Search Results - "Andersson, Carl Magnus"

thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans by Berkenstam, Anders, Kristensen, Jens, Mellström, Karin, Carlsson, Bo, Malm, Johan, Rehnmark, Stefan, Garg, Neeraj, Andersson, Carl Magnus, Rudling, Mats, Sjöberg, Folke, Angelin, Bo, Baxter, John D

“…Atherosclerotic cardiovascular disease is a major problem despite the availability of drugs that influence major risk factors. New treatments are needed, and…”
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Catalytic Antioxidant Activity of Diaryl Tellurides in a Two-Phase Lipid Peroxidation Model by Vessman, Kerstin, Ekstroem, Mikael, Berglund, Mats, Andersson, Carl-Magnus, Engman, Lars

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General combinatorial synthesis of tertiary amines on solid support. A novel conditional release strategy based on traceless linking at nitrogen by Gustafsson, Magnus, Olsson, Roger, Andersson, Carl-Magnus

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Synthesis, antioxidant properties, biological activity and molecular modelling of a series of chalcogen analogues of the 5-lipoxygenase inhibitor DuP 654 by Engman, Lars, Stern, David, Frisell, Håkan, Vessman, Kerstin, Berglund, Mats, Ek, Bengt, Andersson, Carl-Magnus

“…2-Phenylsulfenyl- ( 1b), 2-phenylselenenyl- ( 1c) and 2-phenyltellurenyl-1-naphthol ( 1d) were prepared and their antioxidative properties evaluated in…”
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Iron-Mediated Synthetic Routes to Unsymmetrically Substituted, Sterically Congested Benzophenones by Storm, J. Peter, Andersson, Carl-Magnus

“…A new synthetic route to unsymmetrically substituted benzophenones, relying upon iron-mediated reactions in all of the key steps, is described. The key buiding…”
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Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist by Vanover, Kimberly E, Harvey, Scott C, Son, Thomas, Bradley, Stefania Risso, Kold, Henriette, Makhay, Malath, Veinbergs, Isaac, Spalding, Tracy A, Weiner, David M, Andersson, Carl Magnus, Tolf, Bo-Ragnar, Brann, Mark R, Hacksell, Uli, Davis, Robert E

“…The primary purpose of the present series of experiments was to characterize the in vitro and in vivo pharmacology profile of…”
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An organoiron approach to thyroid hormone analogues by Smirnova, Joulia, Engman, Lars, Andersson, Carl-Magnus, Malm, Johan

“…Various approaches to thyroid hormone analogues based on sequential substitution of cationic cyclopentadienyl(1,4-dichlorobenzene)iron(II) complexes with…”
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Antioxidative properties of organotellurium compounds in cell systems by Wieslander, Elisabet, Engman, Lars, Svensjö, Erik, Erlansson, Magnus, Johansson, Ulf, Linden, Margareta, Andersson, Carl-Magnus, Brattsand, Ralph

“…The protective/antioxidative properties of diaryl tellurides were demonstrated in cellular systems of increasing complexity. In the presence of glutathione,…”
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Organotellurium compounds as efficient retarders of lipid peroxidation in methanol by Engman, Lars, Persson, Joachim, Vessman, Kerstin, Ekström, Mikael, Berglund, Mats, Andersson, Carl-Magnus

“…Diaryl tellurides were found efficiently to retard azo-initiated lipid peroxidation of linoleic acid in methanol. The most efficient compounds, 31 and 39,…”
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Solution-phase combinatorial synthesis via the olefin metathesis reaction by Boger, Dale L., Chai, Wenying, Ozer, Rachel S., Andersson, Carl-Magnus

“…The preparation of C 2-symmetric and unsymmetric chemical libraries by solution-phase techniques including the use of the olefin metathesis reaction to join…”
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Generation of targeted C2-symmetrical compound libraries by solution-phase combinatorial chemistry by Boger, Dale L., Ozer, Rachel S., Andersson, Carl-Magnus

“…An approach to the preparation of C 2-symmetrical chemical libraries for use in protein and receptor homodimerization studies by solution-phase methods which…”
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Higher order iminodiacetic acid libraries for probing protein–protein interactions by Boger, Dale L., Goldberg, Joel, Jiang, Weiqin, Chai, Wenying, Ducray, Pierre, Lee, Jae Kyoo, Ozer, Rachel S., Andersson, Carl-Magnus

“…Full details of the preparation of iminodiacetic acid diamide dimer (2040 compounds), trimer (560 compounds), and tetramer (1596 compounds) libraries by…”
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An Organoiron Approach to the Benzophenone Appendage of the Protein Kinase C Inhibitor Balanol by Storm, J. Peter, Andersson, Carl-Magnus

“…A new synthetic route to the benzophenone appendage of balanol, based on sequential iron-assisted nucleophilic aromatic substitution and ring-opening as well…”
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Preparation of Cationic Cyclopentadienyl Diene Molybdenum Complexes through Hydride Abstraction Effected by Di- or Triarylmethyl Halides in the Presence of Hexafluoro-2-propanol by Bjurling, Emelie, Björkman, Anders, Andersson, Carl-Magnus

“…Hydride abstraction from the model system (η5-cyclopentadienyl)dicarbonyl[(1−3-η)-1-cyclohexen-3-yl]molybdenum (1) was effected using halides such as Ph3CCl…”
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Synthesis of N-(2-Pyranyl)- and N-Cyclohexylindole Derivatives via Stereoselective Addition of Indole Nucleophiles to Organomolybdenum Complexes by Bjurling, Emelie, Johansson, Maria H, Andersson, Carl-Magnus

“…Indol-1-yl-substituted dihydropyranyl- and cyclohexenylmolybdenum complexes were obtained via nucleophilic addition of a variety of substituted indoles to…”
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Multistep solution-Phase parallel synthesis of spiperone analogues by Hansen, Henrik C., Olsson, Roger, Croston, Glenn, Andersson, Carl-Magnus

“…A flexible, multistep parallel synthesis of spiperone analogues is described. A library of 4-substituted piperidines, assembled utilizing reductive amination…”
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Diaryl tellurides as inhibitors of lipid peroxidation in biological and chemical systems by Andersson, C M, Brattsand, R, Hallberg, A, Engman, L, Persson, J, Moldéus, P, Cotgreave, I

“…Diaryl tellurides carrying electron-donating substituents in the para positions were found to efficiently inhibit peroxidation of rat hepatocytes, rat liver…”
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Antioxidant activity of some diarylselenides in biological systems by Andersson, C M, Hallberg, A, Linden, M, Brattsand, R, Moldéus, P, Cotgreave, I

“…The selenoorganic compounds di(4-aminophenyl)selenide (10) and 4-nitro-4'-amino-diphenylselenide (36) were shown to inhibit lipid peroxidation in…”
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Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist by Vanover, Kimberly E, Weiner, David M, Makhay, Malath, Veinbergs, Isaac, Gardell, Luis R, Lameh, Jelveh, Del Tredici, Andria L, Piu, Fabrice, Schiffer, Hans H, Ott, Thomas R, Burstein, Ethan S, Uldam, Allan K, Thygesen, Mikkel B, Schlienger, Nathalie, Andersson, Carl Magnus, Son, Thomas Y, Harvey, Scott C, Powell, Susan B, Geyer, Mark A, Tolf, Bo-Ragner, Brann, Mark R, Davis, Robert E

“…The in vitro and in vivo pharmacological properties of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide…”
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Solution-Phase Parallel Wittig Olefination:  Synthesis of Substituted 1,2-Diarylethanes by Husemoen, Gitte, Olsson, Roger, Andersson, Carl-Magnus, Harvey, Scott C., Hansen, Henrik C.

“…An efficient strategy for solution-phase parallel synthesis of substituted 1,2-diarylethanes is described. A stilbene library was initially generated by Wittig…”
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