Search Results - "Anderson, James Melvin"

The N and C Termini of ZO-1 Are Surrounded by Distinct Proteins and Functional Protein Networks by Van Itallie, Christina M., Aponte, Angel, Tietgens, Amber Jean, Gucek, Marjan, Fredriksson, Karin, Anderson, James Melvin

“…The proteins and functional protein networks of the tight junction remain incompletely defined. Among the currently known proteins are barrier-forming proteins…”
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Claudin interactions in and out of the tight junction by Van Itallie, Christina M, Anderson, James Melvin

“…Claudins form the paracellular tight junction seal in epithelial tissues. Although there is still limited information on how these proteins are organized at…”
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Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability by Van Itallie, C, Rahner, C, Anderson, J M

“…Tight junctions regulate paracellular conductance and ionic selectivity. These properties vary among epithelia but the molecular basis of this variation…”
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The Molecular Physiology of Tight Junction Pores by Van Itallie, Christina M, Anderson, James Melvin

“…Christina M. Van Itallie 1 and James Melvin Anderson 2 1 Departments of Medicine and 2 Cell and Molecular Physiology, University of North Carolina at Chapel…”
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Claudins create charge-selective channels in the paracellular pathway between epithelial cells by Colegio, Oscar R, Van Itallie, Christina M, McCrea, Heather J, Rahner, Christoph, Anderson, James Melvin

“…Epithelia separate tissue spaces by regulating the passage of ions, solutes, and water through both the transcellular and paracellular pathways. Paracellular…”
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Setting up a selective barrier at the apical junction complex by Anderson, James Melvin, Van Itallie, Christina M, Fanning, Alan S

“…Across the animal kingdom the apical junction complex of epithelial cells creates both a permeability barrier and cell polarity. Although based on overlapping…”
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Isolation and functional characterization of the actin‐binding region in the tight junction protein ZO‐1 by Fanning, Alan S., Ma, Thomas Y., Anderson, James Melvin

“…Zonula occludens (ZO)‐1 is a member of the MAGUK (membrane‐associated guanylate kinase homologs) family of membrane‐associated signaling molecules that binds…”
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PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane by Fanning, A S, Anderson, J M

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The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton by Fanning, Alan S., Jameson, Brian J., Jesaitis, Lynne A., Anderson, James Melvin

“…The tight junction protein ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). ZO-1 has been…”
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Transmembrane proteins in the tight junction barrier by FANNING, A. S, MITIC, L. L, ANDERSON, J. M

“…Three types of transmembrane proteins have been identified within the tight junction, but it remains to be determined how they provide the molecular basis for…”
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Human CASK/LIN-2 Binds Syndecan-2 and Protein 4.1 and Localizes to the Basolateral Membrane of Epithelial Cells by Cohen, Alexandra R., Wood, Daniel F., Marfatia, Shirin M., Walther, Zenta, Chishti, Athar H., Anderson, James Melvin

“…In Caenorhabditis elegans, mutations in the lin-2 gene inactivate the LET-23 receptor tyrosine kinase/Ras/MAP kinase pathway required for vulval cell…”
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Expression, solubilization, and biochemical characterization of the tight junction transmembrane protein claudin‐4 by Mitic, Laura L., Unger, Vinzenz M., Anderson, James Melvin

“…The tight junction tetraspan protein claudin‐4 creates a charge‐selective pore in the paracellular pathway across epithelia. The structure of the pore is…”
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Occludin confers adhesiveness when expressed in fibroblasts by Van Itallie, C M, Anderson, J M

“…Occludin is an integral membrane protein specifically associated with tight junctions. Previous studies suggest it is likely to function in forming the…”
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The structure and regulation of tight junctions by Anderson, J M, Balda, M S, Fanning, A S

“…Tight junctions create a paracellular barrier between both epithelial and endothelial cells. Recent advances have helped define their molecular composition and…”
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Connexin-Occludin Chimeras Containing the ZO-Binding Domain of Occludin Localize at MDCK Tight Junctions and NRK Cell Contacts by Mitic, Laura L., Schneeberger, Eveline E., Fanning, Alan S., Anderson, James Melvin

“…Occludin is a transmembrane protein of the tight junction that functions in creating both an intercellular permeability barrier and an intramembrane diffusion…”
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Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells by Van Itallie, C M, Balda, M S, Anderson, J M

“…Addition of epidermal growth factor (EGF) to A431 human epidermal carcinoma cells results in actin reorganization and phosphorylation of several cytoskeletal…”
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Newly synthesized claudins but not occludin are added to the basal side of the tight junction by Van Itallie, Christina M, Lidman, Karin Fredriksson, Tietgens, Amber Jean, Anderson, James Melvin

“…A network of claudin strands creates continuous cell-cell contacts to form the intercellular tight junction barrier; a second protein, occludin, is associated…”
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Molecular Structure of Tight Junctions and Their Role in Epithelial Transport by Anderson, James Melvin

“…James Melvin Anderson J. M. Anderson is a Professor of Medicine and Cell Biology at the Yale School of Medicine, New Haven, Connecticut 06520-8019. Tight…”
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The Life and Work of Shoichiro Tsukita by Anderson, James Melvin

“…We dedicate the 2008 Berlin conference and this collection of scientific manuscripts to the memory of our colleague Shoichiro Tsukita. His seminal scientific…”
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Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture by Colegio, Oscar R, Van Itallie, Christina, Rahner, Christoph, Anderson, James Melvin

“…Tight junctions (TJs) regulate paracellular permeability across epithelia and vary widely in their transepithelial electrical resistance (TER) and charge…”
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