Search Results - "Andersson, Marine L"

Influence of CYP2C9 genotype on warfarin dose requirements--a systematic review and meta-analysis by Lindh, Jonatan D, Holm, Lennart, Andersson, Marine L, Rane, Anders

“…Purpose To quantify the influence of common cytochrome P450 2C9 (CYP2C9) polymorphisms on warfarin dose requirements. Methods A systematic review and a…”
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Pharmacological Risk Assessment Among Older Patients with Polypharmacy Using the Clinical Decision Support System Janusmed Risk Profile: A Cross-Sectional Register Study by Petersson, Ludvig, Schörgenhofer, Christian, Askfors, Ylva, Justad, Hanna, Dahl, Marja-Liisa, Andersson, Marine L.

“…Background Polypharmacy in older people is steadily increasing and a combination of many medicines may result in adverse effects, especially if the medicines…”
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Is tramadol associated to bleeding peptic ulcer? A nationwide case-control study in hospitalized Swedish patients by Järnbert-Pettersson, Hans, Andersson, Marine L, Bilén, Katarina, Broström, Olle, Lindh, Jonatan D, Mannheimer, Buster

“…Tramadol, a widely used analgesic drug, inhibits the reuptake of noradrenaline and serotonin impairing the aggregation function of thrombocytes. However, the…”
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High Prevalence of Drug–Drug Interactions in Primary Health Care is Caused by Prescriptions from other Healthcare Units by Andersson, Marine L., Böttiger, Ylva, Kockum, Henrik, Eiermann, Birgit

“…Drug–drug interactions are increasingly common, as patients are getting older and the number of drugs per patient is increasing. In this study, we investigated…”
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Drug-Drug Interactions in Patients with Acute Respiratory Distress Syndrome by Bischof, Thorsten, Schaller, Christoph, Buchtele, Nina, Staudinger, Thomas, Ullrich, Roman, Kraft, Felix, Andersson, Marine L, Jilma, Bernd, Schoergenhofer, Christian

“…Acute respiratory distress syndrome (ARDS) is a potential life-threatening, heterogenous, inflammatory lung disease. There are no data available on potential…”
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Clinical relevance of alerts from a decision support system, PHARAO, for drug safety assessment in the older adults by Hedna, Khedidja, Andersson, Marine L, Gyllensten, Hanna, Hägg, Staffan, Böttiger, Ylva

“…PHARAO is a decision support system developed to evaluate the risk for a set of either common or serious side-effects resulting from a combination of…”
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Patients' Use and Perceptions of a Drug-Drug Interaction Database: A Survey of Janusmed Interactions by Justad, Hanna, Askfors, Ylva, Shemeikka, Tero, Andersson, Marine L, Hammar, Tora

“…Janusmed interactions is a drug-drug interactions (DDI) database available online for healthcare professionals (HCP) at all levels of the healthcare system…”
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Adherence to guidelines for avoiding drug interactions associated with warfarin--a Nationwide Swedish Register Study by Lindh, Jonatan D, Andersson, Marine L, Mannheimer, Buster

“…To investigate the extent to which clinicians avoid well-established drug-drug interactions associated with warfarin. We hypothesised that clinicians would…”
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The effect of simvastatin on warfarin anticoagulation: a Swedish register-based nationwide cohort study by Andersson, Marine L., Mannheimer, Buster, Lindh, Jonatan D.

“…Purpose Some data indicate that simvastatin may increase the anticoagulative effect in patients treated with warfarin, but the evidence is scarce. The aim of…”
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Development and pilot testing of PHARAO—a decision support system for pharmacological risk assessment in the elderly by Böttiger, Ylva, Laine, Kari, Korhonen, Tuomas, Lähdesmäki, Janne, Shemeikka, Tero, Julander, Margaretha, Edlert, Maria, Andersson, Marine L.

“…Purpose The aims of this study are to describe the development of PHARAO (Pharmacological Risk Assessment Online), a decision support system providing a risk…”
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Cytochrome P450-Mediated Changes in Oxycodone Pharmacokinetics/Pharmacodynamics and Their Clinical Implications by Söderberg Löfdal, Karin C., Andersson, Marine L., Gustafsson, Lars L.

“…In recent years the use of the opioid oxycodone has increased markedly and replacing morphine as the first-line choice of opioid in several countries. There…”
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Seasonal Variation in Blood Drug Concentrations and a Potential Relationship to Vitamin D by LINDH, Jonatan D, ANDERSSON, Marine L, ELIASSON, Erik, BJORKHEM-BERGMAN, Linda

“…The most important enzyme in hepatic drug metabolism is cytochrome P450 3A4. Published in vitro data indicate that vitamin D may up-regulate the expression of…”
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SFINX--a drug-drug interaction database designed for clinical decision support systems by Böttiger, Ylva, Laine, Kari, Andersson, Marine L, Korhonen, Tuomas, Molin, Björn, Ovesjö, Marie-Louise, Tirkkonen, Tuire, Rane, Anders, Gustafsson, Lars L, Eiermann, Birgit

“…Objective The aim was to develop a drug-drug interaction database (SFINX) to be integrated into decision support systems or to be used in website solutions for…”
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A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C93 allele by Andersson, Marine L, Eliasson, Erik, Lindh, Jonatan D

“…Simvastatin interacts with warfarin, but the strength of the interaction varies between individual patients, indicating a genetic predisposition. The influence…”
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Evaluation of usage patterns and user perception of the drug–drug interaction database SFINX by Andersson, Marine L, Böttiger, Ylva, Bastholm-Rahmner, Pia, Ovesjö, Marie-Louise, Vég, Aniko, Eiermann, Birgit

“…Highlights • SFINX is used when prescribers and pharmacists meet patients. • Information, given by SFINX, results in changes in patient care. • Prescribers and…”
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Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet by Hoffmann, Mikael, Vander Stichele, Robert, Bates, David W, Björklund, Johanna, Alexander, Steve, Andersson, Marine L, Auraaen, Ane, Bennie, Marion, Dahl, Marja-Liisa, Eiermann, Birgit, Hackl, Werner, Hammar, Tora, Hjemdahl, Paul, Koch, Sabine, Kunnamo, Ilkka, Le Louët, Herve, Panagiotis, Papapetrou, Rägo, Lembit, Spedding, Michael, Seidling, Hanna M, Demner-Fushman, Dina, Gustafsson, Lars L

“…Technical and logical breakthroughs have provided new opportunities in medicine to use knowledge bases and large-scale clinical data (real-world) at…”
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Possible drug–drug interaction between quetiapine and lamotrigine – evidence from a Swedish TDM database by Andersson, Marine L., Björkhem‐Bergman, Linda, Lindh, Jonatan D.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Preliminary evidence from a single study indicates that co‐medication with lamotrigine may reduce the serum…”
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The continuing challenge of providing drug information services to diminish the knowledge—practice gap in medical practice by Alván, Gunnar, Andersson, Marine L., Asplund, Annika B., Böttiger, Ylva, Elwin, Carl-Eric, Gustafsson, Lars L., Öhman, Birgitta, Törnqvist, Elisabeth

“…Information must be collected, evaluated and utilized to support every qualified activity. Medicine, with a written scientific tradition stretching back more…”
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Potential Adverse Drug Events Identified with Decision Support Algorithms from Janusmed Risk Profile—A Retrospective Population-Based Study in a Swedish Region by Hammar, Tora, Jonsén, Emma, Björneld, Olof, Askfors, Ylva, Andersson, Marine L., Lincke, Alisa

“…Adverse drug events (ADEs) occur frequently and are a common cause of suffering, hospitalizations, or death, and can be caused by harmful combinations of…”
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The continuing challenge of providing drug information services to diminish the knowledgeâ[euro]"practice gap in medical practice by Alván, Gunnar, Andersson, Marine L, Asplund, Annika B, Böttiger, Ylva, Elwin, Carl-eric, Gustafsson, Lars L, Ã-hman, Birgitta, Törnqvist, Elisabeth

“…Issue Title: A tribute to Folke Sjöqvist, 80 Information must be collected, evaluated and utilized to support every qualified activity. Medicine, with a…”
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