Search Results - "Andrade, Sonia A."
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Analysis of LruC lipoprotein and identification of peptides candidates for vaccine development and diagnosis of leptospirosis
Published in PloS one (06-02-2023)“…Leptospirosis is a public health concern with lethality around 15% of the total cases. The current vaccines against Leptospira infection based on bacterins…”
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Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors
Published in The journal of venomous animals and toxins including tropical diseases (2021)“…In Central and South America, snakebite envenomation is mainly caused by spp. snakes, whose venoms feature significant biochemical richness, including serine…”
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Antibodies as Snakebite Antivenoms: Past and Future
Published in Toxins (01-09-2022)“…Snakebite envenomation is considered a neglected tropical disease, affecting tens of thousands of people each year. The recommended treatment is the use of…”
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Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo
Published in Biochimica et biophysica acta (01-10-2016)“…Cancer has long been associated with thrombosis and many of the standard chemotherapeutics used to treat cancer are pro-thrombotic. Thus, the identification of…”
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Design of bioactive peptides derived from CART sequence isolated from the toadfish Thalassophryne nattereri
Published in 3 Biotech (01-04-2020)“…© King Abdulaziz City for Science and Technology 2020 The emergence of bacterial resistance due to the indiscriminate use of antibiotics warrants the need for…”
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Effects of compounds from Passiflora edulis Sims f. flavicarpa juice on blood coagulation and on proteolytic enzymes
Published in Protein and peptide letters (01-05-2012)“…Passion fruit (Passiflora edulis Sims f. flavicarpa) is popularly known for its sedative and calming properties and is consumed as a fresh fruit or as a juice…”
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COVID-19 induces proatherogenic alterations in moderate to severe non-comorbid patients: A single-center observational study
Published in Blood cells, molecules, & diseases (01-12-2021)“…Patients with COVID-19 can be asymptomatic or present mild to severe symptoms, leading to respiratory and cardiovascular complications and death. Type 2…”
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Caissarolysin I (Bcs I), a new hemolytic toxin from the Brazilian sea anemone Bunodosoma caissarum: Purification and biological characterization
Published in Biochimica et biophysica acta (01-03-2006)“…Two cationic proteins, C1 and C3, were purified to homogeneity from the hemolytic fraction of the venom of Bunodosoma caissarum sea anemone. The purification…”
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Leptospira Infection Interferes with the Prothrombinase Complex Assembly during Experimental Leptospirosis
Published in Frontiers in microbiology (28-03-2017)“…Leptospirosis is a worldwide zoonotic and neglected infectious disease of human and veterinary concern, caused by pathogenic species. Although bleeding is a…”
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The Kallikrein Inhibitor from Bauhinia bauhinioides (BbKI) shows antithrombotic properties in venous and arterial thrombosis models
Published in Thrombosis research (01-05-2014)“…Abstract The Bauhinia bauhinioides Kallikrein Inhibitor (BbKI) is a Kunitz-type serine peptidase inhibitor of plant origin that has been shown to impair the…”
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Conformational changes of Loxosceles venom sphingomyelinases monitored by circular dichroism
Published in Biochemical and biophysical research communications (04-02-2005)“…Envenomation by arachnids of the genus Loxosceles can induce a variety of biological effects, including dermonecrosis and hemolysis. We have previously…”
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Structural insights into the catalytic mechanism of sphingomyelinases D and evolutionary relationship to glycerophosphodiester phosphodiesterases
Published in Biochemical and biophysical research communications (31-03-2006)“…Spider venom sphingomyelinases D catalyze the hydrolysis of sphingomyelin via an Mg2+ ion-dependent acid–base catalytic mechanism which involves two…”
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Management of Mercury Waste in an Institution of São Paulo State Health Secretary, the Case of Butantan Institute
Published in Orbital : The Electronic Journal of Chemistry (01-04-2015)“…Metallic mercury is a species of interest for public health and the environment due to its high toxicity. The activities related to health assistance are among…”
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Kinetic and mechanistic characterization of the Sphingomyelinases D from Loxosceles intermedia spider venom
Published in Toxicon (Oxford) (15-03-2006)“…Envenomation by arachnids of the genus Loxosceles leads to local dermonecrosis and serious systemic toxicity mainly induced by sphingomyelinases D (SMase D)…”
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A Prothrombin Activator Serine Protease from the Lonomia obliqua Caterpillar Venom (Lopap) : Biochemical Characterization
Published in Thrombosis research (01-06-2001)“…Lonomia obliqua venom causes a severe consumptive coagulopathy, which can lead to a hemorrhagic syndrome. The crude bristles extract displays a procoagulant…”
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Bauhinia proteinase inhibitor-based synthetic fluorogenic substrates for enzymes isolated from insect midgut and caterpillar bristles
Published in Biological chemistry (01-03-2003)“…Bauhinia ungulata factor Xa inhibitor (BuXI) inactivates factor Xa and LOPAP, a prothrombin activator proteinase isolated from the venom of Lonomia obliqua…”
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Allozyme diversity and morphometrics of Melocactus paucispinus (Cactaceae) and evidence for hybridization with M. concinnus in the Chapada Diamantina, North-eastern Brazil
Published in Annals of botany (01-03-2006)“…BACKGROUND AND AIMS: Melocacatus paucispinus (Cactaceae) is endemic to the state of Bahia, Brazil, and due to its rarity and desirability to collectors it has…”
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Segregação de Resíduos Químicos por Compatibilidade e Reatividade no Instituto Butantan
Published in Orbital : The Electronic Journal of Chemistry (01-01-2015)“…The chemical residues management plan at Instituto Butantan employs a combination of criteria that must be considered when working with such residues: inter…”
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A Prothrombin Activator Serine Protease from the Lonomia obliqua Caterpillar Venom (Lopap)
Published in Thrombosis research (01-06-2001)Get full text
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20
Design of bioactive peptides derived from CART sequence isolated from the toadfish Thalassophryne nattereri
Published in 3 Biotech (01-04-2020)“…The emergence of bacterial resistance due to the indiscriminate use of antibiotics warrants the need for developing new bioactive agents. In this context,…”
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