Search Results - "Andersson, C. K."
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Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model
Published in Nature communications (06-02-2023)“…Interstitial lung diseases such as idiopathic pulmonary fibrosis (IPF) are caused by persistent micro-injuries to alveolar epithelial tissues accompanied by…”
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Novel site-specific mast cell subpopulations in the human lung
Published in Thorax (01-04-2009)“…Lung mast cells are stereotypically divided into connective tissue (MC(TC)) and mucosal (MC(T)) mast cells. This study tests the hypothesis that each of these…”
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Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma
Published in Clinical and experimental allergy (01-02-2014)“…Summary Background The toll‐like receptors, TLR5 and TLR7, have recently been proposed in asthma immunopathogenesis. While supporting data come from animal or…”
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Uncontrolled asthmatics have increased FceRI+ and TGF‐β–positive MCTC mast cells and collagen VI in the alveolar parenchyma
Published in Clinical and experimental allergy (01-03-2018)“…Summary Background Asthma has been associated with increased collagen deposition in both conducting airways and alveolar parenchyma. Mast cells (MCs) are key…”
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Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation
Published in Clinical and experimental allergy (01-02-2016)“…Summary Background Airway hyperresponsiveness (AHR) to inhaled mannitol is associated with indirect markers of mast cell activation and eosinophilic airway…”
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Uncontrolled asthmatics have increased FceRI + and TGF-β-positive MC TC mast cells and collagen VI in the alveolar parenchyma
Published in Clinical and experimental allergy (01-03-2018)“…Asthma has been associated with increased collagen deposition in both conducting airways and alveolar parenchyma. Mast cells (MCs) are key effector cells in…”
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Alveolar mast cells shift to an FcεRI‐expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology
Published in Allergy (Copenhagen) (01-12-2011)“…To cite this article: Andersson CK, Tufvesson E, Aronsson D, Bergqvist A, Mori M, Bjermer L, Erjefält JS. Alveolar mast cells shift to an FcεRI‐expressing…”
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C26 ASTHMA IN INFANTS AND CHILDREN: Lower Respiratory Tract Viral Infections In Children Cause Infiltration Of Mast Cells In To The Alveolar Parenchyma - Role In Asthma Development?
Published in American journal of respiratory and critical care medicine (01-01-2017)“…Lung tissue from 22 infants who died in respiratory syncytial virus (RSV: n=5), adenovirus (ADV: n=11) and influenza infections (n=6) was processed for…”
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Appearance of remodelled and dendritic cell-rich alveolar-lymphoid interfaces provides a structural basis for increased alveolar antigen uptake in chronic obstructive pulmonary disease
Published in Thorax (01-06-2013)“…The alveolar pathology in chronic obstructive pulmonary disease (COPD) involves antigen-driven immune events. However, the induction sites of alveolar adaptive…”
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Alveolar mast cells shift to an Fc[epsilon]RI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology
Published in Allergy (Copenhagen) (01-12-2011)“…Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (Fc[straight epsilon]RI) expression. Recent discoveries in…”
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Alterations in Lung Mast Cell Populations in Patients with Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-02-2010)“…Mast cells have important roles in innate immunity and tissue remodeling but have remained poorly studied in inflammatory airway diseases like chronic…”
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Mice Lacking 12/15-Lipoxygenase Have Attenuated Airway Allergic Inflammation and Remodeling
Published in American journal of respiratory cell and molecular biology (01-12-2008)“…Arachidonate 15-lipoxygenase (LO)-1 has been implicated in allergic inflammation and asthma. The overall effect of 15-LO in allergic inflammation in vivo is,…”
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