Search Results - "Anderle, Nicole"

Breast cancer patient-derived microtumors resemble tumor heterogeneity and enable protein-based stratification and functional validation of individualized drug treatment by Anderle, Nicole, Schäfer-Ruoff, Felix, Staebler, Annette, Kersten, Nicolas, Koch, André, ünder, Cansu, Keller, Anna-Lena, Liebscher, Simone, Hartkopf, Andreas, Hahn, Markus, Templin, Markus, Brucker, Sara Y, Schenke-Layland, Katja, Schmees, Christian

“…Abstract Despite tremendous progress in deciphering breast cancer at the genomic level, the pronounced intra- and intertumoral heterogeneity remains a major…”
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Generation and characterization of the human induced pluripotent stem cell line NMIi010-A from peripheral blood mononuclear cells of a healthy 49–year old male individual by Keller, Anna-Lena, Binner, Anna, Breitmeyer, Ricarda, Vogel, Sabrina, Anderle, Nicole, Rothbauer, Ulrich, Schenke-Layland, Katja, Schmees, Christian

“…Peripheral-blood derived CD34+ hematopoietic stem and progenitor cells were isolated from a 49-year old male donor and were successfully reprogrammed into…”
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Abstract PS17-42: A fast and effective 3D preclinical assay system comprised of patient derived breast cancer microtumors combined with DigiWest protein signaling pathway analyses for therapeutic response prediction (Project PRIMO) by Anderle, Nicole, Ruoff, Felix, Yuez, Simge, Koch, André, Hartkopf, Andreas, Brucker, Sara, Pawlak, Michael, Templin, Markus, Schmees, Christian

“…Abstract In the era of personalized medicine, the ability of pre-selecting individualized therapeutic options and pre-defining their suitability in advance of…”
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Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects by Dairkee, Shanaz H., Moore, Dan H., Luciani, M. Gloria, Anderle, Nicole, Gerona, Roy, Ky, Karina, Torres, Samantha M., Marshall, Polly V., Goodson III, William H.

“…Estrogenic overstimulation is carcinogenic to the human breast. Personal care products (PCPs) commonly contain xenoestrogens (XE), such as parabens and…”
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Targeting CSF1R Alone or in Combination with PD1 in Experimental Glioma by Przystal, Justyna M., Becker, Hannes, Canjuga, Denis, Tsiami, Foteini, Anderle, Nicole, Keller, Anna-Lena, Pohl, Anja, Ries, Carola H., Schmittnaegel, Martina, Korinetska, Nataliya, Koch, Marilin, Schittenhelm, Jens, Tatagiba, Marcos, Schmees, Christian, Beck, Susanne C., Tabatabai, Ghazaleh

“…Glioblastoma is an aggressive primary tumor of the central nervous system. Targeting the immunosuppressive glioblastoma-associated microenvironment is an…”
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TAMI-34. TARGETING CSF1R AND PD1 IN EXPERIMENTAL GLIOMA by Becker, Hannes, Przystal, Justyna M, Canjuga, Denis, Tsiami, Foteini, Anderle, Nicole, Keller, Anna-Lena, Pohl, Anja, Ries, Carola H, Schmittnaegel, Martina, Korinetska, Nataliya, Koch, Marilin, Schittenhelm, Jens, Tatagiba, Marcos, Schmees, Christian, Beck, Susanne C, Tabatabai, Ghazaleh

“…Abstract The treatment of glioblastoma remains a challenge. Novel therapeutic strategies are urgently needed. Targeting the immunosuppressive…”
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EXTH-48. NOVEL COMBINATION THERAPY IN PRECLINICAL GLIOMA MODELS USING THE CELL CYCLE STABILIZING COMPOUND ARGYRIN F AND CHECKPOINT INHIBITION by Walter, Bianca, Canjuga, Denis, Yuez, Simge G, Ghosh, Michael, Bozko, Przemyslaw, Przystal, Justyna, Govindarajan, Parameswari, Anderle, Nicole, Keller, Anna-Lena, Tatagiba, Marcos, Schenke-Layland, Katja, Rammensee, Hans-Georg, Stevanovic, Stefan, Malek, Nisar P, Schmees, Christian, Tabatabai, Ghazaleh

“…Abstract Glioblastoma are incurable aggressive tumors and remain a therapeutic challenge. Glioblastoma frequently harbor alterations in the retinoblastoma…”
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A Platform of Patient-Derived Microtumors Identifies Individual Treatment Responses and Therapeutic Vulnerabilities in Ovarian Cancer by Anderle, Nicole, Koch, André, Gierke, Berthold, Keller, Anna-Lena, Staebler, Annette, Hartkopf, Andreas, Brucker, Sara Y, Pawlak, Michael, Schenke-Layland, Katja, Schmees, Christian

“…In light of the frequent development of therapeutic resistance in cancer treatment, there is a strong need for personalized model systems representing patient…”
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Protein Profiling of Breast Carcinomas Reveals Expression of Immune-Suppressive Factors and Signatures Relevant for Patient Outcome by Ruoff, Felix, Kersten, Nicolas, Anderle, Nicole, Jerbi, Sandra, Stahl, Aaron, Koch, André, Staebler, Annette, Hartkopf, Andreas, Brucker, Sara Y, Hahn, Markus, Schenke-Layland, Katja, Schmees, Christian, Templin, Markus F

“…In cancer, the complex interplay between tumor cells and the tumor microenvironment results in the modulation of signaling processes. By assessing the…”
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Argyrin F Treatment‐Induced Vulnerabilities Lead to a Novel Combination Therapy in Experimental Glioma by Walter, Bianca, Canjuga, Denis, Yüz, Simge G., Ghosh, Michael, Bozko, Przemyslaw, Przystal, Justyna M., Govindarajan, Parameswari, Anderle, Nicole, Keller, Anna‐Lena, Tatagiba, Marcos, Schenke‐Layland, Katja, Rammensee, Hans‐Georg, Stevanovic, Stefan, Malek, Nisar P., Schmees, Christian, Tabatabai, Ghazaleh

“…Glioblastoma are incurable primary tumors of the central nervous system that frequently harbor molecular alterations in the retinoblastoma pathway with…”
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Patientenabgeleitete Mikrotumoren by Erne, Eva, Anderle, Nicole, Schmees, Christian, Stenzl, Arnulf

“…ZusammenfassungHintergrundDie personalisierte Tumortherapie rückt immer mehr in den Fokus onkologischer Behandlungsstrategien. Schnelle und effektive…”
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