Search Results - "Anavi, Sarit"

Mechanism for HIF-1 activation by cholesterol under normoxia: A redox signaling pathway for liver damage by Anavi, Sarit, Hahn-Obercyger, Michal, Madar, Zecharia, Tirosh, Oren

“…Cholesterol and chronic activation of hypoxia-inducible factor-1 (HIF-1) have been separately implicated in the pathogenesis and progression of liver diseases…”
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Non-alcoholic fatty liver disease, to struggle with the strangle: Oxygen availability in fatty livers by Anavi, Sarit, Madar, Zecharia, Tirosh, Oren

“…Nonalcoholic fatty liver diseases (NAFLD) is one of the most common chronic liver disease in Western countries. Oxygen is a central component of the cellular…”
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Steatosis-induced proteins adducts with lipid peroxidation products and nuclear electrophilic stress in hepatocytes by Anavi, Sarit, Ni, Zhixu, Tirosh, Oren, Fedorova, Maria

“…Accumulating evidence suggests that fatty livers are particularly more susceptible to several pathological conditions, including hepatic inflammation,…”
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A novel antihypoglycemic role of inducible nitric oxide synthase in liver inflammatory response induced by dietary cholesterol and endotoxemia by Anavi, Sarit, Hahn-Obercyger, Michal, Margalit, Raanan, Madar, Zecharia, Tirosh, Oren

“…The current study aim was to elucidate the antihypoglycemic role and mechanism of inducible nitric oxide synthase (iNOS) under inflammatory stress. Liver…”
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iNOS as a metabolic enzyme under stress conditions by Anavi, Sarit, Tirosh, Oren

“…Nitric oxide (NO) is a free radical acting as a cellular signaling molecule in many different biochemical processes. NO is synthesized from l-arginine through…”
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The neuroprotective properties of a novel variety of passion fruit by Tal, Yael, Anavi, Sarit, Reisman, Merav, Samach, Alon, Tirosh, Oren, Troen, Aron M.

“…•The neuroprotective potential of a new line of passion fruit was tested in vitro and in vivo.•An extract of the new fruit prevented cultured neurons from…”
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Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes by Budick-Harmelin, Noga, Anavi, Sarit, Madar, Zecharia, Tirosh, Oren

“…Hepatic gluconeogenesis tightly controls blood glucose levels in healthy individuals, yet disorders of fatty acids (FAs) oxidation are characterized by…”
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Chiliadenus iphionoides Reduces Body Weight and Improves Parameters Related to Hepatic Lipid and Glucose Metabolism in a High-Fat-Diet-Induced Mice Model of NAFLD by Zandani, Gil, Anavi-Cohen, Sarit, Yudelevich, Tamar, Nyska, Abraham, Dudai, Nativ, Madar, Zecharia, Gorelick, Jonathan

“…Non-alcoholic fatty liver disease (NAFLD) has become an epidemic with increasing prevalence. Limited treatment options and poor adherence emphasize the urgent…”
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Broccoli Florets Supplementation Improves Insulin Sensitivity and Alters Gut Microbiome Population—A Steatosis Mice Model Induced by High-Fat Diet by Zandani, Gil, Anavi-Cohen, Sarit, Tsybina-Shimshilashvili, Nina, Sela, Noa, Nyska, Abraham, Madar, Zecharia

“…Nonalcoholic fatty liver disease (NAFLD) is linked to obesity, type 2 diabetes, hyperlipidemia, and gut dysbiosis. Gut microbiota profoundly affects the host…”
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Effects of high oleic acid peanuts on mice's liver and adipose tissue metabolic parameters and gut microbiota composition by Anavi-Cohen, Sarit, Tsybina-Shimshilashvili, Nina, Zandani, Gil, Hovav, Ran, Sela, Noa, Nyska, Abraham, Madar, Zecharia

“…This study aimed to investigate the effects of two types of peanuts, regular Hanoch (HN) and a new high-oleic cultivar., Hanoch-Oleic (HO), on metabolic…”
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Nutritional lipid-induced oxidative stress leads to mitochondrial dysfunction followed by necrotic death in FaO hepatocytes by Tirosh, Oren, Ph.D, Ilan, Erez, Ph.D, Anavi, Sarit, M.Sc, Ramadori, Giuliano, M.D, Madar, Zecharia, Ph.D

“…Abstract Objective Mitochondrial dysfunction and hepatocyte cell death have been reported in fatty liver and non-alcoholic steatohepatitis. Our aim in this…”
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Metabolic and Microbiome Alterations Following the Enrichment of a High-Fat Diet With High Oleic Acid Peanuts Versus the Traditional Peanuts Cultivar in Mice by Anavi-Cohen, Sarit, Zandani, Gil, Tsybina-Shimshilashvili, Nina, Hovav, Ran, Sela, Noa, Nyska, Abraham, Madar, Zecharia

“…A new Israeli-developed peanut cultivar, “Hanoch-Oleic” (HO), uniquely contains enlarged oleic acid contents and was designed to confer additional beneficial…”
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The role of iNOS in cholesterol-induced liver fibrosis by Anavi, Sarit, Eisenberg-Bord, Michal, Hahn-Obercyger, Michal, Genin, Olga, Pines, Mark, Tirosh, Oren

“…Accumulation of cholesterol in the liver is associated with the development of non-alcoholic steatohepatitis-related fibrosis. However, underlying mechanisms…”
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Prolonged feeding with green tea polyphenols exacerbates cholesterol-induced fatty liver disease in mice by Hirsch, Nina, Konstantinov, Anya, Anavi, Sarit, Aronis, Anna, Hagay, Zion, Madar, Zecharia, Tirosh, Oren

“…Scope This study investigated the potential deleterious impact of dietary supplementation with green tea extract (GTE) on the progression of fatty liver…”
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Beneficial role of nitric oxide in cholesterol-induced steatohepatitis and LPS-induced endotoxemia by Anavi, Sarit, Madar, Zecharia, Tirosh, Oren

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Oxidative stress impairs HIF1α activation: a novel mechanism for increased vulnerability of steatotic hepatocytes to hypoxic stress by Anavi, Sarit, Harmelin, Noga Budick, Madar, Zecharia, Tirosh, Oren

“…Steatosis increases the sensitivity of hepatocytes to hypoxic injury. Thus, this study was designed to elucidate the role of hypoxia-inducible factor-1α…”
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Tea Extracts-induced Liver Injury: Lipotoxic Interaction Between Lipids and Polyphenols by Tirosh, Oren, Hirsch, Nina, Konstantinov, Anya, Anavi, Sarit, Aronis, Anna, Hagay, Zion, Madar, Zecharia

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OP-17 - Tea Extracts-induced Liver Injury: Lipotoxic Interaction Between Lipids and Polyphenols by Tirosh, Oren, Hirsch, Nina, Konstantinov, Anya, Anavi, Sarit, Aronis, Anna, Hagay, Zion, Madar, Zecharia

“…Green tea polyphenol extracts (GTE) are sold commercially as cholesterol-reducing agents and for weight reduction however, they have also been reported to be…”
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Activation of HIF‐1 pathway by cholesterol in hepatocytes under normoxia (649.1) by Anavi, Sarit, Hahn Obercyger, Michal, Madar, Zecharia, Tirosh, Oren

“…Hypoxia inducible factor‐1 (HIF‐1) and cholesterol have been separately implicated in the development of several liver pathologies. The aim of the present…”
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L-arginine conjugates of bile acids-a possible treatment for non-alcoholic fatty liver disease by Voloshin, Irina, Hahn-Obercyger, Michal, Anavi, Sarit, Tirosh, Oren

“…Non-alcoholic fatty liver disease (NAFLD) is a continuum of diseases that include simple steatosis and non-alcoholic steatohepatitis (NASH) ultimately leading…”
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