Search Results - "Andleeb, Saadia"
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Bacterial biofilm and associated infections
Published in Journal of the Chinese Medical Association (01-01-2018)“…Microscopic entities, microorganisms that drastically affect human health need to be thoroughly investigated. A biofilm is an architectural colony of…”
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Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms
Published in PloS one (11-01-2017)“…In contrast to planktonic cells, bacteria imbedded biofilms are notoriously refractory to treatment by antibiotics or bacteriophage (phage) used alone. Given…”
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3
Prediction of vaccine candidates against Pseudomonas aeruginosa: An integrated genomics and proteomics approach
Published in Genomics (San Diego, Calif.) (01-07-2017)“…Pseudomonas aeruginosa is among top critical nosocomial infectious agents due to its persistent infections and tendency for acquiring drug resistance…”
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In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by Acinetobacter baumannii
Published in International journal of peptide research and therapeutics (01-01-2022)“…Acinetobacter baumannii is notorious for causing serious infections of the skin, lungs, soft tissues, bloodstream, and urinary tract. Despite the overwhelming…”
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5
Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance
Published in Communications biology (15-05-2020)“…Tetracycline resistance by antibiotic inactivation was first identified in commensal organisms but has since been reported in environmental and pathogenic…”
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Exploring the resistome, virulome, and mobilome of multidrug-resistant Klebsiella pneumoniae isolates: deciphering the molecular basis of carbapenem resistance
Published in BMC genomics (25-04-2024)“…Klebsiella pneumoniae, a notorious pathogen for causing nosocomial infections has become a major cause of neonatal septicemia, leading to high morbidity and…”
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Bacteriophages and their implications on future biotechnology: a review
Published in Virology journal (10-01-2012)“…Recently it has been recognized that bacteriophages, the natural predators of bacteria can be used efficiently in modern biotechnology. They have been proposed…”
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Methicillin resistant Staphylococcus aureus: A brief review of virulence and resistance
Published in Journal of the Pakistan Medical Association (01-03-2022)“…Staphylococcus aureus is a common gram-positive human pathogen involved in both community-acquired and nosocomial infections ranging from localised superficial…”
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Bacteriophages: an overview of the control strategies against multiple bacterial infections in different fields
Published in Journal of basic microbiology (01-02-2019)“…Bacteriophages (phages/viruses) need host bacteria to replicate and propagate. Primarily, a bacteriophage contains a head/capsid to encapsidate the genetic…”
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10
Spatiotemporal dynamics of multidrug resistant bacteria on intensive care unit surfaces
Published in Nature communications (08-10-2019)“…Bacterial pathogens that infect patients also contaminate hospital surfaces. These contaminants impact hospital infection control and epidemiology, prompting…”
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Navigating the brain: the role of exosomal shuttles in precision therapeutics
Published in Frontiers in neurology (18-01-2024)“…Brain diseases have become one of the leading roots of mortality and disability worldwide, contributing a significant part of the disease burden on healthcare…”
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12
Evaluation of Machine Learning and Rules-Based Approaches for Predicting Antimicrobial Resistance Profiles in Gram-negative Bacilli from Whole Genome Sequence Data
Published in Frontiers in microbiology (28-11-2016)“…The time-to-result for culture-based microorganism recovery and phenotypic antimicrobial susceptibility testing necessitates initial use of empiric (frequently…”
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13
Quest for Novel Preventive and Therapeutic Options Against Multidrug-Resistant Pseudomonas aeruginosa
Published in International journal of peptide research and therapeutics (01-12-2021)“…Pseudomonas aeruginosa ( P. aeruginosa ) is a critical healthcare challenge due to its ability to cause persistent infections and the acquisition of antibiotic…”
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14
KPC and NDM-1 genes in related Enterobacteriaceae strains and plasmids from Pakistan and the United States
Published in Emerging infectious diseases (01-06-2015)“…To characterize the genomic context of New Delhi metallo-β-lactamase-1 (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC), we sequenced 78…”
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Immunoinformatics Driven Prediction of Multiepitopic Vaccine Against Klebsiella pneumoniae and Mycobacterium tuberculosis Coinfection and Its Validation via In Silico Expression
Published in International journal of peptide research and therapeutics (01-06-2021)“…Klebsiella pneumonia e and Mycobacterium tuberculosis coinfection is one of the most lethal combinations that has been becoming frequent yet, not diagnosed and…”
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Intensive care unit sinks are persistently colonized with multidrug resistant bacteria and mobilizable, resistance-conferring plasmids
Published in mSystems (31-08-2023)“…Contamination of hospital sinks with microbial pathogens presents a serious potential threat to patients, but our understanding of sink colonization dynamics…”
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Antibiotic-mediated expression analysis of Shiga toxin 1 and 2 in multi-drug-resistant Shiga toxigenic Escherichia coli
Published in Folia microbiologica (01-10-2021)“…Shiga toxin-producing Escherichia coli (STEC) is an important foodborne pathogens, known to cause enteric infections especially diarrhea, mainly attributed…”
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Antimicrobial Resistance Profiling of Biofilm Forming Non Typhoidal Salmonella enterica Isolates from Poultry and Its Associated Food Products from Pakistan
Published in Antibiotics (Basel) (28-06-2021)“…Salmonellosis caused by non-typhoidal from poultry products is a major public health concern worldwide. This study aimed at estimating the pathogenicity and…”
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19
Association of hepatitis E seropositivity and altered progesterone levels in pregnant women of low socioeconomic status from capital region of Pakistan
Published in Journal of the Pakistan Medical Association (01-12-2020)“…To investigate the seroprevalence of hepatitis E virus infection, risk factors and its association with progesterone levels in pregnant women from low…”
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Draft genome sequence of an extensively drug-resistant neonatal Klebsiella pneumoniae isolate harbouring multiple plasmids contributing to antibiotic resistance
Published in Journal of global antimicrobial resistance. (01-12-2020)“…Klebsiella pneumoniae is a notorious nosocomial pathogen that has become a significant cause of neonatal infections causing morbidity and mortality. A…”
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