Search Results - "Anderson, Paul J"
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The Role of RNA in Biological Phase Separations
Published in Journal of molecular biology (02-11-2018)“…Phase transitions that alter the physical state of ribonucleoprotein particles contribute to the spacial and temporal organization of the densely packed…”
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ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells
Published in Cell reports (Cambridge) (19-12-2017)“…Membraneless RNA granules originate via phase separation events driven by multivalent interactions. As RNA is the defining component of such granules, we…”
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Stress promotes RNA G-quadruplex folding in human cells
Published in Nature communications (13-01-2023)“…Guanine (G)-rich nucleic acids can fold into G-quadruplex (G4) structures under permissive conditions. Although many RNAs contain sequences that fold into RNA…”
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RNA biology of angiogenin: Current state and perspectives
Published in RNA biology (01-02-2017)“…Angiogenin (ANG) is a secreted ribonuclease best known for its ability to promote formation of blood vessels. Extensive research over many years has elucidated…”
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Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus
Published in Molecular cell (18-06-2020)“…Tumor interferon (IFN) signaling promotes PD-L1 expression to suppress T cell-mediated immunosurveillance. We identify the IFN-stimulated non-coding RNA 1…”
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Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma
Published in Science (American Association for the Advancement of Science) (25-03-2011)“…The precise transcriptional regulation of gene expression is essential for vertebrate development, but the role of posttranscriptional regulatory mechanisms is…”
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Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory
Published in Cell reports (Cambridge) (12-03-2019)“…TIA1 is a prion-related RNA-binding protein whose capacity to form various types of intracellular aggregates has been implicated in neurodegenerative disease…”
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Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases
Published in Frontiers in molecular biosciences (01-03-2022)“…Stress-induced tRNA cleavage has been implicated in various cellular processes, where tRNA fragments play diverse regulatory roles. Angiogenin (ANG), a member…”
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Acute Mountain Sickness Symptom Severity at the South Pole: The Influence of Self-Selected Prophylaxis with Acetazolamide
Published in PloS one (05-02-2016)“…Acetazolamide, a carbonic anhydrase inhibitor, remains the only FDA approved pharmaceutical prophylaxis for acute mountain sickness (AMS) though its…”
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Bisphenol A promotes stress granule assembly and modulates the integrated stress response
Published in Biology open (01-01-2021)“…Bisphenol-A (BPA) is a ubiquitous precursor of polycarbonate plastics that is found in the blood and serum of >92% of Americans. While BPA has been well…”
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Effect of exercise on anthropometric measures and serum lipids in older individuals: a systematic review and meta-analysis
Published in BMJ open (13-06-2014)“…Objectives Overweight and obesity are increasing in individuals over age 60 years. This systematic review quantifies the effect of exercise on body mass index…”
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Health status and health behaviors among citizen endurance Nordic skiers in the United States
Published in BMC research notes (24-07-2017)“…More than two-thirds of Americans are overweight or obese (69%) placing them at high risk for a wide array of chronic diseases. Physical activity anchors most…”
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YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression
Published in Nucleic acids research (19-08-2016)“…Stress-induced angiogenin (ANG)-mediated tRNA cleavage promotes a cascade of cellular events that starts with production of tRNA-derived stress-induced RNAs…”
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The State of Alaska's early experience with institutionalization of health impact assessment
Published in International journal of circumpolar health (01-01-2013)“…Background . Many nations routinely include health impact assessments (HIA) in public policy decisions. Institutionalization of HIA formally integrates health…”
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Tumor necrosis factor inhibitors: Clinical implications of their different immunogenicity profiles
Published in Seminars in arthritis and rheumatism (01-04-2005)“…The beneficial effects of the anti-tumor necrosis factor (TNF) monoclonal antibodies infliximab and adalimumab and the soluble receptor fusion protein…”
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TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation
Published in Molecular cancer research (01-08-2021)“…Tuberous sclerosis complex (TSC) is caused by mutations of either the or tumor suppressor gene. TSC causes tumors of the brain, heart, kidney, skin and…”
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Objective Versus Self-Reported Sleep Quality at High Altitude
Published in High altitude medicine & biology (01-06-2023)“…Anderson, Paul J., Christina M. Wood-Wentz, Kent R. Bailey, and Bruce D. Johnson. Objective versus self-reported sleep quality at high altitude. . 24:144-148,…”
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A tribute to Gerald Weissmann (1930-2019)
Published in The Journal of clinical investigation (01-11-2019)“…An obituary for Dr Gerald Weissmann, professor emeritus at New York University School of Medicine, ho died on Jul 10, 2019 is presented. Dr Weissmann was…”
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Using advanced racial and ethnic identity demographics to improve surveillance of work‐related conditions in an occupational clinic setting
Published in American journal of industrial medicine (01-05-2022)“…Background Although racial and ethnic identities are associated with a multitude of disparate medical outcomes, surveillance of these subpopulations in the…”
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Incidence and Symptoms of High Altitude Illness in South Pole Workers: Antarctic Study of Altitude Physiology (ASAP)
Published in Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine (01-01-2011)“…Introduction Each year, the US Antarctic Program rapidly transports scientists and support personnel from sea level (SL) to the South Pole (SP, 2835 m)…”
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