Search Results - "Andersson, P.L"

P04-07 Physiologically based toxicokinetic modelling of bisphenols in zebrafish (Danio rerio) accounting for variation in metabolic rates, brain distribution and liver accumulation by Chelcea, I.C., Örn, S., Hamers, T., Koekkoek, J., Legradi, J., Vogs, C., Andersson, P.L.

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Application of conformal prediction for in silico definition of molecular initiating events linked to endocrine disruption by Sapounidou, M., Norinder, U., Andersson, P.L.

“…The adverse outcome pathway (AOP) paradigm has brought mechanism of action in the spotlight of regulatory toxicology, linking biochemical interactions on…”
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Modelling Toxicokinetics of BPA Analogues in Zebrafish by Chelcea, I., Örn, S., Hamers, T., Legradi, J., Vogs, C., Andersson, P.L.

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In Vitro Profiling of the Endocrine-Disrupting Potency of Brominated Flame Retardants by Hamers, Timo, Kamstra, Jorke H., Sonneveld, Edwin, Murk, Albertinka J., Kester, Monique H. A., Andersson, Patrik L., Legler, Juliette, Brouwer, Abraham

“…Over the last few years, increasing evidence has become available that some brominated flame retardants (BFRs) may have endocrine-disrupting (ED) potencies…”
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Conformal prediction to define applicability domain - A case study on predicting ER and AR binding by Norinder, U., Rybacka, A., Andersson, P.L.

“…A fundamental element when deriving a robust and predictive in silico model is not only the statistical quality of the model in question but, equally…”
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Removal of micropollutants and nutrients in household wastewater using organic and inorganic sorbents by Zhang, W., Blum, K., Gros, M., Ahrens, L., Jernstedt, H., Wiberg, K., Andersson, P.L., Björlenius, B., Renman, G.

“…The efficiency of five organic and five inorganic sorbents in removing 19 organic micropollutants (MPs), phosphorus, nitrogen, and dissolved organic carbon…”
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Non-dioxin-like PCBs inhibit [3H]WIN-35,428 binding to the dopamine transporter: A structure–activity relationship study by Wigestrand, M.B., Stenberg, M., Walaas, S.I., Fonnum, F., Andersson, P.L.

“…•PCB congeners inhibited WIN-35,428 binding to DAT.•We explored the structure–activity relationship.•Active PCBs were tetra- and penta-chlorinated with 2–3…”
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Activation and Potentiation of Human GABAA Receptors by Non-Dioxin–Like PCBs Depends on Chlorination Pattern by Antunes Fernandes, Elsa C., Hendriks, Hester S., van Kleef, Regina G. D. M., Reniers, Ad, Andersson, Patrik L., van den Berg, Martin, Westerink, Remco H. S.

“…The neurotoxic potential of non-dioxin-like polychlorinated biphenyls (NDL-PCBs) is characterized by disruption of presynaptic processes, including calcium…”
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Gender-specific proteomic responses in zebrafish liver following exposure to a selected mixture of brominated flame retardants by Kling, P., Norman, A., Andersson, P.L., Norrgren, L., Förlin, L.

“…Proteomic effect screening in zebrafish liver was performed to generate hypotheses following exposure (21 days) to a structurally diverse mixture of brominated…”
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Multivariate toxicity profiles and QSAR modeling of non-dioxin-like PCBs – An investigation of in vitro screening data from ultra-pure congeners by Stenberg, Mia, Hamers, Timo, Machala, Miroslav, Fonnum, Frode, Stenius, Ulla, Lauy, Al-Anati, van Duursen, Majorie B.M., Westerink, Remco H.S., Fernandes, Elsa C. Antunes, Andersson, Patrik L.

“…► NDL-PCBs have a complex spectrum of adverse effects but lack a risk assessment (RA). ► 21 Ultra-purified PCBs were screened in vitro for 28 different…”
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An overview of OSPAR priority compounds and selection of a representative training set by Knekta, E., Andersson, P.L., Johansson, M., Tysklind, M.

“…The aim of our study was to chemically characterize a set of priority substances in order to systematically select a representative set of heterogeneous…”
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Activation of Respiratory Burst in Human Granulocytes by Polychlorinated Biphenyls: A Structure–Activity Study by Voie, Ø.A., Tysklind, M., Andersson, P.L., Fonnum, F.

“…The respiratory burst in human granulocytes activated by 33 different congeners of polychlorinated biphenyls (PCBs) was measured as luminol-amplified…”
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The impact of musk ketone on reproduction in zebrafish ( Danio rerio) by Carlsson, G, Örn, S, Andersson, P.L, Söderström, H, Norrgren, L

“…Nitro musks are a group of nitrated benzenes mainly used by the fragrance industry as a substitute for natural musk. Two of the most common nitro musks, musk…”
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Effects of potential xenoestrogens (DEHP, nonylphenol and PCB) on sexual differentiation in juvenile Atlantic salmon (Salmo salar) by Norrgren, L., Blom, A., Andersson, P.L., Börjeson, H., Larsson, D.G.J., Olsson, P.-E.

“…The effects of 17β-estradiol and potential xenoestrogens were investigated on Atlantic salmon (Salmo salar). Juvenile salmon fed diets containing 15 and 30 mg…”
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Effects of potential xenoestrogens (DEHP, nonylphenol and PCB) on sexual differentiation in juvenile Atlantic salmon ( Salmo salar) by Norrgren, L., Blom, A., Andersson, P.L., Börjeson, H., Larsson, D.G.J., Olsson, P.-E.

“…The effects of 17β-estradiol and potential xenoestrogens were investigated on Atlantic salmon ( Salmo salar). Juvenile salmon fed diets containing 15 and 30 mg…”
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On the design and selection of polychlorinated biphenyls for use in biological test systems by Tysklind, M., Andersson, P.L., Van Bavel, B.

“…The polychlorinated biphenyls (PCBs) consist of a large number of individual congeners with varying degree of chlorination and possible substitution patterns…”
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