Search Results - "Anaya, Jordan"

OncoLnc: linking TCGA survival data to mRNAs, miRNAs, and lncRNAs by Anaya, Jordan

“…OncoLnc is a tool for interactively exploring survival correlations, and for downloading clinical data coupled to expression data for mRNAs, miRNAs, or long…”
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The lncRNA DRAIC/PCAT29 Locus Constitutes a Tumor-Suppressive Nexus by Sakurai, Kouhei, Reon, Brian J, Anaya, Jordan, Dutta, Anindya

“…Long noncoding RNAs (lncRNA) are emerging as major regulators of cellular phenotypes and implicated as oncogenes or tumor suppressors. Here, we report a novel…”
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The Role of Tryptophan Metabolites in Musculoskeletal Stem Cell Aging by Anaya, Jordan Marcano, Bollag, Wendy B, Hamrick, Mark W, Isales, Carlos M

“…Although aging is considered a normal process, there are cellular and molecular changes that occur with aging that may be detrimental to health. Osteoporosis…”
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Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis by Reon, Brian J, Anaya, Jordan, Zhang, Ying, Mandell, James, Purow, Benjamin, Abounader, Roger, Dutta, Anindya

“…Each year, over 16,000 patients die from malignant brain cancer in the US. Long noncoding RNAs (lncRNAs) have recently been shown to play critical roles in…”
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A pan-cancer analysis of prognostic genes by Anaya, Jordan, Reon, Brian, Chen, Wei-Min, Bekiranov, Stefan, Dutta, Anindya

“…Numerous studies have identified prognostic genes in individual cancers, but a thorough pan-cancer analysis has not been performed. In addition, previous…”
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Statistical heartburn: an attempt to digest four pizza publications from the Cornell Food and Brand Lab by van der Zee, Tim, Anaya, Jordan, Brown, Nicholas J L

“…We present the results of a reanalysis of four articles from the Cornell Food and Brand Lab based on data collected from diners at an Italian restaurant…”
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Unusual Vascular Distribution in the Third Segment of the Axillary Artery by Ramos-Alicea, Daniel, Marcano-Anaya, Jordan, Loomis, Mario, Ramirez, Norman, Quiñones-Rodríguez, Jailenne I

“…The third segment of the axillary artery (TSAA) is the main vascular supply to the muscles of the upper limb. Numerous studies have reported atypical branching…”
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tRFdb: a database for transfer RNA fragments by Kumar, Pankaj, Mudunuri, Suresh B., Anaya, Jordan, Dutta, Anindya

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Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets by Kumar, Pankaj, Anaya, Jordan, Mudunuri, Suresh B, Dutta, Anindya

“…tRFs, 14 to 32 nt long single-stranded RNA derived from mature or precursor tRNAs, are a recently discovered class of small RNA that have been found to be…”
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tRFdb: a database for transfer RNA fragments by Kumar, Pankaj, Mudunuri, Suresh B, Anaya, Jordan, Dutta, Anindya

“…We have created tRFdb, the first database of transfer RNA fragments (tRFs), available at http://genome.bioch.virginia.edu/trfdb/. With over 100 small RNA…”
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Abstract 1093: Calibration Tool for Genomic Aggregates (CTGA): A deep learning framework for calibrating somatic mutation profiling data from conventional gene panel data by Anaya, Jordan, Cummings, Craig, Lee, Jocelyn, Baras, Alexander

“…Abstract It has been suggested that aggregate genomic measures such as mutational burden can be associated with response to immunotherapy. Arguably, the gold…”
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1272 Probabilistic mixture models improve calibration of panel-derived tumor mutational burden in the context of both tumor-normal and tumor-only sequencing by Anaya, Jordan, John-William Sidhom, Baras, Alexander

“…BackgroundTumor mutational burden (TMB) has been investigated as a biomarker for immune checkpoint blockade (ICB) therapy. Increasingly, TMB is being estimated…”
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Characterization of non-monotonic relationships between tumor mutational burden and clinical outcomes by Anaya, Jordan, Kung, Julia, Baras, Alexander S

“…Potential clinical biomarkers are often assessed with Cox regressions or their ability to differentiate two groups of patients based on a single cutoff…”
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Surgical Implications in Multiple Variants in the Axillary Artery by Ramos Alicea, Daniel A., Marcano Anaya, Jordan, Pagan, John M., Ramirez, Norman, I. Quiñones Rodriguez, Jailenne

“…The third segment of the axillary artery (TSAA) contributes crucial irrigation to muscles in mostly all compartments of the upper limb. Numerous studies have…”
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Transfer RNA Fragments (tRFs) , Novel MicroRNA‐like Short RNAs Generated independent of Dicer, Associate with Target mRNAs in Ago complexes and are De‐regulated in Many Cancers by Dutta, Anindya, Anaya, Jordan, Kumar, Pankaj

“…Abstract only…”
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Kynurenine induces an age-related phenotype in bone marrow stromal cells by Patel, Dhara, Potter, Matthew, Anaya, Jordan Marcano, McGee-Lawrence, Meghan E., Hamrick, Mark W., Hill, William D., Isales, Carlos M., Fulzele, Sadanand

“…[Display omitted] •Kynurenines induce reactive oxygen species in BMSCs.•Kynurenine suppresses osteoblastic cellular energetics in BMSCs.•Kynurenine inhibits…”
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Multiple-instance learning of somatic mutations for the classification of tumour type and the prediction of microsatellite status by Anaya, Jordan, Sidhom, John-William, Mahmood, Faisal, Baras, Alexander S.

“…Large-scale genomic data are well suited to analysis by deep learning algorithms. However, for many genomic datasets, labels are at the level of the sample…”
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Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers by Scharpf, Robert B, Balan, Archana, Ricciuti, Biagio, Fiksel, Jacob, Cherry, Christopher, Wang, Chenguang, Lenoue-Newton, Michele L, Rizvi, Hira A, White, James R, Baras, Alexander S, Anaya, Jordan, Landon, Blair V, Majcherska-Agrawal, Marta, Ghanem, Paola, Lee, Jocelyn, Raskin, Leon, Park, Andrew S, Tu, Huakang, Hsu, Hil, Arbour, Kathryn C, Awad, Mark M, Riely, Gregory J, Lovly, Christine M, Anagnostou, Valsamo

“…The RAS family of small GTPases represents the most commonly activated oncogenes in human cancers. To better understand the prevalence of somatic RAS mutations…”
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Probabilistic Mixture Models Improve Calibration of Panel-derived Tumor Mutational Burden in the Context of both Tumor-normal and Tumor-only Sequencing by Anaya, Jordan, Sidhom, John-William, Cummings, Craig A, Baras, Alexander S

“…Tumor mutational burden (TMB) has been investigated as a biomarker for immune checkpoint blockade (ICB) therapy. Increasingly, TMB is being estimated with gene…”
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A structural role for the PHP domain in E. coli DNA polymerase III by Barros, Tiago, Guenther, Joel, Kelch, Brian, Anaya, Jordan, Prabhakar, Arjun, O'Donnell, Mike, Kuriyan, John, Lamers, Meindert H

“…In addition to the core catalytic machinery, bacterial replicative DNA polymerases contain a Polymerase and Histidinol Phosphatase (PHP) domain whose function…”
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