Search Results - "Ancel, Caroline"
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Leptin, but not Estradiol, Signaling in PACAP Neurons Modulates Puberty Onset
Published in Endocrinology (Philadelphia) (01-08-2023)“…Abstract The adipose-derived hormone leptin critically modulates reproductive function, such that its absence results in hypothalamic hypogonadism. Pituitary…”
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2
RFamide-Related Peptide Neurons Modulate Reproductive Function and Stress Responses
Published in The Journal of neuroscience (20-01-2021)“…RF-amide related peptide 3 (RFRP-3) is a neuropeptide thought to inhibit central regulation of fertility. We investigated whether alterations in RFRP neuronal…”
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Central RFRP-3 Stimulates LH Secretion in Male Mice and Has Cycle Stage–Dependent Inhibitory Effects in Females
Published in Endocrinology (Philadelphia) (01-09-2017)“…RFamide-related peptide (RFRP)-3 is a neuropeptide thought to play an inhibitory role in the regulation of reproduction in various mammalian species, although…”
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Deletion of PTP1B From Brain Neurons Partly Protects Mice From Diet-Induced Obesity and Minimally Improves Fertility
Published in Endocrinology (Philadelphia) (01-02-2022)“…Reproductive dysfunction in women has been linked to high caloric diet (HCD)-feeding and obesity. Central resistance to leptin and insulin have been shown to…”
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Roles of RFRP-3 in the daily and seasonal regulation of reproductive activity in female Syrian hamsters
Published in Endocrinology (Philadelphia) (01-03-2017)“…In females, reproductive activity relies on proper integration of daily and environmental changes as well as cyclic sex-steroid feedback. This study aimed at…”
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Stimulatory Effect of RFRP-3 on the Gonadotrophic Axis in the Male Syrian Hamster: The Exception Proves the Rule
Published in Endocrinology (Philadelphia) (01-03-2012)“…In seasonal mammals, a distinct photoneuroendocrine circuit that involves the pineal hormone melatonin tightly synchronizes reproduction with seasons. In the…”
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RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents
Published in Neuropharmacology (15-05-2017)“…Although opiates represent the most effective analgesics, their use in chronic treatments is associated with numerous side effects including the development of…”
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Agouti‐related peptide neuronal silencing overcomes delayed puberty in neonatally underfed male mice
Published in Journal of neuroendocrinology (01-10-2022)“…Agouti‐related peptide (AgRP) neurons are thought to indirectly regulate the activity of hypothalamic gonadotrophin‐releasing hormone neurons which control…”
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Kisspeptins and RFRP-3 Act in Concert to Synchronize Rodent Reproduction with Seasons
Published in Frontiers in neuroscience (01-01-2013)“…Seasonal mammals use the photoperiodic variation in the nocturnal production of the pineal hormone melatonin to synchronize their reproductive activity with…”
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SAT-423 The Involvement of GnRH Neurons in Mediating the Effects of RFRP-3 on the Mouse Reproductive Axis
Published in Journal of the Endocrine Society (30-04-2019)“…In 2000, gonadotrophin-inhibitory hormone was discovered in birds and shown to inhibit gonadotrophin secretion. The mammalian ortholog was concurrently…”
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Development of Dipeptidic h GPR54 Agonists
Published in ChemMedChem (06-10-2016)“…Abstract A series of dipeptides were designed as potential agonists of the human KiSS1‐derived peptide receptor ( h GPR54). While the sequence Arg‐Trp‐NH 2 was…”
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Development of Dipeptidic hGPR54 Agonists
Published in ChemMedChem (06-10-2016)“…A series of dipeptides were designed as potential agonists of the human KiSS1‐derived peptide receptor (hGPR54). While the sequence Arg‐Trp‐NH2 was the most…”
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RFRP neurons are critical gatekeepers for the photoperiodic control of reproduction
Published in Frontiers in endocrinology (Lausanne) (2012)“…Seasonally breeding mammals rely on the photoperiodic signal to restrict their fertility to a certain time of the year. The photoperiodic information is…”
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14
A kiss for daily and seasonal reproduction
Published in Progress in brain research (2012)“…Reproduction is a fundamental biological function ensuring individual descendant survival and species perpetuity. It is an energy-consuming process, and…”
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