Search Results - "Anderson, A.R.A."
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Mathematical modeling of tumor-induced angiogenesis
Published in Annual review of biomedical engineering (01-01-2006)“…Angiogenesis, the growth of a network of blood vessels, is a crucial component of solid tumor growth, linking the relatively harmless avascular and the…”
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SP-0013: A mathematical model of tumor self-seeding reveals secondary metastatic deposits as drivers of primary tumor growth
Published in Radiotherapy and oncology (01-03-2013)Get full text
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A mathematical model for capillary network formation in the absence of endothelial cell proliferation
Published in Applied mathematics letters (01-05-1998)“…A mathematical model for endothelial cell migration during tumour-induced angiogenesis is presented. A possible explanation, in terms of desensitisation of…”
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Does breast cancer exist in a state of chaos?
Published in European journal of cancer (1990) (01-06-1999)Get full text
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Treatment of evolving cancers will require dynamic decision support
Published in Annals of oncology (01-10-2023)“…Cancer research has traditionally focused on developing new agents, but an underexplored question is that of the dose and frequency of existing drugs. Based on…”
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An evolutionary hybrid cellular automaton model of solid tumour growth
Published in Journal of theoretical biology (21-06-2007)“…We propose a cellular automaton model of solid tumour growth, in which each cell is equipped with a micro-environment response network. This network is…”
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A hybrid cellular automaton model of clonal evolution in cancer: The emergence of the glycolytic phenotype
Published in Journal of theoretical biology (21-02-2008)“…We present a cellular automaton model of clonal evolution in cancer aimed at investigating the emergence of the glycolytic phenotype. In the model each cell is…”
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Evolution of cell motility in an individual-based model of tumour growth
Published in Journal of theoretical biology (07-07-2009)“…Tumour invasion is driven by proliferation and importantly migration into the surrounding tissue. Cancer cell motility is also critical in the formation of…”
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Mathematical modelling of flow in 2D and 3D vascular networks: Applications to anti-angiogenic and chemotherapeutic drug strategies
Published in Mathematical and computer modelling (01-05-2005)“…The aim of this paper is to investigate the conditions required to optimize the amount of chemotherapeutic drug absorbed by a solid tumour through a network of…”
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Mathematical modelling of the influence of blood rheological properties upon adaptative tumour-induced angiogenesis
Published in Mathematical and computer modelling (01-07-2006)“…In this paper, we present a theoretical investigation of the influence of blood flow through a tumour-induced capillary network, whereby the vascular…”
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Continuous and Discrete Mathematical Models of Tumor-induced Angiogenesis
Published in Bulletin of mathematical biology (01-09-1998)“…Angiogenesis, the formation of blood vessels from a pre-existing vasculature, is a process whereby capillary sprouts are formed in response to externally…”
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Mathematical Modelling of Flow Through Vascular Networks: Implications for Tumour-induced Angiogenesis and Chemotherapy Strategies
Published in Bulletin of mathematical biology (01-07-2002)“…Angiogenesis, the formation of blood vessels from a pre-existing vasculature, is a process whereby capillary sprouts are formed in response to externally…”
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Modelling evolutionary cell behaviour using neural networks: Application to tumour growth
Published in BioSystems (01-02-2009)“…In this paper, we present a modelling framework for cellular evolution that is based on the notion that a cell’s behaviour is driven by interactions with other…”
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Perspectives on tissue interactions in development and disease
Published in Current molecular medicine (01-02-2010)“…From the morphogenetic movements of the three germ layers during development to the reactive stromal microenvironment in cancer, tissue interactions are vital…”
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Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices
Published in Lab on a chip (01-01-2008)“…Historically, it has been difficult to generate accurate and reproducible protein gradients for studies of interactions between cells and extracellular matrix…”
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Gene divergence and pathway duplication in the metabolic network of yeast and digital organisms
Published in Journal of the Royal Society interface (06-12-2009)“…revealed precisely this; genes involved in many pathways are more likely to increase their connectivity. Measuring the overlap between different pathways, in…”
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Immune interconnectivity of anatomically distant tumors as a potential mediator of systemic responses to local therapy
Published in Scientific reports (21-06-2018)“…Complex interactions occur between tumor and host immune system at each site in the metastatic setting, the outcome of which can determine behavior ranging…”
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A gradient-driven mathematical model of antiangiogenesis
Published in Mathematical and computer modelling (01-11-2000)“…In this paper, we present a mathematical model describing the angiogenic response of endothelial cells to a secondary tumour. It has been observed…”
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A mathematical analysis of a model for capillary network formation in the absence of endothelial cell proliferation
Published in Applied mathematics letters (01-11-1999)“…An analysis of a parabolic partial differential equation modelling capillary network formation is presented. The model includes terms representing cell random…”
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Steady-state solutions of a generic model for the formation of capillary networks
Published in Applied mathematics letters (01-07-2000)“…A steady-state analysis of solutions of a generic model for capillary network formation is discussed. Under certain circumstances such solutions represent…”
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