Search Results - "Anderson, V."
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Primary Cilia and Mammalian Hedgehog Signaling
Published in Cold Spring Harbor perspectives in biology (01-05-2017)“…It has been a decade since it was discovered that primary cilia have an essential role in Hedgehog (Hh) signaling in mammals. This discovery came from screens…”
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Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-2014)“…Centrosomes are the microtubule-organizing centers of animal cells that organize interphase microtubules and mitotic spindles. Centrioles are the…”
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Climate change, wine, and conservation
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2013)“…Climate change is expected to impact ecosystems directly, such as through shifting climatic controls on species ranges, and indirectly, for example through…”
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The Spinocerebellar Ataxia-Associated Gene Tau Tubulin Kinase 2 Controls the Initiation of Ciliogenesis
Published in Cell (09-11-2012)“…The primary cilium has critical roles in human development and disease, but the mechanisms that regulate ciliogenesis are not understood. Here, we show that…”
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Weed-induced crop yield loss: a new paradigm and new challenges
Published in Trends in plant science (01-05-2023)“…A commonly held misconception is that weeds reduce crop yield primarily because of resource competition.Weed presence reduces crop yield regardless of resource…”
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Cilia and Hedgehog Responsiveness in the Mouse
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2005)“…The intraflagellar transport (IFT) proteins Ift172/Wimple and Polaris/Ift88 and the anterograde IFT motor kinesin-II are required for the production and…”
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Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation
Published in Nature cell biology (01-12-2016)“…During gastrulation of the mouse embryo, individual cells ingress in an apparently stochastic pattern during the epithelial-to-mesenchymal transition (EMT)…”
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Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
Published in Development (Cambridge) (01-01-2006)“…Although the framework of the Hedgehog (Hh) signaling pathway is evolutionarily conserved, recent studies indicate that fundamental differences exist between…”
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Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube
Published in Development (Cambridge) (15-11-2011)“…Protein kinase A (PKA) is an evolutionarily conserved negative regulator of the hedgehog (Hh) signal transduction pathway. PKA is known to be required for the…”
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How Do the Flow Components of Coronary Flow Reserve Change After Aortic Valve Replacement?
Published in The American journal of cardiology (01-04-2024)Get full text
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Genomic prediction for agronomic traits in a diverse Flax (Linum usitatissimum L.) germplasm collection
Published in Scientific reports (08-02-2024)“…Breeding programs require exhaustive phenotyping of germplasms, which is time-demanding and expensive. Genomic prediction helps breeders harness the diversity…”
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Cilia and developmental signaling
Published in Annual review of cell and developmental biology (01-01-2007)“…Recent studies have revealed unexpected connections between the mammalian Hedgehog (Hh) signal transduction pathway and the primary cilium, a microtubule-based…”
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Lineage specificity of primary cilia in the mouse embryo
Published in Nature cell biology (01-02-2015)“…Primary cilia are required for vertebrate cells to respond to specific intercellular signals. Here we define when and where primary cilia appear in the mouse…”
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The Graded Response to Sonic Hedgehog Depends on Cilia Architecture
Published in Developmental cell (01-05-2007)“…Several studies have linked cilia and Hedgehog signaling, but the precise roles of ciliary proteins in signal transduction remain enigmatic. Here we describe a…”
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Activity analysis of construction equipment using audio signals and support vector machines
Published in Automation in construction (01-09-2017)“…In the construction industry, especially for civil infrastructure projects, a large portion of overall project expenses are allocated towards various costs…”
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rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline
Published in PLoS genetics (01-08-2017)“…Transcriptional silencing by heritable cytosine-5 methylation is an ancient strategy to repress transposable elements. It was previously thought that mammals…”
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p120-catenin regulates WNT signaling and EMT in the mouse embryo
Published in Proceedings of the National Academy of Sciences - PNAS (20-08-2019)“…Epithelial-to-mesenchymal transitions (EMTs) require a complete reorganization of cadherin-based cell–cell junctions. p120-catenin binds to the cytoplasmic…”
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β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo
Published in Nature communications (27-11-2020)“…Coordinated directional migration of cells in the mesoderm layer of the early embryo is essential for organization of the body plan. Here we show that mesoderm…”
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ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2
Published in eLife (23-01-2018)“…Mechanisms regulating mammalian meiotic progression are poorly understood. Here we identify mouse YTHDC2 as a critical component. A screen yielded a sterile…”
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Toll signaling pathways in the innate immune response
Published in Current opinion in immunology (01-02-2000)“…The Toll signaling pathway, which is required for the establishment of the dorsal-ventral axis in Drosophila embryos, plays an important role in the response…”
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