Search Results - "Anderson, Stephanie A"

HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation by Boasso, Adriano, Hardy, Andrew W, Anderson, Stephanie A, Dolan, Matthew J, Shearer, Gene M

“…Infection by the human immunodeficiency virus (HIV) is characterized by functional impairment and chronic activation of T lymphocytes, the causes of which are…”
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CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms by Mangano, Andrea, Lloyd, Andrew, Ahuja, Sunil K, O'Connell, Robert J, Anaya, Juan-Manuel, Miura, Toshiyuki, Mamtani, Manju, Anderson, Stephanie A, Bologna, Rosa, Pereyra, Florencia, Agan, Brian K, Sen, Luisa, Delmar, Judith, Martin, Jeffrey, Marconi, Vincent, Kulkarni, Hemant, He, Weijing, Walker, Bruce D, Smith, Alison, Ahuja, Seema S, Dolan, Matthew J, Deeks, Steven G, Hecht, Frederick M, Camargo, Jose F, Clark, Robert A

“…Although host defense against human immunodeficiency virus 1 (HIV-1) relies mainly on cell-mediated immunity (CMI), the determinants of CMI in humans are…”
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Differential Expression of IFN-α and TRAIL/DR5 in Lymphoid Tissue of Progressor versus Nonprogressor HIV-1-Infected Patients by Herbeuval, Jean-Philippe, Nilsson, Jakob, Boasso, Adriano, Hardy, Andrew W., Kruhlak, Michael J., Anderson, Stephanie A., Dolan, Matthew J., Dy, Michel, Andersson, Jan, Shearer, Gene M.

“…Loss of$CD4^{+}$T cells, the hallmark of HIV pathogenesis, was suggested to be partly due to apoptosis. We recently reported that IFN-α produced by…”
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Regulation of TNF-Related Apoptosis-Inducing Ligand on Primary CD4+T Cells by HIV-1: Role of Type I IFN-Producing Plasmacytoid Dendritic Cells by Herbeuval, Jean-Philippe, Hardy, Andrew W., Boasso, Adriano, Anderson, Stephanie A., Dolan, Matthew J., Dy, Michel, Shearer, Gene M., Sela, Michael

“…TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, was suggested to contribute to HIV-1 pathogenesis by inducing CD4+T cell death…”
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HIV-1 Infection and AIDS Dementia Are Influenced by a Mutant MCP-1 Allele Linked to Increased Monocyte Infiltration of Tissues and MCP-1 Levels by Gonzalez, Enrique, Rovin, Brad H., Sen, Luisa, Cooke, Glen, Dhanda, Rahul, Mummidi, Srinivas, Kulkarni, Hemant, Bamshad, Michael J., Telles, Vanessa, Anderson, Stephanie A., Walter, Elizabeth A., Stephan, Kevin T., Deucher, Michael, Mangano, Andrea, Bologna, Rosa, Ahuja, Seema S., Dolan, Matthew J., Ahuja, Sunil K.

“…Studies in humans and in experimental models of HIV-1 infection indicate an important role for monocyte chemoattractant protein-1 (MCP-1; also known as CC…”
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CNVs cause autosomal recessive genetic diseases with or without involvement of SNV/indels by Yuan, Bo, Wang, Lei, Liu, Pengfei, Shaw, Chad, Dai, Hongzheng, Cooper, Lance, Zhu, Wenmiao, Anderson, Stephanie A., Meng, Linyan, Wang, Xia, Wang, Yue, Xia, Fan, Xiao, Rui, Braxton, Alicia, Peacock, Sandra, Schmitt, Eric, Ward, Patricia A., Vetrini, Francesco, He, Weimin, Chiang, Theodore, Muzny, Donna, Gibbs, Richard A., Beaudet, Arthur L., Breman, Amy M., Smith, Janice, Cheung, Sau Wai, Bacino, Carlos A., Eng, Christine M., Yang, Yaping, Lupski, James R., Bi, Weimin

“…Improved resolution of molecular diagnostic technologies enabled detection of smaller sized exonic level copy-number variants (CNVs). The contribution of CNVs…”
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HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells by Boasso, Adriano, Herbeuval, Jean-Philippe, Hardy, Andrew W., Anderson, Stephanie A., Dolan, Matthew J., Fuchs, Dietmar, Shearer, Gene M.

“…Infection with the human immunodeficiency virus type-1 (HIV) results in acute and progressive numeric loss of CD4+ T-helper cells and functional impairment of…”
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Sensitivity of the Multispot HIV-1/HIV-2 Rapid Test Using Samples from Human Immunodeficiency Virus Type 1-Positive Individuals with Various Levels of Exposure to Highly Active Antiretroviral Therapy by O'Connell, Robert J, Agan, Brian K, Anderson, Stephanie A, Malia, Jennifer A, Michael, Nelson L

“…The Multispot HIV-1/HIV-2 rapid test detects human immunodeficiency virus type 1 (HIV-1) gp41 antibodies, which can wane over time in some HIV-1-infected…”
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Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility by Gonzalez, Enrique, Kulkarni, Hemant, Bolivar, Hector, Mangano, Andrea, Sanchez, Racquel, Catano, Gabriel, Nibbs, Robert J, Freedman, Barry I, Quinones, Marlon P, Bamshad, Michael J, Murthy, Krishna K, Rovin, Brad H, Bradley, William, Clark, Robert A, Anderson, Stephanie A, O'Connell, Robert J, Agan, Brian K, Ahuja, Seema S, Bologna, Rosa, Sen, Luisa, Dolan, Matthew J, Ahuja, Sunil K

“…Segmental duplications in the human genome are selectively enriched for genes involved in immunity, although the phenotypic consequences for host defense are…”
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TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1–infected patients and its in vitro production by antigen-presenting cells by Herbeuval, Jean-Philippe, Boasso, Adriano, Grivel, Jean-Charles, Hardy, Andrew W., Anderson, Stephanie A., Dolan, Matthew J., Chougnet, Claire, Lifson, Jeffrey D., Shearer, Gene M.

“…There is now considerable in vitro evidence that tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) is involved in HIV-1 pathogenesis by…”
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PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: Restricted expression of type I interferon receptor by CCR5-expressing leukocytes by Boasso, Adriano, Hardy, Andrew W, Landay, Alan L, Martinson, Jeffrey L, Anderson, Stephanie A, Dolan, Matthew J, Clerici, Mario, Shearer, Gene M

“…Abstract The programmed death (PD)-1 interacts with its ligand (PDL-1) delivering a negative signal to T cells. During human immunodeficiency virus (HIV)-1…”
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Global Survey of Genetic Variation in CCR5, RANTES, and MIP-1α: Impact on the Epidemiology of the HIV-1 Pandemic by Gonzalez, Enrique, Dhanda, Rahul, Bamshad, Mike, Mummidi, Srinivas, Geevarghese, Reni, Catano, Gabriel, Anderson, Stephanie A., Walter, Elizabeth A., Stephan, Kevin T., Hammer, Michael F., Mangano, Andrea, Sen, Luisa, Clark, Robert A., Ahuja, Seema S., Dolan, Matthew J., Ahuja, Sunil K.

“…Expression of CC chemokine receptor 5 (CCR5), the major coreceptor for HIV-1 cell entry, and its ligands (e.g., RANTES and MIP-1α) is widely regarded as…”
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Influenza Virus-Stimulated Generation of Anti-Human Immunodeficiency Virus (HIV) Activity after Influenza Vaccination in HIV-Infected Individuals and Healthy Control Subjects by Pinto, Ligia A., Blazevic, Vesna, Anderson, Stephanie A., Venzon, David J., Mac Trubey, C., Rowe, Thomas, Katz, Jacqueline M., Liewehr, David, Dolan, Matthew J., Shearer, Gene M.

“…Influenza virus stimulation of leukocytes induces factors that suppress human immunodeficiency virus (HIV). The effect of influenza vaccination on…”
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Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression by Mummidi, Srinivas, Ahuja, Seema S, Gonalez, Enrique, Anderson, Stephanie A, Santiago, Elvin N, Stephan, Kevin T, Craig, Fiona E, O'Connell, Peter, Tryon, Victor, Clark, Robert A, Dolan, Matthew J, Ahuja, Sunil K

“…Allelic variants for the HIV-1 co-receptors chemokine receptor 5 (CCR5) and CCR2, as well as the ligand for the co-receptor CXCR4, stromal-derived factor…”
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Race-Specific HIV-1 Disease-Modifying Effects Associated with CCR5 Haplotypes by Gonzalez, Enrique, Bamshad, Mike, Sato, Naoko, Mummidi, Srinivas, Dhanda, Rahul, Catano, Gabriel, Cabrera, Sonia, McBride, Megan, Cao, Xuan-Hien, Merrill, Gerald, O'Connell, Peter, Bowden, Donald W., Freedman, Barry I., Anderson, Stephanie A., Walter, Elizabeth A., Evans, James S., Stephan, Kevin T., Clark, Robert A., Tyagi, Sanjay, Ahuja, Seema S., Dolan, Matthew J., Ahuja, Sunil K.

“…Genetic variation in CC chemokine receptor 5 (CCR5), the major HIV-1 coreceptor, has been shown to influence HIV-1 transmission and disease progression…”
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Unexpected Chromosomal Abnormalities Identified by CMA Confirmation Studies by Cheung, Sau W, Pursley, Amber N, Ladha, Farah A, Song, Roger H, Anderson, Stephanie A, Cooper, M. Lance, Shaw, Chad, Bacino, Carlos A, Patel, Ankita

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28-day toxicology test: indenopyridine RTI 4587-056 in male Sprague–Dawley rats by Fail, Patricia A, Anderson, Stephanie A, Cook, C.Edgar

“…The potential toxicity of RTI 4587-056, a hexahydroindenopyridine analog of SANDOZ 20-438, was examined in adult male Sprague–Dawley rats. Testicular,…”
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Structure-Activity Studies of 2,3,4,4a,5,9b-Hexahydroindeno[1,2-c]pyridines as Antispermatogenic Agents for Male Contraception by Cook, C. Edgar, Wani, Mansukh C, Jump, Joseph M, Lee, Yue-W, Fail, Patricia A, Anderson, Stephanie A, Gu, Yu-Q, Petrow, Vladimir

“…Analogs of (4aRS,5SR,9bRS)-2-ethyl-2,3,4,4a,5,9b-hexahydro-7-meth yl-5-p- tolyl-1H-indeno[1,2-c]pyridine (Sandoz 20-438, 10a; R1 = ethyl, R2 = R3 = methyl, R4…”
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Anti-CCR5 antibodies in sera of HIV-positive individuals by Grene, Edith, Pinto, Ligia A, Landay, Alan L, Kessler, Harold A, Anderson, Stephanie A, Dolan, Matthew J, Shearer, Gene M

“…One of the proposed mechanisms for resistance to human immunodeficiency virus-1 (HIV-1) infection is the presence of antibodies against receptor for…”
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Induction of Antibodies to the Human Immunodeficiency Virus Type 1 by Immunization of Baboons with Immunoglobulin Molecules Carrying the Principal Neutralizing Determinant of the Envelope Protein by Zaghouani, Habib, Anderson, Stephanie A., Sperber, Kirk E., Daian, Christina, Kennedy, Ronald C., Mayer, Lloyd, Bona, Constantin A.

“…The hypervariable region 3 (V3) within the disulfide-bridged loop of the envelope protein of the human immunodeficiency virus type 1 (HIV-1) contains an amino…”
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