Search Results - "Anderson, Amy E."

What are the dominant cytokines in early rheumatoid arthritis? by Ridgley, Laura A, Anderson, Amy E, Pratt, Arthur G

“…PURPOSE OF REVIEWRheumatoid arthritis is a systemic disease of evolving immune dysregulation that culminates in joint destruction and disability. The principle…”
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Intimate partner violence adversely impacts health over 16 years and across generations: A longitudinal cohort study by Loxton, Deborah, Dolja-Gore, Xenia, Anderson, Amy E, Townsend, Natalie

“…To determine the impact of intimate partner violence on women's mental and physical health over a 16 year period and across three generations. Participants…”
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Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission by Baker, Kenneth F., McDonald, David, Hulme, Gillian, Hussain, Rafiqul, Coxhead, Jonathan, Swan, David, Schulz, Axel R., Mei, Henrik E., MacDonald, Lucy, Pratt, Arthur G., Filby, Andrew, Anderson, Amy E., Isaacs, John D.

“…Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of…”
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Immune-related adverse events in checkpoint blockade: Observations from human tissue and therapeutic considerations by Williams, Kristian C, Gault, Abigail, Anderson, Amy E, Stewart, Christopher J, Lamb, Christopher A, Speight, R Ally, Rajan, Neil, Plummer, Ruth, Pratt, Arthur G

“…Checkpoint inhibitors (CPIs) are monoclonal antibodies which, by disrupting interactions of immune checkpoint molecules with their ligands, block regulatory…”
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Autologous Protein Solution processing alters lymphoid and myeloid cell populations and modulates gene expression dependent on cell type by Peña, Alexis N, Sommerfeld, Sven D, Anderson, Amy E, Han, Jin, Maestas, Jr, David R, Mejias, Joscelyn C, Woodell-May, Jennifer, King, William, Ganguly, Sudipto, Elisseeff, Jennifer H

“…Osteoarthritis (OA) is a degenerative disease associated with cartilage degradation, osteophyte formation, and fibrillation. Autologous Protein Solution (APS),…”
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Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study by Gault, Abigail, Hogarth, Linda, Williams, Kristian C, Greystoke, Alastair, Rajan, Neil, Speight, Ally, Lamb, Christopher A, Bridgewood, Alison, Brown-Schofield, Lisa-Jayne, Rayner, Fiona, Isaacs, John D, Nsengimana, Jérémie, Stewart, Christopher J, Anderson, Amy E, Plummer, Ruth, Pratt, Arthur G

“…Checkpoint inhibitors (CPIs) are widely used in cancer treatment, with transformative impacts on survival. They nonetheless carry a significant risk of…”
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Alcohol‐related risk from pre‐loading and heavy episodic drinking (HED) among a cohort of young Australian women: a cross‐sectional analysis by Anderson, Amy E., Cavenagh, Dominic, Forder, Peta, Loxton, Deborah, Byles, Julie

“…To cross‐sectionally examine heavy episodic drinking (HED) and pre‐loading with alcohol among young Australian women in relation to the alcohol‐induced adverse…”
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Antenatal care for alcohol consumption during pregnancy: pregnant women's reported receipt of care and associated characteristics by Doherty, Emma, Wiggers, John, Wolfenden, Luke, Anderson, Amy E, Crooks, Kristy, Tsang, Tracey W, Elliott, Elizabeth J, Dunlop, Adrian J, Attia, John, Dray, Julia, Tully, Belinda, Bennett, Nicole, Murray, Henry, Azzopardi, Carol, Kingsland, Melanie

“…Antenatal clinical guidelines recommend that during initial and subsequent antenatal visits all pregnant women: have their alcohol consumption assessed; be…”
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Association between preconception maternal stress and offspring birth weight: findings from an Australian longitudinal data linkage study by Harris, Melissa L, Hure, Alexis J, Holliday, Elizabeth, Chojenta, Catherine, Anderson, Amy E, Loxton, Deborah

“…ObjectiveExamine the relationship between preconception stress and offspring birth weight.SettingPopulation-based cohort study linked with state-based…”
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LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells by Anderson, Amy E., Swan, David J., Sayers, Bethan L., Harry, Rachel A., Patterson, Angela M., Delwig, Alexei, Robinson, John H., Isaacs, John D., Hilkens, Catharien M. U.

“…Autoimmune pathologies are caused by a breakdown in self‐tolerance. Tolerogenic dendritic cells (tolDC) are a promising immunotherapeutic tool for restoring…”
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Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis by Spiering, Rachel, Jansen, Manon A A, Wood, Matthew J, Fath, Anshorulloh A, Eltherington, Oliver, Anderson, Amy E, Pratt, Arthur G, van Eden, Willem, Isaacs, John D, Broere, Femke, Hilkens, Catharien M U

“…Autologous tolerogenic dendritic cells (tolDC) are a promising therapeutic strategy for inflammatory arthritis (IA) as they can regulate autoantigen-specific T…”
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Metabolically Active Three-Dimensional Brown Adipose Tissue Engineered from White Adipose-Derived Stem Cells by Yang, Jessica P, Anderson, Amy E, McCartney, Annemarie, Ory, Xavier, Ma, Garret, Pappalardo, Elisa, Bader, Joel, Elisseeff, Jennifer H

“…Brown adipose tissue (BAT) has a unique capacity to expend calories by decoupling energy expenditure from ATP production, therefore BAT could realize…”
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Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis by Cooles, Faye A H, Anderson, Amy E, Skelton, Andrew, Pratt, Arthur G, Kurowska-Stolarska, Mariola S, McInnes, Iain, Hilkens, Catharien M U, Isaacs, John D

“…Dendritic cells (DCs) are key orchestrators of immune function. To date, rheumatoid arthritis (RA) researchers have predominantly focused on a potential…”
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A negative feedback loop mediated by STAT3 limits human Th17 responses by Purvis, Harriet A, Anderson, Amy E, Young, David A, Isaacs, John D, Hilkens, Catharien M U

“…The transcription factor STAT3 is critically required for the differentiation of Th17 cells, a T cell subset involved in various chronic inflammatory diseases…”
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IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function by Ridgley, Laura A, Anderson, Amy E, Maney, Nicola J, Naamane, Najib, Skelton, Andrew J, Lawson, Catherine A, Emery, Paul, Isaacs, John D, Carmody, Ruaidhrí J, Pratt, Arthur G

“…We have previously shown that increased circulating interleukin-6 (IL-6) results in enhanced CD4+ T cell signaling via signal transduction and activator of…”
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Fluorine labelling of therapeutic human tolerogenic dendritic cells for 19F-magnetic resonance imaging by Cooke, Fiona, Neal, Mary, Wood, Matthew J., de Vries, I. Jolanda M., Anderson, Amy E., Diboll, Julie, Pratt, Arthur G., Stanway, James, Nicorescu, Ioana, Moyse, Nicholas, Hiles, Dawn, Caulfield, David, Dickinson, Anne M., Blamire, Andrew M., Thelwall, Pete, Isaacs, John D., Hilkens, Catharien M. U.

“…Tolerogenic dendritic cell (tolDC) therapies aim to restore self-tolerance in patients suffering from autoimmune diseases. Phase 1 clinical trials with tolDC…”
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A practice change intervention to improve antenatal care addressing alcohol consumption by women during pregnancy: research protocol for a randomised stepped-wedge cluster trial by Kingsland, Melanie, Doherty, Emma, Anderson, Amy E, Crooks, Kristy, Tully, Belinda, Tremain, Danika, Tsang, Tracey W, Attia, John, Wolfenden, Luke, Dunlop, Adrian J, Bennett, Nicole, Hunter, Mandy, Ward, Sarah, Reeves, Penny, Symonds, Ian, Rissel, Chris, Azzopardi, Carol, Searles, Andrew, Gillham, Karen, Elliott, Elizabeth J, Wiggers, John

“…Despite clinical guideline recommendations, implementation of antenatal care addressing alcohol consumption by pregnant women is limited. Implementation…”
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An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial by Anderson, Amy E., Wu, Iwen, Parrillo, Alexis J., Wolf, Matthew T., Maestas, David R., Graham, Ian, Tam, Ada J., Payne, Rachael M., Aston, Jeffrey, Cooney, Carisa M., Byrne, Patrick, Cooney, Damon S., Elisseeff, Jennifer H.

“…Soft tissue reconstruction remains an intractable clinical challenge as current surgical options and synthetic implants may produce inadequate outcomes. Soft…”
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Barriers to the implementation of clinical guidelines for maternal alcohol consumption in antenatal services: A survey using the theoretical domains framework by Doherty, Emma, Kingsland, Melanie, Wiggers, John, Anderson, Amy E., Elliott, Elizabeth J., Symonds, Ian, Tully, Belinda, Dray, Julia, Wolfenden, Luke

“…Issue addressed: The aim of this study was to assess potential barriers to the implementation of clinical guideline recommendations regarding maternal alcohol…”
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Adenosine metabolic signature in circulating CD4+ T cells predicts remission in rheumatoid arthritis by Brown, Philip M, Anderson, Amy E, Naamane, Najib, Lendrem, Dennis W, Morgan, Ann W, Isaacs, John D, Pratt, Arthur G

“…ObjectivesLong-term outcomes in rheumatoid arthritis (RA) depend on early and effective disease control. Methotrexate (MTX) remains the first-line disease…”
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