Search Results - "Anastasiadi, Alkmini T."

E Pluribus, Unum: Emergent Redox Harmony from the Chaos of Blood Cells by Anastasiadi, Alkmini T, D'Alessandro, Angelo

“…Blood cells play a fundamental role in maintaining systemic homeostasis, by responding dynamically to various physiological and environmental stimuli [...]…”
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Beta thalassemia minor is a beneficial determinant of red blood cell storage lesion by Tzounakas, Vassilis L, Anastasiadi, Alkmini T, Stefanoni, Davide, Cendali, Francesca, Bertolone, Lorenzo, Gamboni, Fabia, Dzieciatkowska, Monika, Rousakis, Pantelis, Vergaki, Athina, Soulakis, Vassilis, Tsitsilonis, Ourania E, Stamoulis, Konstantinos, Papassideri, Issidora S, Kriebardis, Anastasios G, D'Alessandro, Angelo, Antonelou, Marianna H

“…Blood donor genetics and lifestyle affect the quality of red blood cell (RBC) storage. Heterozygotes for beta thalassemia (bThal+) constitute a non-negligible…”
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Molecular modifications to mitigate oxidative stress and improve red blood cell storability by Anastasiadi, Alkmini T., Stamoulis, Konstantinos, Kriebardis, Anastasios G., Tzounakas, Vassilis L.

“…The development of red blood cell (RBC) storage lesion during hypothermic storage has long posed challenges for blood transfusion efficacy. These alterations…”
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A Current Synopsis of the Emerging Role of Extracellular Vesicles and Micro-RNAs in Pancreatic Cancer: A Forward-Looking Plan for Diagnosis and Treatment by Trifylli, Eleni Myrto, Kriebardis, Anastasios G, Koustas, Evangelos, Papadopoulos, Nikolaos, Fortis, Sotirios P, Tzounakas, Vassilis L, Anastasiadi, Alkmini T, Sarantis, Panagiotis, Vasileiadi, Sofia, Tsagarakis, Ariadne, Aloizos, Georgios, Manolakopoulos, Spilios, Deutsch, Melanie

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies worldwide, while it persists as the fourth most prevalent cause of cancer-related…”
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Proteome of Stored RBC Membrane and Vesicles from Heterozygous Beta Thalassemia Donors by Tzounakas, Vassilis L, Anastasiadi, Alkmini T, Dzieciatkowska, Monika, Karadimas, Dimitrios G, Stamoulis, Konstantinos, Papassideri, Issidora S, Hansen, Kirk C, D'Alessandro, Angelo, Kriebardis, Anastasios G, Antonelou, Marianna H

“…Genetic characteristics of blood donors may impact the storability of blood products. Despite higher basal stress, red blood cells (RBCs) from eligible donors…”
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The Arising Role of Extracellular Vesicles in Cholangiocarcinoma: A Rundown of the Current Knowledge Regarding Diagnostic and Therapeutic Approaches by Trifylli, Eleni-Myrto, Kriebardis, Anastasios G., Koustas, Evangelos, Papadopoulos, Nikolaos, Vasileiadi, Sofia, Fortis, Sotirios P., Tzounakas, Vassilis L., Anastasiadi, Alkmini T., Sarantis, Panagiotis, Papageorgiou, Effie G., Tsagarakis, Ariadne, Aloizos, Georgios, Manolakopoulos, Spilios, Deutsch, Melanie

“…Cholangiocarcinomas (CCAs) constitute a heterogeneous group of highly malignant epithelial tumors arising from the biliary tree. This cluster of malignant…”
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Red Blood Cell Metabolism In Vivo and In Vitro by D'Alessandro, Angelo, Anastasiadi, Alkmini T, Tzounakas, Vassilis L, Nemkov, Travis, Reisz, Julie A, Kriebardis, Anastsios G, Zimring, James C, Spitalnik, Steven L, Busch, Michael P

“…Red blood cells (RBC) are the most abundant cell in the human body, with a central role in oxygen transport and its delivery to tissues. However, omics…”
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Deciphering the Relationship Between Free and Vesicular Hemoglobin in Stored Red Blood Cell Units by Tzounakas, Vassilis L, Anastasiadi, Alkmini T, Lekka, Marilena E, Papageorgiou, Effie G, Stamoulis, Konstantinos, Papassideri, Issidora S, Kriebardis, Anastasios G, Antonelou, Marianna H

“…Red blood cells (RBCs) release hemoglobin (Hb)-containing extracellular vesicles (EVs) throughout their lifespan in the circulation, and especially during…”
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The Post-Storage Performance of RBCs from Beta-Thalassemia Trait Donors Is Related to Their Storability Profile by Anastasiadi, Alkmini T, Paronis, Efthymios C, Arvaniti, Vasiliki-Zoi, Velentzas, Athanasios D, Apostolidou, Anastasia C, Balafas, Evangelos G, Dzieciatkowska, Monika, Kostomitsopoulos, Nikolaos G, Stamoulis, Konstantinos, Papassideri, Issidora S, D'Alessandro, Angelo, Kriebardis, Anastasios G, Antonelou, Marianna H, Tzounakas, Vassilis L

“…Blood donors with beta-thalassemia traits (βThal ) have proven to be good "storers", since their stored RBCs are resistant to lysis and resilient against…”
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Supplementation with uric and ascorbic acid protects stored red blood cells through enhancement of non-enzymatic antioxidant activity and metabolic rewiring by Tzounakas, Vassilis L., Anastasiadi, Alkmini T., Arvaniti, Vasiliki-Zoi, Lelli, Veronica, Fanelli, Giuseppina, Paronis, Efthymios C., Apostolidou, Anastasia C., Balafas, Evangelos G., Kostomitsopoulos, Nikolaos G., Papageorgiou, Effie G., Papassideri, Issidora S., Stamoulis, Konstantinos, Kriebardis, Anastasios G., Rinalducci, Sara, Antonelou, Marianna H.

“…Redox imbalance and oxidative stress have emerged as generative causes of the structural and functional degradation of red blood cells (RBC) that happens…”
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Innate Variability in Physiological and Omics Aspects of the Beta Thalassemia Trait-Specific Donor Variation Effects by Anastasiadi, Alkmini T, Tzounakas, Vassilis L, Dzieciatkowska, Monika, Arvaniti, Vasiliki-Zoi, Papageorgiou, Effie G, Papassideri, Issidora S, Stamoulis, Konstantinos, D'Alessandro, Angelo, Kriebardis, Anastasios G, Antonelou, Marianna H

“…The broad spectrum of beta-thalassemia ( Thal) mutations may result in mild reduction ( ), severe reduction ( ) or complete absence ( ) of beta-globin…”
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Early and Late-Phase 24 h Responses of Stored Red Blood Cells to Recipient-Mimicking Conditions by Tzounakas, Vassilis L., Anastasiadi, Alkmini T., Karadimas, Dimitrios G., Velentzas, Athanassios D., Anastasopoulou, Violetta I., Papageorgiou, Effie G., Stamoulis, Konstantinos, Papassideri, Issidora S., Kriebardis, Anastasios G., Antonelou, Marianna H.

“…The 24-hour (24 h) post-transfusion survival of donor red blood cells (RBCs) is an important marker of transfusion efficacy. Nonetheless, within that period,…”
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Red Blood Cell Proteasome in Beta-Thalassemia Trait: Topology of Activity and Networking in Blood Bank Conditions by Anastasiadi, Alkmini T., Tzounakas, Vassilis L., Arvaniti, Vasiliki-Zoi, Dzieciatkowska, Monika, Stamoulis, Konstantinos, Lekka, Marilena E., Papassideri, Issidora S., D’Alessandro, Angelo, Kriebardis, Anastasios G., Antonelou, Marianna H.

“…Proteasomes are multi-catalytic complexes with important roles in protein control. Their activity in stored red blood cells (RBCs) is affected by both storage…”
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The time-course linkage between hemolysis, redox, and metabolic parameters during red blood cell storage with or without uric acid and ascorbic acid supplementation by Anastasiadi, Alkmini T, Stamoulis, Konstantinos, Papageorgiou, Effie G, Lelli, Veronica, Rinalducci, Sara, Papassideri, Issidora S, Kriebardis, Anastasios G, Antonelou, Marianna H, Tzounakas, Vassilis L

“…Oxidative phenomena are considered to lie at the root of the accelerated senescence observed in red blood cells (RBCs) stored under standard blood bank…”
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Stratification of βSβ+ Compound Heterozygotes Based on L-Glutamine Administration and RDW: Focusing on Disease Severity by Giannaki, Aimilia, Georgatzakou, Hara Τ., Fortis, Sotirios P., Anastasiadi, Alkmini T., Pavlou, Efthimia G., Nomikou, Efrosyni G., Drandaki, Maria P., Kotsiafti, Angeliki, Xydaki, Aikaterini, Fountzoula, Christina, Papageorgiou, Effie G., Tzounakas, Vassilis L., Kriebardis, Anastasios G.

“…Sickle cell disease (SCD) is heterogeneous in terms of manifestation severity, even more so when in compound heterozygosity with beta-thalassemia. The aim of…”
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Corpuscular Fragility and Metabolic Aspects of Freshly Drawn Beta-Thalassemia Minor RBCs Impact Their Physiology and Performance Post Transfusion: A Triangular Correlation Analysis In Vitro and In Vivo by Anastasiadi, Alkmini T, Arvaniti, Vasiliki-Zoi, Paronis, Efthymios C, Kostomitsopoulos, Nikolaos G, Stamoulis, Konstantinos, Papassideri, Issidora S, D'Alessandro, Angelo, Kriebardis, Anastasios G, Tzounakas, Vassilis L, Antonelou, Marianna H

“…The clarification of donor variation effects upon red blood cell (RBC) storage lesion and transfusion efficacy may open new ways for donor-recipient matching…”
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Osmotic hemolysis is a donor‐specific feature of red blood cells under various storage conditions and genetic backgrounds by Tzounakas, Vassilis L., Anastasiadi, Alkmini T., Valsami, Serena I., Stamoulis, Konstantinos E., Papageorgiou, Effie G., Politou, Marianna, Papassideri, Issidora S., Kriebardis, Anastasios G., Antonelou, Marianna H.

“…Background Transfusion research has recently focused on the discovery of red blood cell (RBC) storage capacity biomarkers and the elucidation of donor…”
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Sex-related aspects of the red blood cell storage lesion by Tzounakas, Vassilis L., Anastasiadi, Alkmini T., Drossos, Panagiotis V., Karadimas, Dimitrios G., Valsami, Serena É., Stamoulis, Konstantinos E., Papassideri, Issidora S., Politou, Marianna, Antonelou, Marianna H., Kriebardis, Anastasios G.

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Leukoreduction makes a difference: A pair proteomics study of extracellular vesicles in red blood cell units by Tzounakas, Vassilis L., Stamoulis, Konstantinos E., Anastasiadi, Alkmini T., Papassideri, Issidora S., Kriebardis, Anastasios G., Rinalducci, Sara, Antonelou, Marianna H.

“…Prestorage filtration of blood to remove contaminating donor leukocytes and platelets has substantially increased the safety level of transfusion therapy. We…”
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Exploring unconventional attributes of red blood cells and their potential applications in biomedicine by Anastasiadi, Alkmini T, Arvaniti, Vasiliki-Zoi, Hudson, Krystalyn E, Kriebardis, Anastasios G, Stathopoulos, Constantinos, D'Alessandro, Angelo, Spitalnik, Steven L, Tzounakas, Vassilis L

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