Search Results - "Anderson, Virginia E"

Topoisomerase IV Catalysis and the Mechanism of Quinolone Action by Anderson, V E, Gootz, T D, Osheroff, N

“…Topoisomerase IV is a bacterial type II topoisomerase that is essential for proper chromosome segregation and is a target for quinolone-based antimicrobial…”
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Action of Quinolones against Staphylococcus aureus Topoisomerase IV:  Basis for DNA Cleavage Enhancement by Anderson, Virginia E, Zaniewski, Richard P, Kaczmarek, Frank S, Gootz, Thomas D, Osheroff, Neil

“…Topoisomerase IV is the primary cellular target for most quinolones in Gram-positive bacteria; however, its interaction with these agents is poorly understood…”
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Quinolones Inhibit DNA Religation Mediated by Staphylococcus aureus Topoisomerase IV by Anderson, Virginia E., Zaniewski, Richard P., Kaczmarek, Frank S., Gootz, Thomas D., Osheroff, Neil

“…Quinolones are the most active oral antibacterials in clinical use and act by increasing DNA cleavage mediated by prokaryotic type II topoisomerases. Although…”
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Type II topoisomerases as targets for quinolone antibacterials: turning Dr. Jekyll into Mr. Hyde by Anderson, V E, Osheroff, N

“…Quinolones are a very important family of antibacterial agents that are widely prescribed for the treatment of infections in humans. Although the founding…”
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Quinolones inhibit DNA religation mediated by Staphylococcus aureus topoisomerase IV. Changes in drug mechanism across evolutionary boundaries by Anderson, V E, Zaniewski, R P, Kaczmarek, F S, Gootz, T D, Osheroff, N

“…Quinolones are the most active oral antibacterials in clinical use and act by increasing DNA cleavage mediated by prokaryotic type II topoisomerases. Although…”
Get full text