Search Results - "Andersen, Jens Peter"
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Global citation inequality is on the rise
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2021)“…Citations are important building blocks for status and success in science. We used a linked dataset of more than 4 million authors and 26 million scientific…”
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A Combined Zinc/Cadmium Sensor and Zinc/Cadmium Export Regulator in a Heavy Metal Pump
Published in The Journal of biological chemistry (08-10-2010)“…Heavy metal pumps (P1B-ATPases) are important for cellular heavy metal homeostasis. AtHMA4, an Arabidopsis thaliana heavy metal pump of importance for plant…”
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3
Lack of consideration of sex and gender in COVID-19 clinical studies
Published in Nature communications (06-07-2021)“…Sex and gender differences impact the incidence of SARS-CoV-2 infection and COVID-19 mortality. Furthermore, sex differences influence the frequency and…”
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COVID-19 medical papers have fewer women first authors than expected
Published in eLife (15-06-2020)“…The COVID-19 pandemic has resulted in school closures and distancing requirements that have disrupted both work and family life for many. Concerns exist that…”
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Gender variations in citation distributions in medicine are very small and due to self-citation and journal prestige
Published in eLife (15-07-2019)“…A number of studies suggest that scientific papers with women in leading-author positions attract fewer citations than those with men in leading-author…”
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Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2012)“…ATP8A2 is a P4-ATPase ("flippase") located in membranes of retinal photoreceptors, brain cells, and testis, where it mediates transport of aminophospholipids…”
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Functional and in silico analysis of ATP8A2 and other P4-ATPase variants associated with human genetic diseases
Published in Disease models & mechanisms (01-06-2024)“…P4-ATPases flip lipids from the exoplasmic to cytoplasmic leaflet of cell membranes, a property crucial for many biological processes. Mutations in P4-ATPases…”
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Author-level data confirm the widening gender gap in publishing rates during COVID-19
Published in eLife (16-03-2022)“…Publications are essential for a successful academic career, and there is evidence that the COVID-19 pandemic has amplified existing gender disparities in the…”
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A structural overview of the plasma membrane Na + ,K + -ATPase and H + -ATPase ion pumps
Published in Nature reviews. Molecular cell biology (01-01-2011)“…Key Points Ions are transported across the plasma membrane by molecular pumps to generate chemical gradients and regulate pH or cell growth. P-type ATPases are…”
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10
Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P 4 -ATPase ATP8A2
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2012)“…ATP8A2 is a P 4 -ATPase (“flippase”) located in membranes of retinal photoreceptors, brain cells, and testis, where it mediates transport of aminophospholipids…”
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11
Crystal Structure of the Vanadate-Inhibited Ca2+-ATPase
Published in Structure (London) (05-04-2016)“…Vanadate is the hallmark inhibitor of the P-type ATPase family; however, structural details of its inhibitory mechanism have remained unresolved. We have…”
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12
Is something rotten in the state of Denmark? Cross-national evidence for widespread involvement but not systematic use of questionable research practices across all fields of research
Published in PloS one (12-08-2024)“…Questionable research practices (QRP) are believed to be widespread, but empirical assessments are generally restricted to a few types of practices…”
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13
Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic
Published in Proceedings of the National Academy of Sciences - PNAS (13-08-2019)“…Phospholipid flippases (P4-ATPases) utilize ATP to translocate specific phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of biological…”
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14
Dynamics of P-type ATPase transport revealed by single-molecule FRET
Published in Nature (London) (16-11-2017)“…Phosphorylation-type (P-type) ATPases are ubiquitous primary transporters that pump cations across cell membranes through the formation and breakdown of a…”
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15
Crystal structure of the sodium-potassium pump
Published in Nature (13-12-2007)“…The Na+,K+-ATPase generates electrochemical gradients for sodium and potassium that are vital to animal cells, exchanging three sodium ions for two potassium…”
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16
A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b
Published in The Journal of biological chemistry (16-03-2018)“…The sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 2b isoform possesses an extended C terminus (SERCA2b tail) forming an 11th transmembrane (TM) helix, which…”
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Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2
Published in Proceedings of the National Academy of Sciences - PNAS (08-04-2014)“…P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet,…”
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18
Weak evidence of country- and institution-related status bias in the peer review of abstracts
Published in eLife (18-03-2021)“…Research suggests that scientists based at prestigious institutions receive more credit for their work than scientists based at less prestigious institutions,…”
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Distinct effects of Q925 mutation on intracellular and extracellular Na+ and K+ binding to the Na+, K+-ATPase
Published in Scientific reports (16-09-2019)“…Three Na + sites are defined in the Na + -bound crystal structure of Na + , K + -ATPase. Sites I and II overlap with two K + sites in the K + -bound structure,…”
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Asparagine 905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate–induced activation of ATP8A2 dephosphorylation
Published in The Journal of biological chemistry (12-04-2019)“…The P-type ATPase protein family includes, in addition to ion pumps such as Ca2+-ATPase and Na+,K+-ATPase, also phospholipid flippases that transfer…”
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