrosis and preservation of arterial and ductal…”
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Hepatic capillariasis in rats: a new model for testing antifibrotic drugs by de Souza, M M, Silva, L M, Barbosa, Jr, A A, de Oliveira, I R, Paraná, R, Andrade, Z A

“…Rats infected with the helminth Capillaria hepatica regularly develop septal hepatic fibrosis that may progress to cirrhosis in a relatively short time…”
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Localization of eosinophil major basic protein onto eggs of Schistosoma mansoni in human pathologic tissue by Kephart, GM, Andrade, ZA, Gleich, GJ

“…The eosinophil granule major basic protein (MBP), constituting the core of the granule, is toxic to helminths and mammalian cells in vitro. To determine…”
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Reversal of advanced liver fibrosis in rabbits with Schistosomiasis japonica by Dunn, M A, Cheever, A W, Paglia, L M, Kelly, E P, Duvall, R H, Andrade, Z A, Goldner, F H

“…Advanced liver fibrosis is generally considered to be irreversible. We studied the reversibility of marked liver fibrosis in rabbits infected with Schistosoma…”
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Enhancement of chronic Trypanosoma cruzi myocarditis in dogs treated with low doses of cyclophosphamide by Andrade, ZA, Andrade, SG, Sadigursky, M

“…An enhancement of chronic myocarditis was obtained in dogs chronically infected with Trypanosoma cruzi protozoa soon after they were submitted to treatment…”
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