Search Results - "André Luís Menezes Carvalho"
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Phenobarbital loaded microemulsion: development, kinetic release and quality control
Published in Brazilian Journal of Pharmaceutical Sciences (01-04-2016)“…ABSTRACT This study aimed to obtain and characterize a microemulsion (ME) containing phenobarbital (PB). The PB was incorporated in the proportion of 5% and…”
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2
Gallic and Ellagic Acids Are Promising Adjuvants to Conventional Amphotericin B for the Treatment of Cutaneous Leishmaniasis
Published in Antimicrobial agents and chemotherapy (17-11-2020)“…In this study, we demonstrated the potential associative effect of combining conventional amphotericin B (Amph B) with gallic acid (GA) and with ellagic acid…”
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3
In vitro bioactivity and cytotoxicity of films based on mesocarp of Orbignya sp. and carboxymethylcellulose as a tannic acid release matrix
Published in Carbohydrate polymers (01-12-2018)“…•Films based on mesocarp of Orbignya sp. (MB) and carboxymethylcellulose (CMC).•Bioactive films incorporating tannic acid (TA) into the polymer matrix.•The…”
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4
Amphotericin B-Loaded Emulgel: Effect of Chemical Enhancers on the Release Profile and Antileishmanial Activity In Vitro
Published in AAPS PharmSciTech (01-04-2019)“…Cutaneous leishmaniasis is a neglected parasitic disease. Treatment is preferably performed with pentavalent antimony associated or not with amphotericin B…”
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5
Synthesis of Polyglycerol/PolyCaprolactone Nanocopolymers as Innovative Architectures for Drug Delivery
Published in BioNanoScience (01-09-2024)“…Nanoparticles represent an innovative class of drug delivery systems that have gained increasing interest in nanotechnology applied to medicine. This study…”
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Evaluation of the in vivo leishmanicidal activity of amphotericin B emulgel: An alternative for the treatment of skin leishmaniasis
Published in Experimental parasitology (01-05-2016)“…The American Cutaneous Leishmaniasis (ACL) is an infectious disease that can be fatal. The first line of treatment is pentavalent antimonies. However, due to…”
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Pharmacological actions of bacuri butter (Platonia insignis Mart.): an integrative review
Published in Rev. RENE (04-01-2021)“…Objective: to identify the pharmacological activities of bacuri butter (Platonia insignis Mart.). Methods: an integrative review, carried out in the databases…”
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In vivo evaluation of anticonvulsant and antioxidant effects of phenobarbital microemulsion for transdermal administration in pilocarpine seizure rat model
Published in Pharmacology, biochemistry and behavior (01-04-2015)“…This study aimed to evaluate a microemulsion system (ME) containing phenobarbital in epilepsy model induced by pilocarpine in rats and to oxidative stress and…”
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Development of an Experimental Dentifrice with Hydroxyapatite Nanoparticles and High Fluoride Concentration to Manage Root Dentin Demineralization
Published in International journal of nanomedicine (01-01-2020)“…High-fluoride dentifrice is used to manage root caries, but there is no evidence whether its association with nanohydroxyapatite could provide an additional…”
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10
Chemical Characterization, Leishmanicidal Activity and In Vitro Cytotoxicity of the Essential Oil Extracted from Pectis brevipedunculata (Gardner) Sch.Bip. and Its Incorporation into Microemulsion Systems
Published in Pharmaceutics (09-01-2024)“…(Gardner) Sch.Bip., known in Brazil as alecrim do campo, is a small Asteraceae family plant with a calming effect and consumed as tea. This species contains…”
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Evaluation of the acute toxicity of ellagic acid and gallic acid incorporated in Poloxamer407® gel, in Zophobas morio larvae
Published in Toxicology in vitro (01-03-2024)“…Gallic acid (GA) has antioxidant, anti-inflammatory and antimicrobial properties, while ellagic acid (EA) demonstrates anticancer, antiviral and…”
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Validation of spectrophotometric methods for the simultaneous determination of fluconazole and riparin B in the development of lipid nanoparticles modified by β-cyclodextrin: Application for in vitro characterization and ex vivo studies of nail retention
Published in Microchemical journal (01-05-2024)“…[Display omitted] •The contents of fluconazole (FLC) and riparin B (RIP) in lipid nanoparticles were simultaneously determined.•Four spectrophotometric methods…”
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13
Innovative Microemulsion Loaded with Unusual Dimeric Flavonoids from Fridericia platyphylla (Cham.) L.G. Lohmann Roots
Published in AAPS PharmSciTech (17-10-2023)“…Fridericia platyphylla (Cham.) L.G. Lohmann is a species native to the Brazilian cerrado, with promising bioactivity. The organic fraction of the roots is rich…”
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Evaluation of Microemulsion and Lamellar Liquid Crystalline Systems for Transdermal Zidovudine Delivery
Published in Journal of pharmaceutical sciences (01-07-2016)“…This study proposed to investigate and to compare colloidal carrier systems containing Zidovudine (3'-azido-3'-deoxythymidine) (AZT) for transdermal…”
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Antileishmanial activity of Riparin structural analogs of Aniba riparia: Biological evaluation, in silico Adme-Tox, and molecular docking
Published in Experimental parasitology (01-05-2022)“…We performed a biological evaluation of antileishmanial activity, in silico ADME-Tox profile, and molecular docking of riparins A-F. The antileishmanial…”
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16
Development of Chlorhexidine Digluconate and Lippia sidoides Essential Oil Loaded in Microemulsion for Disinfection of Dental Root Canals: Substantivity Profile and Antimicrobial Activity
Published in AAPS PharmSciTech (04-11-2020)“…The dental intracanal disinfection is crucial to achieve the success of endodontic treatment, avoiding the maintenance of endodontic infections. Chlorhexidine…”
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17
Development of microemulsion of tamsulosin and dutasteride for benign prostatic hyperplasia therapy
Published in Colloids and surfaces, B, Biointerfaces (01-01-2020)“…[Display omitted] •Dutasteride (DU) and Tamsulosin (TA) was loaded in transdermal microemulsions.•A simultaneous quantification of DU and TA was developed by…”
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Third-Generation Transdermal Delivery Systems Containing Zidovudine: Effect of the Combination of Different Chemical Enhancers and a Microemulsion System
Published in AAPS PharmSciTech (01-10-2018)“…ABSTRACT This study aimed to examine the influence of the combination of chemical enhancers and a microemulsion on the transdermal permeation of zidovudine…”
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19
Emulgel based on amphotericin B and bacuri butter (Platonia insignis Mart.) for the treatment of cutaneous leishmaniasis: characterization and in vitro assays
Published in Drug development and industrial pharmacy (03-10-2018)“…Objective: This work aimed to develop and characterize a topical emulgel of amphotericin B (AmB) with bacuri butter (Platonia insignis Mart.) and evaluate its…”
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20
Use of antifungals in the treatment of vulvovaginal candidiasis: an integrative review
Published in Revista de Enfermagem da UFPI (13-12-2023)“…Objective: To identify scientific evidence available in the literature and analyze the action of antifungal drugs used for the treatment of vulvovaginal…”
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