Search Results - "Anat, A"

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  1. 1

    Prophage Excision Activates Listeria Competence Genes that Promote Phagosomal Escape and Virulence by Rabinovich, Lev, Sigal, Nadejda, Borovok, Ilya, Nir-Paz, Ran, Herskovits, Anat A.

    Published in Cell (17-08-2012)
    “…The DNA uptake competence (Com) system of the intracellular bacterial pathogen Listeria monocytogenes is considered nonfunctional. There are no known…”
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  2. 2

    A new perspective on lysogeny: prophages as active regulatory switches of bacteria by Feiner, Ron, Argov, Tal, Rabinovich, Lev, Sigal, Nadejda, Borovok, Ilya, Herskovits, Anat A.

    Published in Nature reviews. Microbiology (01-10-2015)
    “…In this Opinion article, Herskovits and colleagues introduce an emerging class of bacteria–phage symbiotic interaction — which they term 'active lysogeny' — in…”
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  3. 3

    Systems Level Analyses Reveal Multiple Regulatory Activities of CodY Controlling Metabolism, Motility and Virulence in Listeria monocytogenes by Lobel, Lior, Herskovits, Anat A

    Published in PLoS genetics (19-02-2016)
    “…Bacteria sense and respond to many environmental cues, rewiring their regulatory network to facilitate adaptation to new conditions/niches. Global…”
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  4. 4

    Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulence by Lobel, Lior, Sigal, Nadejda, Borovok, Ilya, Ruppin, Eytan, Herskovits, Anat A

    Published in PLoS genetics (01-09-2012)
    “…Intracellular bacterial pathogens are metabolically adapted to grow within mammalian cells. While these adaptations are fundamental to the ability to cause…”
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  5. 5

    Temperate bacteriophages as regulators of host behavior by Argov, Tal, Azulay, Gil, Pasechnek, Anna, Stadnyuk, Olga, Ran-Sapir, Shai, Borovok, Ilya, Sigal, Nadejda, Herskovits, Anat A

    Published in Current opinion in microbiology (01-08-2017)
    “…Highlights • Lysogeny provides a unique state that promotes bacterial–phage mutualistic interactions. • Temperate phages regulate bacterial gene expression and…”
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  6. 6

    Active Lysogeny in Listeria Monocytogenes Is a Bacteria-Phage Adaptive Response in the Mammalian Environment by Pasechnek, Anna, Rabinovich, Lev, Stadnyuk, Olga, Azulay, Gil, Mioduser, Jessica, Argov, Tal, Borovok, Ilya, Sigal, Nadejda, Herskovits, Anat A.

    Published in Cell reports (Cambridge) (28-07-2020)
    “…Some Listeria monocytogenes (Lm) strains harbor a prophage within the comK gene, which renders it inactive. During Lm infection of macrophage cells, the…”
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  7. 7

    Controlled branched-chain amino acids auxotrophy in Listeria monocytogenes allows isoleucine to serve as a host signal and virulence effector by Brenner, Moran, Lobel, Lior, Borovok, Ilya, Sigal, Nadejda, Herskovits, Anat A

    Published in PLoS genetics (12-03-2018)
    “…Listeria monocytogenes (Lm) is a saprophyte and intracellular pathogen. Transition to the pathogenic state relies on sensing of host-derived metabolites, yet…”
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  8. 8

    An Effective Counterselection System for Listeria monocytogenes and Its Use To Characterize the Monocin Genomic Region of Strain 10403S by Argov, Tal, Rabinovich, Lev, Sigal, Nadejda, Herskovits, Anat A

    Published in Applied and environmental microbiology (15-03-2017)
    “…Construction of mutants by allelic exchange has been laborious and time-consuming due to lack of proficient selection markers for the final recombination…”
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  9. 9

    Coordination of cohabiting phage elements supports bacteria–phage cooperation by Argov, Tal, Sapir, Shai Ran, Pasechnek, Anna, Azulay, Gil, Stadnyuk, Olga, Rabinovich, Lev, Sigal, Nadejda, Borovok, Ilya, Herskovits, Anat A.

    Published in Nature communications (21-11-2019)
    “…Bacterial pathogens often carry multiple prophages and other phage-derived elements within their genome, some of which can produce viral particles in response…”
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  10. 10

    Organizational commitment and quality of life at work among public health nurses in Israel by Aharon, Anat A., Madjar, Batya, Kagan, Ilya

    Published in Public health Nursing (01-07-2019)
    “…Objective To test the relationship between job satisfaction, professional self‐image, work environment, organizational commitment (OC), and quality of life at…”
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  11. 11

    Listeria monocytogenes TcyKLMN Cystine/Cysteine Transporter Facilitates Glutathione Synthesis and Virulence Gene Expression by Brenner, Moran, Friedman, Sivan, Haber, Adi, Livnat-Levanon, Nurit, Borovok, Ilya, Sigal, Nadejda, Lewinson, Oded, Herskovits, Anat A

    Published in mBio (28-06-2022)
    “…Listeria monocytogenes is a saprophyte and a human intracellular pathogen. Upon invasion into mammalian cells, it senses multiple metabolic and environmental…”
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  12. 12

    The metabolic regulator CodY links Listeria monocytogenes metabolism to virulence by directly activating the virulence regulatory gene prfA by Lobel, Lior, Sigal, Nadejda, Borovok, Ilya, Belitsky, Boris R., Sonenshein, Abraham L., Herskovits, Anat A.

    Published in Molecular microbiology (01-02-2015)
    “…Summary Metabolic adaptations are critical to the ability of bacterial pathogens to grow within host cells and are normally preceded by sensing of…”
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  13. 13

    L-glutamine Induces Expression of Listeria monocytogenes Virulence Genes by Haber, Adi, Friedman, Sivan, Lobel, Lior, Burg-Golani, Tamar, Sigal, Nadejda, Rose, Jessica, Livnat-Levanon, Nurit, Lewinson, Oded, Herskovits, Anat A

    Published in PLoS pathogens (01-01-2017)
    “…The high environmental adaptability of bacteria is contingent upon their ability to sense changes in their surroundings. Bacterial pathogen entry into host…”
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  14. 14

    A dual-function phage regulator controls the response of cohabiting phage elements via regulation of the bacterial SOS response by Azulay, Gil, Pasechnek, Anna, Stadnyuk, Olga, Ran-Sapir, Shai, Fleisacher, Ana Mejia, Borovok, Ilya, Sigal, Nadejda, Herskovits, Anat A.

    Published in Cell reports (Cambridge) (19-04-2022)
    “…Listeria monocytogenes strain 10403S harbors two phage elements in its chromosome; one produces infective virions and the other tailocins. It was previously…”
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  15. 15
  16. 16

    Bacterial ligands generated in a phagosome are targets of the cytosolic innate immune system by Herskovits, Anat A, Auerbuch, Victoria, Portnoy, Daniel A

    Published in PLoS pathogens (01-03-2007)
    “…Macrophages are permissive hosts to intracellular pathogens, but upon activation become microbiocidal effectors of innate and cell-mediated immunity. How the…”
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  17. 17

    Metabolic Genetic Screens Reveal Multidimensional Regulation of Virulence Gene Expression in Listeria monocytogenes and an Aminopeptidase That Is Critical for PrfA Protein Activation by Friedman, Sivan, Linsky, Marika, Lobel, Lior, Rabinovich, Lev, Sigal, Nadejda, Herskovits, Anat A

    Published in Infection and immunity (01-06-2017)
    “…is an environmental saprophyte and intracellular bacterial pathogen. Upon invading mammalian cells, the bacterium senses abrupt changes in its metabolic…”
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  18. 18

    Listeria monocytogenes Multidrug Resistance Transporters and Cyclic Di-AMP, Which Contribute to Type I Interferon Induction, Play a Role in Cell Wall Stress by Kaplan Zeevi, Millie, Shafir, Nirit S, Shaham, Shira, Friedman, Sivan, Sigal, Nadejda, Nir Paz, Ran, Boneca, Ivo G, Herskovits, Anat A

    Published in Journal of Bacteriology (01-12-2013)
    “…The intracellular bacterial pathogen Listeria monocytogenes activates a robust type I interferon response upon infection. This response is partially dependent…”
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  19. 19

    Metabolism of the Gram-Positive Bacterial Pathogen Listeria monocytogenes by Sauer, John-Demian, Herskovits, Anat A, O'Riordan, Mary X D

    Published in Microbiology spectrum (01-07-2019)
    “…Bacterial metabolism represents the biochemical space that bacteria can manipulate to produce energy, reducing equivalents and building blocks for replication…”
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  20. 20

    The human P-glycoprotein transporter enhances the type I interferon response to Listeria monocytogenes infection by Sigal, Nadejda, Kaplan Zeevi, Millie, Weinstein, Shiri, Peer, Dan, Herskovits, Anat A

    Published in Infection and immunity (01-06-2015)
    “…Human multidrug efflux transporters are known for their ability to extrude antibiotics and toxic compounds out of cells, yet accumulating data indicate they…”
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