Search Results - "Anderson, Rhona M"

TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription by Gómez-Herreros, Fernando, Zagnoli-Vieira, Guido, Ntai, Ioanna, Martínez-Macías, María Isabel, Anderson, Rhona M., Herrero-Ruíz, Andrés, Caldecott, Keith W.

“…DNA double-strand breaks (DSBs) induced by abortive topoisomerase II (TOP2) activity are a potential source of genome instability and chromosome translocation…”
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Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform by Bikkul, Mehmet U., Faragher, Richard G. A., Worthington, Gemma, Meinke, Peter, Kerr, Alastair R. W., Sammy, Aakila, Riyahi, Kumars, Horton, Daniel, Schirmer, Eric C., Hubank, Michael, Kill, Ian R., Anderson, Rhona M., Slijepcevic, Predrag, Makarov, Evgeny, Bridger, Joanna M.

“…Immortalizing primary cells with human telomerase reverse transcriptase (hTERT) has been common practice to enable primary cells to be of extended use in the…”
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Cellular Senescence - its role in cancer and the response to ionizing radiation by Sabin, Rebecca J, Anderson, Rhona M

“…Cellular senescence is a normal biological process that is initiated in response to a range of intrinsic and extrinsic factors that functions to remove…”
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Alpha-Particle-Induced Complex Chromosome Exchanges Transmitted through Extra-Thymic Lymphopoiesis In Vitro Show Evidence of Emerging Genomic Instability by Sumption, Natalia, Goodhead, Dudley T, Anderson, Rhona M

“…Human exposure to high-linear energy transfer α-particles includes environmental (e.g. radon gas and its decay progeny), medical (e.g. radiopharmaceuticals)…”
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M-FISH Analysis Shows That Complex Chromosome Aberrations Induced by α-Particle Tracks Are Cumulative Products of Localized Rearrangements by Anderson, Rhona M., Stevens, David L., Goodhead, Dudley T.

“…Complex chromosome aberrations are characteristically induced after exposure to low doses of densely ionizing radiation, but little is understood about their…”
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DNA Damage Processing is Perturbed in Both Proliferative and Non-Proliferative Cells of Increased Chronological Cellular Age by Sabin, Rebecca, Pucci, Gaia, Anderson, Rhona M.

“…p53BP1 forms discrete foci within minutes of radiation exposure, at sites of DNA double-strand breaks, which ordinarily decay to background levels within 24 h…”
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The psychological consequences of (perceived) ionizing radiation exposure: a review on its role in radiation-induced cognitive dysfunction by Collett, George, Craenen, Kai, Young, William, Gilhooly, Mary, Anderson, Rhona M.

“…Exposure to ionizing radiation following environmental contamination (e.g., the Chernobyl and Fukushima nuclear accidents), radiotherapy and diagnostics,…”
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Exposure Worry: The Psychological Impact of Perceived Ionizing Radiation Exposure in British Nuclear Test Veterans by Collett, George, Young, William R., Martin, Wendy, Anderson, Rhona M.

“…Potential psychological issues faced by British nuclear test veterans have been under-researched. This study assessed the prevalence of clinically relevant…”
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Meeting report on ICRR2019, the 16th International Congress on Radiation Research by Williams, Kaye J, Hammond, Ester M, West, Catharine, Anderson, Rhona M, Badie, Christophe, Jeggo, Penny A

“…The 16th International Congress of Radiation Research (ICRR2019) was held in Manchester, UK, in August 2019. The Congress, which is held every four years,…”
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“Is that a coincidence?”: Exploring health perceptions and the causal attributions of physical health conditions in British nuclear test veterans by Collett, George, Martin, Wendy, Young, William R., Anderson, Rhona M.

“…Since the British nuclear testing programme, there have been several claims in the media and from the veterans themselves that their health (and descendants'…”
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Meeting report of the 16th international congress of radiation research and the 12th international symposium on chromosomal aberrations by Williams, Kaye, Jeggo, Penny A, Hammond, Ester M, West, Catharine, Badie, Christophe, Anderson, Rhona M

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Reduced chromosome aberration complexity in normal human bronchial epithelial cells exposed to low-LET γ-rays and high-LET α-particles by Themis, Matthew, Garimberti, Elisa, Hill, Mark A., Anderson, Rhona M.

“…Abstract Purpose: Cells of the lung are at risk from exposure to low and moderate doses of ionizing radiation from a range of environmental and medical…”
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Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells by Foster, Helen A., Estrada-Girona, Gemma, Themis, Matthew, Garimberti, Elisa, Hill, Mark A., Bridger, Joanna M., Anderson, Rhona M.

“…It is well established that chromosomes exist in discrete territories (CTs) in interphase and are positioned in a cell-type specific probabilistic manner. The…”
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Effect of Linear Energy Transfer (LET) on the Complexity of α-Particle-Induced Chromosome Aberrations in Human CD34+ Cells by Anderson, Rhona M., Stevens, David L., Sumption, Natalia D., Townsend, K. M Stuart, Goodhead, Dudley T., Hill, Mark A.

“…Anderson, R. M, Stevens, D. L., Sumption, N. D., Townsend, K. M. S., Goodhead, D. T. and Hill, M. A. Effect of Linear Energy Transfer (LET) on the Complexity…”
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Complex Chromosome Aberrations as Biomarkers of Exposure to High-LET Radiation: Plutonium-Worker Pilot Study by Anderson, Rhona M, Sevan'kaev, Aleksander V, Goodhead, Dudley T

“…A possible association between exposure to naturally occurring radon gas and its daughters and the development of myeloid leukemias and other cancers has been…”
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Transmissible and Nontransmissible Complex Chromosome Aberrations Characterized by Three-Color and mFISH Define a Biomarker of Exposure to High-LET α Particles by Anderson, Rhona M., Marsden, Samantha J., Paice, Stephen J., Bristow, Anna E., Kadhim, Munira A., Griffin, Carol S., Goodhead, Dudley T.

“…Anderson, R. M., Marsden, S. J., Paice, S. J., Bristow, A.;thE., Kadhim, M. A., Griffin, C. S. and Goodhead, D. T. Transmissible and Nontransmissible Complex…”
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mFISH Analysis Reveals Complexity of Chromosome Aberrations in Individuals Occupationally Exposed to Internal Plutonium: A Pilot Study to Assess the Relevance of Complex Aberrations as Biomarkers of Exposure to High-LET α Particles by Anderson, Rhona M., Tsepenko, Viktoria V., Gasteva, Galina N., Molokanov, Alexander A., Sevan'kaev, Aleksander V., Goodhead, Dudley T.

“…Anderson, R. M., Tsepenko, V. V., Gasteva, G. N., Molokanov, A. A., Sevan'kaev, A. V. and Goodhead, D. T. mFISH Analysis Reveals Complexity of Chromosome…”
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Alpha-Particle-Induced Complex Chromosome Exchanges Transmitted through Extra-Thymic Lymphopoiesis In Vitro Show Evidence of Emerging Genomic Instability: e0134046 by Sumption, Natalia, Goodhead, Dudley T, Anderson, Rhona M

“…Human exposure to high-linear energy transfer alpha -particles includes environmental (e.g. radon gas and its decay progeny), medical (e.g…”
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No increase in radiation-induced chromosome aberration complexity detected by m-FISH after culture in the presence of 5'-bromodeoxyuridine by Sumption, Natalia D, Goodhead, Dudley T, Anderson, Rhona M

“…The thymidine analogue, 5'-bromodeoxyuridine (BrdU), is a known mutagen that is routinely introduced into culture media for subsequent Harlequin stain analysis…”
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Meeting report on ICRR2019, the 16th International Congress on Radiation Research by Williams, Kaye J., Hammond, Ester M., West, Catharine, Anderson, Rhona M., Badie, Christophe, Jeggo, Penny A.

“…The 16th International Congress of Radiation Research (ICRR2019) was held in Manchester, UK, in August 2019. The Congress, which is held every four years,…”
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