Search Results - "Andersson Svahn, Helene"

Droplet Microfluidics-A Tool for Single-Cell Analysis by Joensson, Haakan N., Andersson Svahn, Helene

“…Droplet microfluidics allows the isolation of single cells and reagents in monodisperse picoliter liquid capsules and manipulations at a throughput of…”
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High-throughput screening for industrial enzyme production hosts by droplet microfluidics by Sjostrom, Staffan L, Bai, Yunpeng, Huang, Mingtao, Liu, Zihe, Nielsen, Jens, Joensson, Haakan N, Andersson Svahn, Helene

“…A high-throughput method for single cell screening by microfluidic droplet sorting is applied to a whole-genome mutated yeast cell library yielding improved…”
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Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast by Huang, Mingtao, Bai, Yunpeng, Sjostrom, Staffan L., Hallström, Björn M., Liu, Zihe, Petranovic, Dina, Uhlén, Mathias, Joensson, Haakan N., Andersson-Svahn, Helene, Nielsen, Jens

“…There is an increasing demand for biotech-based production of recombinant proteins for use as pharmaceuticals in the food and feed industry and in industrial…”
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Droplet size influences division of mammalian cell factories in droplet microfluidic cultivation by Periyannan Rajeswari, Prem Kumar, Joensson, Haakan N., Andersson‐Svahn, Helene

“…The potential of using droplet microfluidics for screening mammalian cell factories has been limited by the difficulty in achieving continuous cell division…”
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Droplet size based separation by deterministic lateral displacement-separating droplets by cell--induced shrinking by Joensson, Haakan N, Uhlén, Mathias, Svahn, Helene Andersson

“…We present a novel method for passive separation of microfluidic droplets by size at high throughput using deterministic lateral displacement (DLD). We also…”
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Adenoviral detection by recombinase polymerase amplification and vertical flow paper microarray by Nybond, Susanna, Réu, Pedro, Rhedin, Samuel, Svedberg, Gustav, Alfvén, Tobias, Gantelius, Jesper, Svahn, Helene Andersson

“…Respiratory viral infections often mimic the symptoms of infections caused by bacteria; however, restricted and targeted administration of antibiotics is…”
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A 61% lighter cell culture dish to reduce plastic waste by Réu, Pedro, Svedberg, Gustav, Hässler, Lars, Möller, Björn, Andersson Svahn, Helene, Gantelius, Jesper

“…Cell culture is a ubiquitous and flexible research method. However, it heavily relies on plastic consumables generating millions of tonnes of plastic waste…”
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Point-of-care vertical flow allergen microarray assay: proof of concept by Chinnasamy, Thiruppathiraja, Segerink, Loes I, Nystrand, Mats, Gantelius, Jesper, Andersson Svahn, Helene

“…Sophisticated equipment, lengthy protocols, and skilled operators are required to perform protein microarray-based affinity assays. Consequently, novel tools…”
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Multiplex analysis of enzyme kinetics and inhibition by droplet microfluidics using picoinjectors by Sjostrom, Staffan L, Joensson, Haakan N, Svahn, Helene Andersson

“…Enzyme kinetics and inhibition is important for a wide range of disciplines including pharmacology, medicine and industrial bioprocess technology. We present a…”
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Multiple pathogen biomarker detection using an encoded bead array in droplet PCR by Periyannan Rajeswari, Prem Kumar, Soderberg, Lovisa M., Yacoub, Alia, Leijon, Mikael, Andersson Svahn, Helene, Joensson, Haakan N.

“…We present a droplet PCR workflow for detection of multiple pathogen DNA biomarkers using fluorescent color-coded Luminex® beads. This strategy enables…”
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Detection and Analysis of Low-Abundance Cell-Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets by Joensson, Haakan N, Samuels, Michael L, Brouzes, Eric R, Medkova, Martina, Uhlén, Mathias, Link, Darren R, Andersson-Svahn, Helene

“…Finding the few: Cell-surface proteins are useful disease biomarkers, but current high-throughput methods are limited to detecting cells expressing more than…”
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Levels of human proteins in plasma associated with acute paediatric malaria by Reuterswärd, Philippa, Bergström, Sofia, Orikiiriza, Judy, Lindquist, Elisabeth, Bergström, Sven, Andersson Svahn, Helene, Ayoglu, Burcu, Uhlén, Mathias, Wahlgren, Mats, Normark, Johan, Ribacke, Ulf, Nilsson, Peter

“…The intimate interaction between the pathophysiology of the human host and the biology of the Plasmodium falciparum parasite results in a wide spectrum of…”
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Automated analysis of dynamic behavior of single cells in picoliter droplets by Khorshidi, Mohammad Ali, Rajeswari, Prem Kumar Periyannan, Wählby, Carolina, Joensson, Haakan N, Andersson Svahn, Helene

“…We present a droplet-based microfluidic platform to automatically track and characterize the behavior of single cells over time. This high-throughput assay…”
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Health care workers' perceptions of point-of-care testing in a low-income country-A qualitative study in Southwestern Uganda by Rasti, Reza, Nanjebe, Deborah, Karlström, Jonas, Muchunguzi, Charles, Mwanga-Amumpaire, Juliet, Gantelius, Jesper, Mårtensson, Andreas, Rivas, Lourdes, Galban, Francesc, Reuterswärd, Philippa, Andersson Svahn, Helene, Alvesson, Helle M, Boum, 2nd, Yap, Alfvén, Tobias

“…Point-of-care (POC) tests have become increasingly available and more widely used in recent years. They have been of particular importance to low-income…”
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Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade by Eissler, Nina, Mao, Yumeng, Brodin, David, Reuterswärd, Philippa, Andersson Svahn, Helene, Johnsen, John Inge, Kiessling, Rolf, Kogner, Per

“…Removal of immuno-suppression has been reported to enhance antitumor immunity primed by checkpoint inhibitors. Although PD-1 blockade failed to control tumor…”
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Rapid Phenotypic Antibiotic Susceptibility Testing of Uropathogens Using Optical Signal Analysis on the Nanowell Slide by Veses-Garcia, Marta, Antypas, Haris, Löffler, Susanne, Brauner, Annelie, Andersson-Svahn, Helene, Richter-Dahlfors, Agneta

“…Achieving fast antimicrobial susceptibility results is a primary goal in the fight against antimicrobial resistance. Standard antibiotic susceptibility testing…”
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3D Bioprinting of Tissue/Organ Models by Pati, Falguni, Gantelius, Jesper, Svahn, Helene Andersson

“…In vitro tissue/organ models are useful platforms that can facilitate systematic, repetitive, and quantitative investigations of drugs/chemicals. The primary…”
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Multiplex detection of meningitis pathogens by a vertical flow paper microarray and signal enhancement suitable for low-resource settings: Proof of concept by Réu, Pedro, Gaudenzi, Giulia, Nanjebe, Deborah, Svedberg, Gustav, Nyehangane, Dan, Iturritza, Miren Urrutia, Mlotshwa, Phuthumani, Hadjineophytou, Chris, Karlsson, Jens, Gantelius, Jesper, Mwanga-Amumpaire, Juliet, Loh, Edmund, Svahn, Helene Andersson, Kumbakumba, Elias, Alfvén, Tobias, Boum II, Yap, Russom, Aman

“…•The vertical flow microarray (VFM) can detect multiple pathogens simultaneously.•The primers (sodC, hpd, lytA, and invA) amplified their targets with…”
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Lab on a chip technologies for bioenergy and biosustainability research by Uhlen, Mathias, Svahn, Helene Andersson

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Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis by Dias, Jorge T, Svedberg, Gustav, Nystrand, Mats, Andersson-Svahn, Helene, Gantelius, Jesper

“…The use of nanoprobes such as gold, silver, silica or iron-oxide nanoparticles as detection reagents in bioanalytical assays can enable high sensitivity and…”
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