Search Results - "Anderson, J. C"

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study by Phyo, Aung Pyae, MD, Nkhoma, Standwell, PhD, Stepniewska, Kasia, PhD, Ashley, Elizabeth A, MD, Nair, Shalini, MSc, McGready, Rose, MD, ler Moo, Carit, Al-Saai, Salma, MSc, Dondorp, Arjen M, MD, Lwin, Khin Maung, MD, Singhasivanon, Pratap, MD, Day, Nicholas PJ, FRCP, White, Nicholas J, FRS, Anderson, Tim JC, PhD, Nosten, François, Prof

“…Summary Background Artemisinin-resistant falciparum malaria has arisen in western Cambodia. A concerted international effort is underway to contain…”
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A Major Genome Region Underlying Artemisinin Resistance in Malaria by Cheeseman, Ian H., Miller, Becky A., Nair, Shalini, Nkhoma, Standwell, Tan, Asako, Tan, John C., Saai, Salma Al, Phyo, Aung Pyae, Moo, Carit Ler, Lwin, Khin Maung, McGready, Rose, Ashley, Elizabeth, Imwong, Mallika, Stepniewska, Kasia, Yi, Poravuth, Dondorp, Arjen M., Mayxay, Mayfong, Newton, Paul N., White, Nicholas J., Nosten, François, Ferdig, Michael T., Anderson, Timothy J. C.

“…Evolving resistance to arte misi ni n-based compounds threatens to derail attempts to control malaria. Resistance has been confirmed in western Cambodia and…”
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Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance by Cerqueira, Gustavo C, Cheeseman, Ian H, Schaffner, Steve F, Nair, Shalini, McDew-White, Marina, Phyo, Aung Pyae, Ashley, Elizabeth A, Melnikov, Alexandre, Rogov, Peter, Birren, Bruce W, Nosten, François, Anderson, Timothy J C, Neafsey, Daniel E

“…Artemisinin-based combination therapies are the first line of treatment for Plasmodium falciparum infections worldwide, but artemisinin resistance has risen…”
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Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent by Taylor, Aimee R, Schaffner, Stephen F, Cerqueira, Gustavo C, Nkhoma, Standwell C, Anderson, Timothy J C, Sriprawat, Kanlaya, Pyae Phyo, Aung, Nosten, François, Neafsey, Daniel E, Buckee, Caroline O

“…With the rapidly increasing abundance and accessibility of genomic data, there is a growing interest in using population genetic approaches to characterize…”
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Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species by Pearce, S L, Clarke, D F, East, P D, Elfekih, S, Gordon, K H J, Jermiin, L S, McGaughran, A, Oakeshott, J G, Papanicolaou, A, Perera, O P, Rane, R V, Richards, S, Tay, W T, Walsh, T K, Anderson, A, Anderson, C J, Asgari, S, Board, P G, Bretschneider, A, Campbell, P M, Chertemps, T, Christeller, J T, Coppin, C W, Downes, S J, Duan, G, Farnsworth, C A, Good, R T, Han, L B, Han, Y C, Hatje, K, Horne, I, Huang, Y P, Hughes, D S T, Jacquin-Joly, E, James, W, Jhangiani, S, Kollmar, M, Kuwar, S S, Li, S, Liu, N-Y, Maibeche, M T, Miller, J R, Montagne, N, Perry, T, Qu, J, Song, S V, Sutton, G G, Vogel, H, Walenz, B P, Xu, W, Zhang, H-J, Zou, Z, Batterham, P, Edwards, O R, Feyereisen, R, Gibbs, R A, Heckel, D G, McGrath, A, Robin, C, Scherer, S E, Worley, K C, Wu, Y D

“…Helicoverpa armigera and Helicoverpa zea are major caterpillar pests of Old and New World agriculture, respectively. Both, particularly H. armigera, are…”
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A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni by Protasio, Anna V, Tsai, Isheng J, Babbage, Anne, Nichol, Sarah, Hunt, Martin, Aslett, Martin A, De Silva, Nishadi, Velarde, Giles S, Anderson, Tim J C, Clark, Richard C, Davidson, Claire, Dillon, Gary P, Holroyd, Nancy E, LoVerde, Philip T, Lloyd, Christine, McQuillan, Jacquelline, Oliveira, Guilherme, Otto, Thomas D, Parker-Manuel, Sophia J, Quail, Michael A, Wilson, R Alan, Zerlotini, Adhemar, Dunne, David W, Berriman, Matthew

“…Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people in developing countries. Amongst the human-infective species,…”
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Erasing the Milky Way: new cleaning technique applied to GBT intensity mapping data by Wolz, L, Blake, C, Abdalla, F B, Anderson, C J, Chang, T-C, Li, Y -C, Masui, K W, Switzer, E, Pen, U-L, Voytek, T C, Yadav, J

“…We present the first application of a new foreground removal pipeline to the current leading H i intensity mapping data set, obtained by the Green Bank…”
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Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study by Amaratunga, Chanaki, PhD, Sreng, Sokunthea, Suon, Seila, MD, Phelps, Erika S, BA, Stepniewska, Kasia, PhD, Lim, Pharath, MD, Zhou, Chongjun, MD, Mao, Sivanna, MD, Anderson, Jennifer M, PhD, Lindegardh, Niklas, PhD, Jiang, Hongying, PhD, Song, Jianping, Prof, Su, Xin-zhuan, PhD, White, Nicholas J, Prof, Dondorp, Arjen M, Prof, Anderson, Tim JC, Prof, Fay, Michael P, PhD, Mu, Jianbing, MD, Duong, Socheat, Prof, Fairhurst, Rick M, Dr

“…Summary Background Artemisinin-resistant Plasmodium falciparum has been reported in Pailin, western Cambodia, detected as a slow parasite clearance rate in…”
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Population genetic correlates of declining transmission in a human pathogen by Nkhoma, Standwell C., Nair, Shalini, Al-Saai, Salma, Ashley, Elizabeth, McGready, Rose, Phyo, Aung P., Nosten, François, Anderson, Tim J. C.

“…Pathogen control programs provide a valuable, but rarely exploited, opportunity to directly examine the relationship between population decline and population…”
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Non-Lethal Blood Sampling of Fish in the lab and Field With Methods for Dried Blood Plasma Spot Omic Analyses by Pollard, S, Anderson, J C, Bah, F, Mateus, M, Sidhu, M, Simmons, Dbd

“…There is global acknowledgment that humane methods in animal research are a priority, but few environmental effects monitoring programs use nonlethal methods…”
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Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites by Valentim, Claudia L. L., Cioli, Donato, Chevalier, Frédéric D., Cao, Xiaohang, Taylor, Alexander B., Holloway, Stephen P., Pica-Mattoccia, Livia, Guidi, Alessandra, Basso, Annalisa, Tsai, Isheng J., Berriman, Matthew, Carvalho-Queiroz, Claudia, Almeida, Marcio, Aguilar, Hector, Frantz, Doug E., Hart, P. John, LoVerde, Philip T., Anderson, Timothy J. C.

“…Oxamniquine resistance evolved in the human blood fluke (Schistosoma monsoni) in Brazil in the 1970s. We crossed parental parasites differing -500-fold in drug…”
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Identity-by-descent with uncertainty characterises connectivity of Plasmodium falciparum populations on the Colombian-Pacific coast by Taylor, Aimee R, Echeverry, Diego F, Anderson, Timothy J C, Neafsey, Daniel E, Buckee, Caroline O

“…Characterising connectivity between geographically separated biological populations is a common goal in many fields. Recent approaches to understanding…”
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Neuroimaging Features of Neurodegeneration with Brain Iron Accumulation by KRUER, M. C, BODDAERT, N, SCHNEIDER, S. A, HOULDEN, H, BHATIA, K. P, GREGORY, A, ANDERSON, J. C, ROONEY, W. D, HOGARTH, P, HAYFLICK, S. J

“…NBIA characterizes a class of neurodegenerative diseases that feature a prominent extrapyramidal movement disorder, intellectual deterioration, and a…”
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Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle by Li, Xue, Kumar, Sudhir, McDew-White, Marina, Haile, Meseret, Cheeseman, Ian H, Emrich, Scott, Button-Simons, Katie, Nosten, François, Kappe, Stefan H I, Ferdig, Michael T, Anderson, Tim J C, Vaughan, Ashley M

“…Determining the genetic basis of fitness is central to understanding evolution and transmission of microbial pathogens. In human malaria parasites (Plasmodium…”
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Molecular and Pharmacological Determinants of the Therapeutic Response to Artemether-Lumefantrine in Multidrug-Resistant Plasmodium falciparum Malaria by Price, Ric N., Uhlemann, Anne-Catrin, van Vugt, Michele, Brockman, Al, Hutagalung, Robert, Nair, Shalini, Nash, Denae, Singhasivanon, Pratap, Anderson, Tim J. C., Krishna, Sanjeev, White, Nicholas J., Nosten, François

“…Background. Our study examined the relative contributions of host, pharmacokinetic, and parasitological factors in determining the therapeutic response to…”
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Contribution of parasite and host genotype to immunopathology of schistosome infections by Jutzeler, Kathrin S, Le Clec'h, Winka, Chevalier, Frédéric D, Anderson, Timothy J C

“…The role of pathogen genotype in determining disease severity and immunopathology has been studied intensively in microbial pathogens including bacteria,…”
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Resolving drug selection and migration in an inbred South American Plasmodium falciparum population with identity-by-descent analysis by Carrasquilla, Manuela, Early, Angela M, Taylor, Aimee R, Knudson Ospina, Angélica, Echeverry, Diego F, Anderson, Timothy J C, Mancilla, Elvira, Aponte, Samanda, Cárdenas, Pablo, Buckee, Caroline O, Rayner, Julian C, Sáenz, Fabián E, Neafsey, Daniel E, Corredor, Vladimir

“…The human malaria parasite Plasmodium falciparum is globally widespread, but its prevalence varies significantly between and even within countries. Most…”
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Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment by Chevalier, Frédéric D, Le Clec'h, Winka, McDew-White, Marina, Menon, Vinay, Guzman, Meghan A, Holloway, Stephen P, Cao, Xiaohang, Taylor, Alexander B, Kinung'hi, Safari, Gouvras, Anouk N, Webster, Bonnie L, Webster, Joanne P, Emery, Aidan M, Rollinson, David, Garba Djirmay, Amadou, Al Mashikhi, Khalid M, Al Yafae, Salem, Idris, Mohamed A, Moné, Hélène, Mouahid, Gabriel, Hart, P John, LoVerde, Philip T, Anderson, Timothy J C

“…Do mutations required for adaptation occur de novo, or are they segregating within populations as standing genetic variation? This question is key to…”
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High Heritability of Malaria Parasite Clearance Rate Indicates a Genetic Basis for Artemisinin Resistance in Western Cambodia by Anderson, Tim J. C., Nair, Shalini, Nkhoma, Standwell, Williams, Jeff T., Imwong, Mallika, Yi, Poravuth, Socheat, Duong, Das, Debashish, Chotivanich, Kesinee, Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M.

“…In western Cambodia, malaria parasites clear slowly from the blood after treatment with artemisinin derivatives, but it is unclear whether this results from…”
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No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host by Le Clec'h, Winka, Chevalier, Frédéric D, Jutzeler, Kathrin, Anderson, Timothy J C

“…The trematode parasite Schistosoma mansoni uses an aquatic snail intermediate and a vertebrate definitive host to complete its life cycle. We previously showed…”
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