Search Results - "Andersohn, Alexander"
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Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke
Published in Journal of neuroinflammation (07-10-2023)“…Stroke is the most common cause of long-term disability and places a high economic burden on the global healthcare system. Functional outcomes from stroke are…”
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Aggregated and Hyperstable Damage-Associated Molecular Patterns Are Released During ER Stress to Modulate Immune Function
Published in Frontiers in cell and developmental biology (18-09-2019)“…Chronic ER stress occurs when protein misfolding in the Endoplasmic reticulum (ER) lumen remains unresolved despite activation of the unfolded protein…”
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Abstract TMP111: Selective Activation of Peritoneal TRPV1-Containing Vagal Afferents Promotes Sustained Mild Hypothermia and Neuroprotection Following Stroke
Published in Stroke (1970) (01-02-2024)“…Abstract only Intro: Mild hypothermia has been clinically effective at improving outcomes in cardiac arrest patients for decades. Similarly, mild hypothermia…”
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Abstract WP216: Intraperitoneal Delivery Of Capsinoids (Non-pungent TRPV1 Agonists) Promotes Mild Hypothermia And Improved Long-term Outcome Following Stroke
Published in Stroke (1970) (01-02-2023)“…IntroMild hypothermia has been shown to improve outcomes in cardiac arrest and experimental stroke models. Unfortunately, hypothermia protocols in awake…”
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Abstract TMP112: Von Willebrand Factor (VWF) Modulates Smooth Muscle Cell Proliferation During the Outward Remodeling of Leptomeningeal Collateral Arterioles Following Stroke
Published in Stroke (1970) (01-02-2024)“…Abstract only Introduction: The leptomeningeal collaterals (LMCs) undergo outward remodeling after stroke to increase rescue flow toward the occluded region…”
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Abstract WP232: Endothelial Knockout Of Piezo1 Results In Reduced Cerebral Blood Flow, Brain Gliosis, And Functional Changes In Gait
Published in Stroke (1970) (01-02-2023)“…IntroductionPiezo1 is a calcium-permeable mechanosensitive ion channel that is opened by membrane stretch or increased shear force. In peripheral vasculature,…”
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Abstract WMP116: Ifi27l2a Is A Novel Regulator Of Neuroinflammation And Neurodegeneration In The Post-stroke Brain
Published in Stroke (1970) (01-02-2023)“…Microglial cells (MG) serve as resident immune cells in the brain and play a critical role in the acute response and chronic recovery to stroke. We compared…”
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Abstract WP300: Ifi27l2a is a Novel Target for Dampening Microglial Inflammation Following Stroke
Published in Stroke (1970) (01-02-2024)“…Abstract only Microglia play a critical role in initiating and spreading inflammation and are involved in the chronic recovery phase following stroke…”
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Abstract 42: Von Willebrand Factor (vwf) Is Required For Outward Remodeling Of Leptomeningeal Collateral Arterioles Following Stroke
Published in Stroke (1970) (01-02-2023)“…IntroductionVWF is an endothelial glycoprotein with known roles in vascular hemostasis and thrombosis. We previously showed increased expression of VWF in…”
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Abstract WP221: Rnaseq Reveals An Angiogenic Signature Of Leptomeningeal Collaterals In Pig Brain
Published in Stroke (1970) (01-02-2023)“…IntroductionThe leptomeningeal collaterals (LMCs) are specialized brain surface arterioles that interconnect the distalmost arterioles (DMAs) of the major…”
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Abstract WP247: Two Novel Interferon Signaling Proteins (Ifi27l2a And Ifitm3) Regulate Microglial Inflammation With Brain Aging And Following Stroke
Published in Stroke (1970) (01-02-2022)“…Interferon signaling drives neuroinflammation in AD and stroke. Microglia (MG) play a critical role in initiating and spreading inflammation and are involved…”
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Chronic ER Stress Leads to Hepatic Damp Production
Published in Biophysical journal (15-02-2019)Get full text
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