Search Results - "Anderson, R.M."
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Myclobutanil enantioselective risk assessment in humans through in vitro CYP450 reactions: Metabolism and inhibition studies
Published in Food and chemical toxicology (01-06-2019)“…Myclobutanil is a chiral triazole fungicide that is employed worldwide. Although enantiomers have the same physical-chemical properties, they may differ in…”
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A comparison of two mathematical models of the impact of mass drug administration on the transmission and control of schistosomiasis
Published in Epidemics (01-03-2017)“…Highlights • This paper compares two mathematical models describing the transmission dynamics of schistosome infection and the impact of mass drug…”
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Neuroprotection by caloric restriction is associated with a distinct state of hippocampal energy metabolism linked to PGC-1alpha and GSK3beta
Published in Brain, behavior, and immunity (01-10-2015)“…The hippocampus is critical for cognition and memory formation and is vulnerable to age-related atrophy and loss of function. These phenotypes are attenuated…”
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Are patients with pulmonary tuberculosis who are identified through active case finding in the community different than those identified in healthcare facilities?
Published in New microbes and new infections (01-01-2017)“…Abstract The lack of healthcare access contributes to large numbers of tuberculosis (TB) cases being missed and has led to renewed interest in outreach…”
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Electron and hole mobility enhancement in strained SOI by wafer bonding
Published in IEEE transactions on electron devices (01-09-2002)“…N- and p-MOSFETs have been fabricated in strained Si-on-SiGe-on-insulator (SSOI) with high (15-25%) Ge content. Wafer bonding and H-induced layer transfer…”
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Adherence to antiretroviral therapy and its impact on clinical outcome in HIV-infected patients
Published in Journal of the Royal Society interface (22-09-2005)“…T-cell counts better than measures based on adherence data alone…”
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Cytogenetic Biomarkers of Radiation Exposure
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01-05-2019)“…Biological monitoring of radiation exposure relies heavily on the quantification of chromosome aberrations such as dicentrics and reciprocal translocations in…”
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Epidemic Thresholds and Vaccination in a Lattice Model of Disease Spread
Published in Theoretical population biology (01-10-1997)“…We use a lattice-based epidemic model to study the spatial and temporal rates of disease spread in a spatially distributed host population. The prevalence of…”
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Epidemiology and control of scrapie within a sheep flock
Published in Proceedings of the Royal Society. B, Biological sciences (07-07-1998)“…Mathematical models of the transmission dynamics of scrapie are used to explore the expected course of an outbreak in a sheep flock and the potential impacts…”
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Positive sexuality and its impact on overall well-being
Published in Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz (01-02-2013)“…Historically, the issue of sexual health has been largely considered with respect to the associated negative health outcomes. The dangers of sexual activity…”
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Dynamic transmission models and economic evaluations of pneumococcal conjugate vaccines: a quality appraisal and limitations
Published in Clinical microbiology and infection (01-01-2020)“…Of over 90 serotypes of Streptococcus pneumoniae, only seven were included in the first pneumococcal conjugate vaccine (PCV). While PCV reduced the disease…”
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Persistence and Dynamics in Lattice Models of Epidemic Spread
Published in Journal of theoretical biology (21-05-1996)“…We present a simple epidemic model representing the spread of a communicable disease in a spatially extended host population. The model falls into the general…”
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Feed-borne transmission and case clustering of BSE
Published in Proceedings of the Royal Society. B, Biological sciences (07-02-2000)“…An unresolved issue in the epidemiology of bovine spongiform encephalopathy (BSE) in the UK is what precisely determines the degree to which cases of disease…”
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Subtle changes in crosslinking drive diverse anomalous transport characteristics in actin-microtubule networks
Published in Soft matter (28-04-2021)“…Anomalous diffusion in crowded and complex environments is widely studied due to its importance in intracellular transport, fluid rheology and materials…”
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Combining hippocampal volume metrics to better understand Alzheimer’s disease progression in at-risk individuals
Published in Scientific reports (16-05-2019)“…To date nearly all clinical trials of Alzheimer’s disease (AD) therapies have failed. These failures are, at least in part, attributable to poor endpoint…”
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Both a 'magic bullet' and good aim are required to link public health interests and health care needs in HIV infection
Published in Nature medicine (01-03-2000)“…The incomplete distribution of HIV therapy, coupled with uneven HIV transmission rates throughout a population, seem to predict a failure of commodity health…”
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BSE in Northern Ireland: epidemiological patterns past, present and future
Published in Proceedings of the Royal Society. B, Biological sciences (07-04-1998)“…By 30 January 1998, there had been 170 259 confirmed cases of BSE in Great Britain (GB), 1766 confirmed cases in Northern Ireland (NI) (2 January 1998), and…”
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Biomimetic Metabolism of Kaurenoic Acid Validated by Microsomal Reactions
Published in Revista brasileira de farmacognosia (01-08-2020)“…The cytochrome P450 is a remarkable family of enzymes with widespread occurrence in animals and plants. In humans, they catalyze phase I metabolism reactions,…”
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Leishmanicidal Effects of Piperlongumine (Piplartine) and Its Putative Metabolites
Published in Planta medica (01-10-2018)“…Piperlongumine is an amide alkaloid found in Piperaceae species that shows a broad spectrum of biological properties, including antitumor and antiparasitic…”
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Metabolic profile and safety of piperlongumine
Published in Scientific reports (29-09-2016)“…Piperlongumine (PPL), a natural plant product, has been extensively studied in cancer treatment going up on clinical trials. Since the first report related to…”
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