Chronic Pulmonary Microaspiration: High-resolution Computed Tomographic Findings in 13 Patients

PURPOSE:The aim of the study was to describe the high-resolution computed tomography (CT) manifestations of chronic pulmonary microaspiration, a condition characterized by recurrent subclinical aspiration of small droplets of gastric contents or foreign particles into the lungs. MATERIALS AND METHOD...

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Bibliographic Details
Published in:	Journal of thoracic imaging Vol. 29; no. 5; pp. 298 - 303
Main Authors:	Pereira-Silva, Jorge L, Silva, Cleonice Isabela S, Araújo Neto, Cesar A, Andrade, Thamine L, Müller, Nestor L
Format:	Journal Article
Language:	English
Published:	United States by Lippincott Williams & Wilkins 01-09-2014
Subjects:	Aged Aged, 80 and over Chronic Disease Female Humans Lung - diagnostic imaging Male Middle Aged Pneumonia, Aspiration - diagnostic imaging Retrospective Studies Tomography, X-Ray Computed - methods
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Summary:	PURPOSE:The aim of the study was to describe the high-resolution computed tomography (CT) manifestations of chronic pulmonary microaspiration, a condition characterized by recurrent subclinical aspiration of small droplets of gastric contents or foreign particles into the lungs. MATERIALS AND METHODS:We reviewed the CT findings in 13 consecutive patients with clinical (n=13) and histologic (n=1) diagnosis of chronic pulmonary microaspiration. Twelve patients presented with persistent cough, but none had a clinical history of acute aspiration. One patient was asymptomatic. All patients had volumetric CT of the chest reconstructed using thin sections (1 to 1.3 mm) at the time of diagnosis. The CT scans were interpreted by 3 chest radiologists who reached a final decision by consensus. RESULTS:All 13 patients had centrilobular nodules and ground-glass opacities that involved mainly the dependent lung regions in 11 patients and had a random distribution in 2. Other common findings included branching opacities (n=10), small foci of consolidation (n=7), septal lines (n=5), and bronchiectasis (n=7). The 13 patients had at least 1 risk factor for aspiration including gastroesophageal reflux (n=9), hiatus hernia (n=6), esophageal dysfunction (n=3), oropharyngeal dysphagia (n=1), esophageal carcinoma (n=1), and use of sedatives (n=2). CONCLUSIONS:The high-resolution CT manifestations of chronic pulmonary microaspiration consist mainly of centrilobular nodules and ground-glass opacities that tend to involve predominately the dependent regions. Branching opacities and small foci of consolidation are seen in the majority of cases.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0883-5993 1536-0237
DOI:	10.1097/RTI.0000000000000091