Search Results - "Andersson, K.‐E."
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PDE5 inhibitors – pharmacology and clinical applications 20 years after sildenafil discovery
Published in British journal of pharmacology (01-07-2018)“…The discovery of the nitric oxide/cGMP pathway was the basis for our understanding of many normal physiological functions and the pathophysiology of several…”
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Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction
Published in Pharmacological reviews (01-12-2011)“…Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, both autonomic and somatic, and supraspinal influences from…”
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Purinergic signalling in the urinary bladder
Published in Autonomic neuroscience (01-09-2015)“…Abstract It is well established that in most species, exocytotic vesicular release of ATP from parasympathetic neurons contributes to contraction of the…”
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LUTS treatment: Future treatment options
Published in Neurourology and urodynamics (01-10-2007)“…Lower urinary tract symptoms (LUTS) are commonly divided into storage, voiding, and postmicturition symptoms, and may occur in both men and women. Male LUTS…”
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Pharmacology of Penile Erection
Published in Pharmacological reviews (01-09-2001)“…Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, but also by visual, olfactory, and imaginary stimuli. The…”
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Urethral afferent signalling: role of 5‐HT paraneurons
Published in Acta Physiologica (01-02-2018)Get full text
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Autonomic nervous control of the urinary bladder
Published in Acta Physiologica (01-01-2013)“…The autonomic nervous system plays an important role in the regulation of the urinary bladder function. Under physiological circumstances, noradrenaline,…”
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Phase II study on the efficacy and safety of the EP1 receptor antagonist ONO-8539 for nonneurogenic overactive bladder syndrome
Published in The Journal of urology (01-01-2014)“…We evaluated the efficacy, safety and tolerability of the EP1 receptor antagonist ONO-8539 in patients with overactive bladder syndrome. This was a 12-week,…”
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Antimuscarinics and the Overactive Detrusor—Which Is the Main Mechanism of Action?
Published in European Urology (2003)“…Contraction of the bladder, voluntary or involuntary, involves stimulation of the muscarinic receptors on the detrusor by acetylcholine, released from…”
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Targeting neurotrophin and nitric oxide signaling to promote recovery and ameliorate neurogenic bladder dysfunction following spinal cord injury – Mechanistic concepts and clinical implications
Published in Continence (Amsterdam) (01-06-2023)“…This review summarizes the presentations made to a workshop entitled “Targeting Neurotrophin and Nitric Oxide Signaling to Promote Recovery and Ameliorate…”
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Muscarinic acetylcholine receptors in the urinary tract
Published in Handbook of experimental pharmacology (2011)“…Muscarinic receptors comprise five cloned subtypes, encoded by five distinct genes, which correspond to pharmacologically defined receptors (M(1)-M(5)). They…”
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Immunohistochemical Distribution of cAMP- and cGMP-Phosphodiesterase (PDE) Isoenzymes in the Human Prostate
Published in European urology (01-04-2006)“…With the introduction of sildenafil citrate (VIAGRA™), the concept of phosphodiesterase (PDE) inhibition has gained tremendous interest in the field of…”
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Soluble Guanylate Cyclase Activators to Treat Benign Prostatic Hyperplasia and associated LUTS
Published in Continence (Amsterdam) (01-06-2023)“…This review summarises the presentations during a workshop session entitled “The Use of Soluble Guanylate Cyclase Activators to Treat Benign Prostatic…”
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14
Chemical Expansion Due to Hydration of Proton-Conducting Perovskite Oxide Ceramics
Published in Journal of the American Ceramic Society (01-08-2014)“…The crystal structures of proton‐conducting BaZr1−xYxO3−x/2 (BZY05–BZY20) and BaCe0.8Y0.2O2.9 (BCY20) during hydration/dehydration has been studied by in situ…”
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Current and future drugs for treatment of MS-associated bladder dysfunction
Published in Annals of physical and rehabilitation medicine (01-07-2014)“…Abstract A majority of patients diagnosed with multiple sclerosis (MS) will develop lower urinary tract symptoms (LUTS) during the course of the disease. Even…”
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Aquaporin expression in the fetal porcine urinary tract changes during gestation
Published in Physiological research (01-01-2018)“…The expression of aquaporins (AQPs) in the fetal porcine urinary tract and its relation to gestational age has not been established. Tissue samples from the…”
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Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c‐Jun N‐terminal kinase, SP600125 and BI‐78D3
Published in British journal of pharmacology (01-07-2012)“…BACKGROUND AND PURPOSE α1‐Adrenoceptor‐induced contraction of prostate smooth muscle is mediated by calcium‐ and Rho kinase‐dependent mechanisms. In addition,…”
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Animal models of erectile dysfunction (ED): potential utility of non-human primates as a model of atherosclerosis-induced vascular ED
Published in International journal of impotence research (01-05-2012)“…Erectile dysfunction (ED) is a prevalent medical condition affecting 18 million men and their sexual partners in the United States alone. In the majority of…”
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Complex Structure of Galaxy Cluster A1689: Evidence for a Merger from X-Ray Data?
Published in The Astrophysical journal (20-05-2004)“…A1689 is a galaxy cluster at z = 0.183 for which previous measurements of its mass by using various techniques gave discrepant results. We present a new…”
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Oats ( Avena sativa ) reduce atherogenesis in LDL-receptor-deficient mice
Published in Atherosclerosis (01-09-2010)“…Abstract Aim The cholesterol-lowering properties of oats, largely ascribed to its contents of soluble fibers, beta-glucans, are well established, whereas…”
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