Search Results - "Andrés, Maria Estela"
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Type 2β Corticotrophin Releasing Factor Receptor Forms a Heteromeric Complex With Dopamine D1 Receptor in Living Cells
Published in Frontiers in pharmacology (08-01-2020)“…Corticotrophin releasing factor (CRF) and its related peptides differentially bind to CRF receptors to modulate stress-related behaviors. CRF receptors…”
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The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization
Published in Journal of neurochemistry (01-02-2019)“…Kappa‐opioid receptors (KOR) control dopamine (DA) levels in the striatum and contribute significantly to the progression of drug addiction. Repeated exposure…”
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Bioinformatic analysis predicts that ethanol exposure during early development causes alternative splicing alterations of genes involved in RNA post-transcriptional regulation
Published in PloS one (13-04-2023)“…Prenatal ethanol exposure is associated with neurodevelopmental defects and long-lasting cognitive deficits, which are grouped as fetal alcohol spectrum…”
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Unveiling RCOR1 as a rheostat at transcriptionally permissive chromatin
Published in Nature communications (23-03-2022)“…RCOR1 is a known transcription repressor that recruits and positions LSD1 and HDAC1/2 on chromatin to erase histone methylation and acetylation. However, there…”
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Study of the release of endogenous amines in Drosophila brain in vivo in response to stimuli linked to aversive olfactory conditioning
Published in Journal of neurochemistry (01-02-2021)“…A highly challenging question in neuroscience is to understand how aminergic neural circuits contribute to the planning and execution of behaviors, including…”
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Type 1 Corticotropin-Releasing Factor Receptor Differentially Modulates Neurotransmitter Levels in the Nucleus Accumbens of Juvenile versus Adult Rats
Published in International journal of molecular sciences (16-09-2022)“…Adversity is particularly pernicious in early life, increasing the likelihood of developing psychiatric disorders in adulthood. Juvenile and adult rats exposed…”
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Opposite effects of acute and chronic amphetamine on Nurr1 and NF-κB p65 in the rat ventral tegmental area
Published in Brain research (01-12-2016)“…Abstract Dopamine neurons are overstimulated by drugs of abuse and suffer molecular alterations that lead to addiction behavior. Nurr1 is a transcription…”
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Long 3'UTR of Nurr1 mRNAs is targeted by miRNAs in mesencephalic dopamine neurons
Published in PloS one (16-11-2017)“…The development of mesencephalic dopamine neurons and their survival later in life requires the continuous presence of the transcription factor Nurr1 (NR4A2)…”
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Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors
Published in Frontiers in pharmacology (18-02-2020)“…The strength of goal-oriented behaviors is regulated by midbrain dopamine neurons. Dysfunctions of dopaminergic circuits are observed in drug addiction and…”
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Revealing RCOR2 as a regulatory component of nuclear speckles
Published in Epigenetics & chromatin (24-11-2021)“…Nuclear processes such as transcription and RNA maturation can be impacted by subnuclear compartmentalization in condensates and nuclear bodies. Here, we…”
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Decreased Expression of CoREST1 and CoREST2 Together with LSD1 and HDAC1/2 during Neuronal Differentiation
Published in PloS one (25-06-2015)“…CoREST (CoREST1, rcor1) transcriptional corepressor together with the histone demethylase LSD1 (KDM1A) and the histone deacetylases HDAC1/2 form…”
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The effect of previous exposure to nicotine on nicotine place preference
Published in Psychopharmacology (01-04-2013)“…Rationale Prior exposure to drugs of abuse may increase or decrease the reinforcing effects of the drug in later consumptions. Based on the initial locomotor…”
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Optimization of the Light-On system in a lentiviral platform to a light-controlled expression of genes in neurons
Published in Electronic Journal of Biotechnology (01-05-2021)“…Molecular brain therapies require the development of molecular switches to control gene expression in a limited and regulated manner in time and space…”
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PIASγ enhanced SUMO-2 modification of Nurr1 activation-function-1 domain limits Nurr1 transcriptional synergy
Published in PloS one (2013)“…Nurr1 (NR4A2) is a transcription factor that belongs to the orphan NR4A group of the nuclear receptor superfamily. Nurr1 plays key roles in the origin and…”
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Immunolocalization of kappa opioid receptors in the axon initial segment of a group of embryonic mesencephalic dopamine neurons
Published in IBRO neuroscience reports (01-06-2022)“…The dopamine mesolimbic system is a major circuit involved in controlling goal-directed behaviors. Dopamine D2 receptors (D2R) and kappa opioid receptors (KOR)…”
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An Early Disturbance in Serotonergic Neurotransmission Contributes to the Onset of Parkinsonian Phenotypes in Drosophila melanogaster
Published in Cells (Basel, Switzerland) (05-05-2022)“…Parkinson's disease (PD) is a neurodegenerative disease characterized by motor symptoms and dopaminergic cell loss. A pre-symptomatic phase characterized by…”
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Development of a Bicistronic Vector for the Expression of a CRISPR/Cas9-mCherry System in Fish Cell Lines
Published in Cells (Basel, Switzerland) (21-01-2019)“…The clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) system has been widely used in animals as an efficient…”
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Pilocarpine-induced seizures associate with modifications of LSD1/CoREST/HDAC1/2 epigenetic complex and repressive chromatin in mice hippocampus
Published in Biochemistry and biophysics reports (01-03-2021)“…Epilepsy is a neurological disorder of genetic or environmental origin characterized by recurrent spontaneous seizures. A rodent model of temporal lobe…”
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Long-term loss of dopamine release mediated by CRF-1 receptors in the rat lateral septum after repeated cocaine administration
Published in Behavioural brain research (01-08-2013)“…•Activation of CRF-R1 in lateral septum (LS) increases dopamine extracellular levels.•Repeated exposure to cocaine suppresses the increase in LS dopamine…”
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CDNF induces the adaptive unfolded protein response and attenuates endoplasmic reticulum stress-induced cell death
Published in Biochimica et biophysica acta. Molecular cell research (01-11-2018)“…The Cerebral Dopamine Neurotrophic Factor (CDNF) is a neurotrophic factor that has a protective effect in cell and animal models of several neurodegenerative…”
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